Constance L. Cepko - Publications, H-index & Citations

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Constance L. Cepko

Harvard University

103H-index

336Paper Count

3.8WCitation Count

Published Papers 97

Publication Date

AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage

Molecular Therapy

IF12

2026-03-22

OAAI

Apolonia Gardner; Shuai Wang; Adam Daniels; Dan Li; Christine Wu; Lucas Lin; Christin Hong; Sophia R. Zhao; Richard T. Born; Kamil Kruczek; Genevieve Weist; Laura Barrio Real; Joan Wicks; Mohamad Nayal; Ashley Carter; Christine Ott; Virginia Haurigot; Constance L. Cepko

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AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage

Molecular Therapy

IF12

2026-02-06

OAAI

Apolonia Gardner; Shuai Wang; Adam Daniels; Dan Li; Christine Wu; Lucas Lin; Christin Hong; Sophia R. Zhao; Kamil Kruczek; Genevieve Weist; Laura Barrio Real; Joan Wicks; Mohamad Nayal; Ashley Carter; Christine Ott; Virginia Haurigot; Richard T. Born; Constance L. Cepko

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A Congenic C57BL/6 rd1 Mouse Model for Retinal Degeneration Research

Experimental Eye Research

IF2.7

2025-12-09

OAAI

Laurel C. Chandler; Apolonia Gardner; Constance L. Cepko

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RPE-specific MCT2 expression promotes cone survival in models of retinitis pigmentosa

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-04-03

OAAI

Chandler, Laurel C.; Gardner, Apolonia; Cepko, Constance L.

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ERG responses to high-frequency flickers require FAT3 signaling in mouse retinal bipolar cells

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2025-02-04

OAAI

Aviles, Evelyn C.; Wang, Sean K.; Patel, Sarina; Cordero, Sebastian; Shi, Shuxiang; Lin, Lucas; Kefalov, Vladimir J.; Goodrich, Lisa V.; Cepko, Constance L.; Xue, Yunlu

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Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

ELIFE

IF0

2024-05-10

OAAI

Xue, Yunlu; Zhou, Yimin; Cepko, Constance L.

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Thermal-plex: fluidic-free, rapid sequential multiplexed imaging with DNA-encoded thermal channels

NATURE METHODS

IF32.1

2023-12-27

OAAI

Hong, Fan; Kishi, Jocelyn Y.; Delgado, Ryan N.; Jeong, Jiyoun; Saka, Sinem K.; Su, Hanquan; Cepko, Constance L.; Yin, Peng

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Gene Therapies for Retinitis Pigmentosa that Target Glucose Metabolism

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE

IF10.1

2023-07-17

PREAI

Xue, Yunlu; Cepko, Constance L.

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Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-05-30

OAAI

Xue, Yunlu; Sun, Xiaomei; Wang, Sean K.; Collin, Gayle B.; Kefalov, Vladimir J.; Cepko, Constance L.

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Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

156

OAAI

Bruneau, BG; Bao, ZZ; Fatkin, D; Xavier-Neto, J; Georgakopoulos, D; Maguire, CT; Berul, CI; Kass, DA; Kuroski-de Bold, ML; de Bold, AJ; Conner, DA; Rosenthal, N; Cepko, CL; Seidman, CE; Seidman, JG

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Characterization of mice with targeted deletion of glycine receptor alpha 2

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Young-Pearse, T. L.; Ivic, L.; Kriegstein, A. R.; Cepko, C. L.

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A general approach for stabilizing nanobodies for intracellular expression

ELIFE

IF0

2022-11-23

OAAI

Dingus, John G.; Tang, Jonathan C. Y.; Amamoto, Ryoji; Wallick, Grace K.; Cepko, Constance L.; Luo, Liqun

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Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing

NATURE METHODS

IF32.1

2022-10-10

OAAI

Kishi, Jocelyn Y.; Liu, Ninning; West, Emma R.; Sheng, Kuanwei; Jordanides, Jack J.; Serrata, Matthew; Cepko, Constance L.; Saka, Sinem K.; Yin, Peng

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Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

ELIFE

IF0

2022-03-22

OAAI

Amamoto, Ryoji; Wallick, Grace K.; Cepko, Constance L.

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Targeting Microglia to Treat Degenerative Eye Diseases

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-02-17

OAAI

Wang, Sean K.; Cepko, Constance L.

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Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity

CELL REPORTS

IF6.9

2022-01-01

OAAI

West, Emma R.; Lapan, Sylvain W.; Lee, ChangHee; Kajderowicz, Kathrin M.; Li, Xihao; Cepko, Constance L.

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Augmentation of CD47/SIRPα signaling protects cones in genetic models of retinal degeneration

JCI INSIGHT

IF6.1

2021-08-23

OAAI

Wang, Sean K.; Xue, Yunlu; Cepko, Constance L.

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AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

ELIFE

IF0

2021-04-13

OAAI

Xue, Yunlu; Wang, Sean K.; Rana, Parimal; West, Emma R.; Hong, Christin M.; Feng, Helian; Wu, David M.; Cepko, Constance L.

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Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-02-10

137

OAAI

Chan, Ying Kai; Wang, Sean K.; Chu, Colin J.; Copland, David A.; Letizia, Alexander J.; Verdera, Helena Costa; Chiang, Jessica J.; Sethi, Meher; Wang, May K.; Neidermyer, William J., Jr.; Chan, Yingleong; Lim, Elaine T.; Graveline, Amanda R.; Sanchez, Melinda; Boyd, Ryan F.; Vihtelic, Thomas S.; Inciong, Rolando Gian Carlo O.; Slain, Jared M.; Alphonse, Priscilla J.; Xue, Yunlu; Robinson-McCarthy, Lindsey R.; Tam, Jenny M.; Jabbar, Maha H.; Sahu, Bhubanananda; Adeniran, Janelle F.; Muhuri, Manish; Tai, Phillip W. L.; Xie, Jun; Krause, Tyler B.; Vernet, Andyna; Pezone, Matthew; Xiao, Ru; Liu, Tina; Wang, Wei; Kaplan, Henry J.; Gao, Guangping; Dick, Andrew D.; Mingozzi, Federico; McCall, Maureen A.; Cepko, Constance L.; Church, George M.

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Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa

JCI INSIGHT

IF6.1

2021-01-25

OAAI

Wu, David M.; Ji, Xuke; Ivanchenko, Maryna, V; Chung, Michelle; Piper, Mary; Rana, Parimal; Wang, Sean K.; Xue, Yunlu; West, Emma; Zhao, Sophia R.; Xu, Hongbin; Cicconet, Marcelo; Xiong, Wenjun; Cepko, Constance L.

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Research Directions