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William T. Pu

Boston Children's Hospital

91H-index
333Paper Count
2.8WCitation Count
Published Papers 180
Publication Date
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SORBS2 regulates diastolic function through cytoskeletal networks and calcium handling
errCommunications Biology
IF5.1
err2026-06-17
err0
errOAAI
errZexuan Wu; Camille Blandin; Jiehui Chen; Jiajin Li; Li He; Qing Ma; Michael M. Peters; Anna Ponek; Dogacan Yucel; Kevin Kit Parker; Fujian Lu; William T. Pu
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An RYR2-interacting fragment of MYBPC3 mitigates arrhythmia in human iPSC-CM and mouse models of CPVT
errMolecular Therapy
IF12
err2026-05-05
err0
PREAI
errFujian Lu; Zexuan Wu; Shaopeng Chi; Jiajin Li; Anna Ponek; Carter Liou; Qing Ma; Durgesh Bonde; Nikoleta Pavlaki; Mason E. Sweat; Sanam Shafaattalab; Yashasvi Tharani; Maksymilian Prondzynski; Vassilios J. Bezzerides; William T. Pu
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errSave
PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy
errNature Cardiovascular Research
IF10.8
err2026-04-20
err0
errOAAI
errYao Wei Lu; Zhuomin Liang; Kerry Dorr; Samantha Ruiz; Xiaoran Huang; Denise Fangnibo Hanvi; Sheri M. Juntilla; Gisela Beutner; Shuhan Lyu; Haipeng Guo; Tiago Fernandes; Ramon A. Espinoza-Lewis; Tingting Wang; Kathryn Li; Xue Li; Gurinder Bir Singh; Yi Wang; Rui Deng; Douglas Cowan; John D. Mably; William T. Pu; Jessie Huang; George A. Porter; Frank Conlon; Hong Chen; Da-Zhi Wang
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errSave
Nrf1 coordinates proteasome activity and autophagy to maintain cardiac proteostasis
errCommunications Biology
IF5.1
err2026-04-17
err0
errOAAI
errLakindu P. Kankanamge; Hyunji An; Qin Guo; Maksymillian Prondzynski; Soon Ho Kwon; Durgesh Anil Bonde; William T. Pu; Eric N. Olson; Miao Cui
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errSave
Mechanotyping of Organoids for Assessing Drug-Induced Injuries
errAdvanced Materials
IF26.8
err2025-11-05
err0
PREAI
errMurat Kaynak; Mehmet D. Aşık; Elif E. Inan; Maksymilian Prondzynski; Hamzeh Ghasemzadeh; Amir Poorghani; Yashasvi Tharani; Matilda Holtz; Daryush D. Mehta; William T. Pu; Orhun K. Muratoglu; Martin L. Yarmush; Alexander Alexeev; O. Berk Usta
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The drug-elicitable alternative splicing module for tunable vector expression in the heart
errcardiovascular research
IF10.8
err2025-06-13
err0
PREAI
errZhan Chen; Luzi Yang; Yueyang Zhang; Jiting Li; Yuhan Yang; Yue Li; Linwei Fan; Wei Chen; Lei Miao; Jin Liu; Gonglie Chen; Ze Wang; Yifei Li; Fei Gao; Jing Zhou; Lemin Zheng; Yan Zhang; Dongyu Zhao; William T. Pu; Ke Yang; Erdan Dong; Yuxuan Guo
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errSave
Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages
errCell Stem Cell
IF20.4
err2025-06-13
err0
PREAI
errLiyan Gong; Yadong Zhang; Yonglin Zhu; Umji Lee; Allen Chilun Luo; Xiang Li; Xi Wang; Danyang Chen; William T. Pu; Ruei-Zeng Lin; Minglin Ma; Miao Cui; Kaifu Chen; Kai Wang; Juan M. Melero-Martin
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errSave
Pioneer factor ETV2 safeguards endothelial cell specification by recruiting the repressor REST to restrict alternative lineage commitment
errcardiovascular research
IF10.8
err2025-06-10
err0
PREAI
errDanyang Chen; Xiaonuo Fan; Ninghe Sun; Kai Wang; Liyan Gong; Juan M. Melero-Martin; William T. Pu
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errSave
SCIG: Machine learning uncovers cell identity genes in single cells by genetic sequence codes
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-05-28
err0
errOAAI
errArulsamy, Kulandaisamy; Xia, Bo; Yu, Yang; Chen, Hong; Pu, William T.; Zhang, Lili; Chen, Kaifu
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errSave
Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy
errNATURE COMMUNICATIONS
IF15.7
err2025-04-16
err0
errOAAI
errYoshinaga, Daisuke; Craven, Isabel; Feng, Rui; Prondzynski, Maksymilian; Shani, Kevin; Tharani, Yashasvi; Mayourian, Joshua; Joseph, Milosh; Walker, David; Bortolin, Raul H.; Carreon, Chrystalle Katte; Boss, Bridget; Upton, Sheila; Parker, Kevin Kit; Pu, William T.; Bezzerides, Vassilios J.
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errSave
Non-Cell-Autonomous Cardiomyocyte Regulation Complicates Gene Supplementation Therapy for Lmna-Associated Cardiac Defects in Mice
errJACC-BASIC TO TRANSLATIONAL SCIENCE
IF7.2
err2024-11-01
err0
errOAAI
errSun, Yueshen; Guo, Congting; Chen, Zhan; Lin, Junsen; Yang, Luzi; Zhang, Yueyang; Wu, Chenyang; Zhao, Dongyu; Jardin, Blake; Pu, William T.; Zhao, Mingming; Dong, Erdan; Hu, Xiaomin; Zhang, Shuyang; Guo, Yuxuan
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errSave
Antisense Oligonucleotide Therapy for Calmodulinopathy
errCIRCULATION
IF38.6
err2024-10-08
err0
PREAI
errBortolin, Raul H.; Nawar, Farina; Park, Chaehyoung; Trembley, Michael A.; Prondzynski, Maksymilian; Sweat, Mason E.; Wang, Peizhe; Chen, Jiehui; Lu, Fujian; Liou, Carter; Berkson, Paul; Keating, Erin M.; Yoshinaga, Daisuke; Pavlaki, Nikoleta; Samenuk, Thomas; Cavazzoni, Cecilia B.; Sage, Peter T.; Ma, Qing; Whitehill, Robert D.; Abrams, Dominic J.; Carreon, Chrystalle Katte; Putra, Juan; Alexandrescu, Sanda; Guo, Shuai; Tsai, Wen-Chin; Rubart, Michael; Kubli, Dieter A.; Mullick, Adam E.; Bezzerides, Vassilios J.; Pu, William T.
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Virally delivered CMYA5 enhances the assembly of cardiac dyads
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-09-05
err0
PREAI
errLu, Fujian; Liou, Carter; Ma, Qing; Wu, Zexuan; Xue, Bingqing; Xia, Yu; Xia, Shutao; Trembley, Michael A.; Ponek, Anna; Xie, Wenjun; Shani, Kevin; Bortolin, Raul H.; Prondzynski, Maksymilian; Berkson, Paul; Zhang, Xiaoran; Naya, Francisco J.; Bedi, Kenneth C.; Margulies, Kenneth B.; Zhang, Donghui; Parker, Kevin K.; Pu, William T.
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errSave
Activation of VGLL4 Suppresses Cardiomyocyte Maturational Hypertrophic Growth
errCELLS
IF5.2
err2024-08-13
err0
errOAAI
errFarley, Aaron; Gao, Yunan; Sun, Yan; Zohrabian, Sylvia; Pu, William T.; Lin, Zhiqiang
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errSave
RBFOX2 haploinsufficiency impairs cardiomyocyte adhesion and contractility through faulty RNA metabolism
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errHuang, Mengmeng; Gao, Xinlei; Trembley, Michael; Prondzynski, Maksymilian; Tharani, Yashasvi; Nawar, Farina; Zheng, Rongbin; Aigner, Stefan; Yeo, Gene; Pu, William; Chen, Kaifu; Burns, C. Geoffrey; Burns, Caroline
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errSave
Antisense Oligonucleotide Treatment of Calmodulinopathy
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errBortolin, Raul; Nawar, Farina; Trembley, Michael; Prondzynski, Maksymilian; Sweat, Mason; Wang, Peizhe; Chaehyoung, Park; Lu, Fujian; Keating, Erin; Yoshinaga, Daisuke; Pavlaki, Nikoleta; Cavazzoni, Cecilia B.; Sage, Peter T.; Whitehill, Robert D.; Abrams, Dominic; Carreon, Chrystalle; Putra, Juan; Alexandrescu, Sanda; Guo, Shuai; Tsai, Owen; Rubart, Michael; Kubli, Dieter; Mullick, Adam; Bezzerides, Vassilios; Pu, William
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errSave
CHD4 Interacts With TBX5 to Maintain the Gene Regulatory Network of Postnatal Atrial Cardiomyocytes
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errSweat, Mason; Shi, Wei; Keating, Erin; Ponek, Anna; Conlon, Frank; Pu, William
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errSave
In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-disc-associated mitigator of isoproterenol-induced cardiac injury
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-07-23
err0
PREAI
errGuo, Cong-ting; Jardin, Blake D.; Lin, Jun-sen; Ambroise, Rachelle L.; Wang, Ze; Yang, Lu-zi; Mazumdar, Neil; Lu, Fu-jian; Ma, Qing; Cao, Yang-po; Liu, Can-zhao; Li, Kai-long; Liu, Xu-jie; Lan, Feng; Zhao, Ming-ming; Xiao, Han; Dong, Er-dan; Pu, William T.; Guo, Yu-xuan
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errSave
Allele-Specific Suppression of Variant MHC With High-Precision RNA Nuclease CRISPR-Cas13d Prevents Hypertrophic Cardiomyopathy
errCIRCULATION
IF38.6
err2024-07-23
err2
errOAAI
errYang, Ping; Lou, Yingmei; Geng, Zilong; Guo, Zhizhao; Wu, Shuo; Li, Yige; Song, Kaiyuan; Shi, Ting; Zhang, Shasha; Xiong, Junhao; Chen, Alex F.; Li, Dali; Pu, William T.; Da, Lintai; Zhang, Yan; Sun, Kun; Zhang, Bing
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errSave
Therapeutic Inhibition of LincRNA-p21 Protects Against Cardiac Hypertrophy
errCIRCULATION RESEARCH
IF16.2
err2024-07-19
err1
PREAI
errWang, Yi; Zhang, Mingming; Wang, Rong; Lin, Jing; Ma, Qing; Guo, Haipeng; Huang, Huihui; Liang, Zhuomin; Cao, Yangpo; Zhang, Xiaoran; Lu, Yao Wei; Liu, Jianming; Xiao, Feng; Yan, Hualin; Dimitrova, Nadya; Huang, Zhan-Peng; Mably, John D.; Pu, William T.; Wang, Da-Zhi
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Research Directions

No research directions
Co-authors
Cooperation Journals
G
George M. Church
H-index: 190 · Papers: 1.3K
J
Joshua M. Stuart
H-index: 170 · Papers: 578
C
Christine E. Seidman
H-index: 151 · Papers: 708
P
Peter J. Park
H-index: 145 · Papers: 810
D
David Zurakowski
H-index: 134 · Papers: 1.5K
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