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Inflammatory signaling pathways play a role in SYK inhibitor resistant AML Tausch, Sarah; Villinger, Christina; Alexe, Gabriela; Urban, Daniel J.; Shen, Min; Jahn, Dominique; Vischedyk, Jonas; Scheich, Sebastian; Serve, Hubert; Hall, Matthew D.; Stegmaier, Kimberly; Oellerich, Thomas; Cremer, Anjali Share Save
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Posttranslational Changes in Histone Modification Driven By USP48 Loss Increase Sensitivity to Hypomethylating Agents in Acute Myeloid Leukemia Schneider, Constanze; Alexe, Gabriela; Meyer, Ashleigh; Merickel, Lucy A.; Basanthakumar, Allen T.; Taillon, Audrey; Salhotra, Silvi; Rodriguez, Yara; Haeupl, Bjoern; Root, David E.; Oellerich, Thomas; Stegmaier, Kimberly Share Save
Therapeutic targeting of the SAGA KAT module impairs MYCN-amplified neuroblastoma growth through reduction of the MYCN oncogenic gene expression program Mabe, Nathaniel W.; Malone, Clare F.; Forman, Alexandra B.; Alexe, Gabriela; Engel, Kathleen L.; Chen, Ying-Jiun C.; Soeung, Melinda; Salhotra, Silvi; Basanthakumar, Allen; Liu, Bin; Dent, Sharon Y. R.; Stegmaier, Kimberly Share Save
Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia Schneider, Constanze; Spaink, Hermes; Alexe, Gabriela; Dharia, Neekesh V.; Meyer, Ashleigh; Merickel, Lucy A.; Khalid, Delan; Scheich, Sebastian; Haeupl, Bjoern; Staudt, Louis M.; Oellerich, Thomas; Stegmaier, Kimberly Share Save
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma Malone, Clare F.; Mabe, Nathaniel W.; Forman, Alexandra B.; Alexe, Gabriela; Engel, Kathleen L.; Chen, Ying-Jiun C.; Soeung, Melinda; Salhotra, Silvi; Basanthakumar, Allen; Liu, Bin; Dent, Sharon Y. R.; Stegmaier, Kimberly Share Save
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SMARCAL1 is a novel synthetic lethal target in ALT plus osteosarcoma and neuroblastoma Wierdl, Monika; Catlett, Jerrel L.; Ocasio-Martinez, Nicole; Johnson, Jon D.; Herman, Amy; Dharia, Neekesh V.; Alexe, Gabriela; Sweet-Cordero, E. Alejandro; Bernstein, Emily; Stegmaier, Kimberly; Guenther, Lillian M. Share Save
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SMARCAL1 is a selective dependency and a novel synthetic lethal target in ATRX/DAXX mutant ALT plus osteosarcoma and neuroblastoma Wierdl, Monika; Catlett, Jerrel L.; Ocasio-Martinez, Nicole; Johnson, John D.; Herman, Amy; Dharia, Neekesh V.; Alexe, Gabriela; Sweet-Cordero, E. Alejandro; Bernstein, Emily; Stegmaier, Kimberly; Guenther, Lillian M. Share Save
DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia Sexauer, Amy N.; Alexe, Gabriela; Gustafsson, Karin; Zanetakos, Elizabeth; Milosevic, Jelena; Ayres, Mary; Gandhi, Varsha; Pikman, Yana; Stegmaier, Kimberly; Sykes, David B. Share Save
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors Malone, Clare F.; Kim, Minjee; Alexe, Gabriela; Engel, Kathleen; Forman, Alexandra B.; Robichaud, Amanda; Conway, Amy Saur; Goodale, Amy; Meyer, Ashleigh; Khalid, Delan; Thayakumar, Allen; Hatcher, John M.; Gray, Nathanael S.; Piccioni, Federica; Stegmaier, Kimberly Share Save
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1 Mabe, Nathaniel W.; Huang, Min; Dalton, Guillermo N.; Alexe, Gabriela; Schaefer, Daniel A.; Geraghty, Anna C.; Robichaud, Amanda L.; Conway, Amy S.; Khalid, Delan; Mader, Marius M.; Belk, Julia A.; Ross, Kenneth N.; Sheffer, Michal; Linde, Miles H.; Ly, Nghi; Yao, Winnie; Rotiroti, Maria Caterina; Smith, Benjamin A. H.; Wernig, Marius; Bertozzi, Carolyn R.; Monje, Michelle; Mitsiades, Constantine S.; Majeti, Ravindra; Satpathy, Ansuman T.; Stegmaier, Kimberly; Majzner, Robbie G. Share Save
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia Montanaro, Anna; Kitara, Samuel; Cerretani, Elisa; Marchesini, Matteo; Rompietti, Chiara; Pagliaro, Luca; Gherli, Andrea; Su, Angela; Minchillo, Maria Laura; Caputi, Mariafrancesca; Fioretzaki, Rodanthi; Lorusso, Bruno; Ross, Linda; Alexe, Gabriela; Masselli, Elena; Marozzi, Marina; Rizzi, Federica Maria Angela; La Starza, Roberta; Mecucci, Cristina; Xiong, Yan; Jin, Jian; Falco, Angela; Knoechel, Birgit; Aversa, Franco; Candini, Olivia; Quaini, Federico; Sportoletti, Paolo; Stegmaier, Kimberly; Roti, Giovanni Share Save
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia Pardieu, Bryann; Pasanisi, Justine; Ling, Frank; Dal Bello, Reinaldo; Penneroux, Justine; Su, Angela; Joudinaud, Romane; Chat, Laureen; Wu, Hsin Chieh; Duchmann, Matthieu; Sodaro, Gaetano; Chauvel, Clementine; Castelli, Florence A.; Vasseur, Loic; Pacchiardi, Kim; Belloucif, Yannis; Laiguillon, Marie-Charlotte; Meduri, Eshwar; Vaganay, Camille; Alexe, Gabriela; Berrou, Jeannig; Benaksas, Chaima; Forget, Antoine; Braun, Thorsten; Gardin, Claude; Raffoux, Emmanuel; Clappier, Emmanuelle; Ades, Lionel; de The, Hugues; Fenaille, Francois; Huntly, Brian J.; Stegmaier, Kimberly; Dombret, Herve; Fenouille, Nina; Lobry, Camille; Puissant, Alexandre; Itzykson, Raphael Share Save
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