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SaveAging and inflammation limit the induction of SARS-CoV-2-specific CD8+T cell responses in severe COVID-19
Autaa, Gaelle; Papagno, Laura; Nogimori, Takuto; Boizard-Moracchini, Andrea; Korenkov, Daniil; Roy, Maeva; Suzuki, Koichiro; Masuta, Yuji; White, Eoghann; Llewellyn-Lacey, Sian; Yoshioka, Yasuo; Nicoli, Francesco; Price, David A.; Dechanet-Merville, Julie; Yamamoto, Takuya; Pellegrin, Isabelle; Appay, Victor
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SaveClonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1
White, Eoghann; Papagno, Laura; Samri, Assia; Sugata, Kenji; Hejblum, Boris; Henry, Amy R.; Rogan, Daniel C.; Darko, Samuel; Recordon-Pinson, Patricia; Dudoit, Yasmine; Llewellyn-Lacey, Sian; Chakrabarti, Lisa A.; Buseyne, Florence; Migueles, Stephen A.; Price, David A.; Andreola, Marie-Aline; Satou, Yorifumi; Thiebaut, Rodolphe; Katlama, Christine; Autran, Brigitte; Douek, Daniel C.; Appay, Victor
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SaveAge differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19
Dallan, Beatrice; Proietto, Davide; De Laurentis, Martina; Gallerani, Eleonora; Martino, Mara; Ghisellini, Sara; Zurlo, Amedeo; Volpato, Stefano; Govoni, Benedetta; Borghesi, Michela; Albanese, Valentina; Appay, Victor; Bonnini, Stefano; Llewellyn-Lacey, Sian; Pacifico, Salvatore; Grumiro, Laura; Brandolini, Martina; Semprini, Simona; Sambri, Vittorio; Ladell, Kristin; Parry, Helen M.; Moss, Paul A. H.; Price, David A.; Caputo, Antonella; Gavioli, Riccardo; Nicoli, Francesco
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SaveImmune response to the recombinant herpes zoster vaccine in people living with HIV over 50 years of age compared to non-HIV age-/gender-matched controls (SHINGR'HIV): a multicenter, international, non-randomized clinical trial study protocol
Hentzien, Maxime; Bonnet, Fabrice; Bernasconi, Enos; Biver, Emmanuel; Braun, Dominique L.; Munting, Aline; Leuzinger, Karoline; Leleux, Olivier; Musardo, Stefano; Prendki, Virginie; Schmid, Patrick; Staehelin, Cornelia; Stoeckle, Marcel; Walti, Carla S.; Wittkop, Linda; Appay, Victor; Didierlaurent, Arnaud M.; Calmy, Alexandra
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SaveHepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8+ T cell quality
Takahama, Shokichi; Yoshio, Sachiyo; Masuta, Yuji; Murakami, Hirotomo; Sakamori, Ryotaro; Kaneko, Shun; Honda, Takashi; Murakawa, Miyako; Sugiyama, Masaya; Kurosaki, Masayuki; Asahina, Yasuhiro; Takehara, Tetsuo; Appay, Victor; Kanto, Tatsuya; Yamamoto, Takuya
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SaveCD8+ T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy
Cabral-Piccin, Mariela P.; Briceno, Olivia; Papagno, Laura; Liouville, Benjamin; White, Eoghann; Perdomo-Celis, Federico; Autaa, Gaelle; Volant, Stevenn; Llewellyn-Lacey, Sian; Fromentin, Remi; Chomont, Nicolas; Price, David A.; Saez-Cirion, Asier; Lambotte, Olivier; Katlama, Christine; Appay, Victor
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SaveMechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis
Guerville, Florent; Vialemaringe, Marine; Cognet, Celine; Duffau, Pierre; Lazaro, Estibaliz; Cazanave, Charles; Bonnet, Fabrice; Leleux, Olivier; Rossignol, Rodrigue; Pinson, Benoit; Tumiotto, Camille; Gabriel, Frederic; Appay, Victor; Dechanet-Merville, Julie; Wittkop, Linda; Faustin, Benjamin; Pellegrin, Isabelle
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SaveAgeing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2
Proietto, Davide; Dallan, Beatrice; Gallerani, Eleonora; Albanese, Valentina; Llewellyn-Lacey, Sian; Price, David A.; Appay, Victor; Pacifico, Salvatore; Caputo, Antonella; Nicoli, Francesco; Gavioli, Riccardo
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SaveA comparison of Sars-Cov-2 vaccine platforms: the CoviCompare project
Molino, Diana; Durier, Christine; Radenne, Anne; Desaint, Corinne; Ropers, Jacques; Courcier, Soizic; Vieillard, Louis Victorien; Rekacewicz, Claire; Parfait, Beatrice; Appay, Victor; Batteux, Frederic; Barillot, Emmanuel; Cogne, Michel; Combadiere, Behazine; Eberhardt, Christiane S.; Gorochov, Guy; Hupe, Philippe; Ninove, Laetitia; Paul, Stephane; Pellegrin, Isabelle; van der Werf, Sylvie; Lefebvre, Maeva; Botelho-Nevers, Elisabeth; Ortega-Perez, Inmaculada; Jaspard, Marie; Sow, Samba; Lelievre, Jean Daniel; de Lamballerie, Xavier; Kieny, Marie Paule; Tartour, Eric; Launay, Odile
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SaveEpitope length variants balance protective immune responses and viral escape in HIV-1 infection
Pymm, Phillip; Tenzer, Stefan; Wee, Edmund; Weimershaus, Mirjana; Burgevin, Anne; Kollnberger, Simon; Gerstoft, Jan; Josephs, Tracy M.; Ladell, Kristin; McLaren, James E.; Appay, Victor; Price, David A.; Fugger, Lars; Bell, John I.; Schild, Hansjoerg; van Endert, Peter; Harkiolaki, Maria; Iversen, Astrid K. N.
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SavePrimary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old
Nicoli, Francesco; Clave, Emmanuel; Wanke, Kerstin; von Braun, Amrei; Bondet, Vincent; Alanio, Cecile; Douay, Corinne; Baque, Margaux; Lependu, Claire; Marconi, Peggy; Stiasny, Karin; Heinz, Franz X.; Muetsch, Margot; Duffy, Darragh; Boddaert, Jacques; Sauce, Delphine; Toubert, Antoine; Karrer, Urs; Appay, Victor
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SaveAltered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans
Nicoli, Francesco; Cabral-Piccin, Mariela P.; Papagno, Laura; Gallerani, Eleonora; Fusaro, Mathieu; Folcher, Victor; Dubois, Marion; Clave, Emmanuel; Vallet, Helene; Frere, Justin J.; Gostick, Emma; Llewellyn-Lacey, Sian; Price, David A.; Toubert, Antoine; Dupre, Loic; Boddaert, Jacques; Caputo, Antonella; Gavioli, Riccardo; Appay, Victor
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