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Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development Mohammed, Abdulvasey; Wang, Wenqing; Arreola, Martin; Solomon, Benjamin D.; Slepicka, Priscila F.; Hubka, Kelsea M.; Nguyen, Hanh Dan; Zheng, Zihao; Chavez, Michael G.; Yeh, Christine Y.; Kim, Doo Kyung; Ma, Michael R.; Martin, Elisabeth; Li, Li; Pasca, Anca M.; Winn, Virginia D.; Gifford, Casey A.; Kedlian, Veronika R.; Park, Jong-Eun; Khatri, Purvesh; Hollander, Georg A.; Roncarolo, Maria Grazia; Sebastiano, Vittorio; Teichmann, Sarah A.; Weinacht, Katja G. Share Save
Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan Wedemeyer, Sarah A.; Jones, Nicholas E.; Raza, Iwan G. A.; Green, Freedom M.; Xiao, Yangming; Semwal, Manpreet K.; Garza, Aaron K.; Archuleta, Kahealani S.; Wimberly, Kymberly L.; Venables, Thomas; Hollander, Georg A.; Griffith, Ann V. Share Save
European Society for Immunodeficiencies guidelines for the management of patients with congenital athymia Kreins, Alexandra Y.; Dhalla, Fatima; Flinn, Aisling M.; Howley, Evey; Ekwall, Olov; Villa, Anna; Staal, Frank J. T.; Anderson, Graham; Gennery, Andrew R.; Hollander, Georg A.; Davies, E. Graham Share Save
Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency Blanco, Elena; Camps, Carme; Bahal, Sameer; Kerai, Mohit D.; Ferla, Matteo P.; Rochussen, Adam M.; Handel, Adam E.; Golwala, Zainab M.; Spiridou Goncalves, Helena; Kricke, Susanne; Klein, Fabian; Zhang, Fang; Zinghirino, Federica; Evans, Grace; Keane, Thomas M.; Lizot, Sabrina; Kusters, Maaike A. A.; Iro, Mildred A.; Patel, Sanjay V.; Morris, Emma C.; Burns, Siobhan O.; Radcliffe, Ruth; Vasudevan, Pradeep; Price, Arthur; Gillham, Olivia; Valdebenito, Gabriel E.; Stewart, Grant S.; Worth, Austen; Adams, Stuart P.; Duchen, Michael; Andre, Isabelle; Adams, David J.; Santili, Giorgia; Gilmour, Kimberly C.; Hollaender, Georg A.; Davies, E. Graham; Taylor, Jenny C.; Griffiths, Gillian M.; Thrasher, Adrian J.; Dhalla, Fatima; Kreins, Alexandra Y. Share Save
Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation Wells, Alexandria C.; Hioki, Kaito A.; Angelou, Constance C.; Lynch, Adam C.; Liang, Xueting; Ryan, Daniel J.; Thesmar, Iris; Zhanybekova, Saule; Zuklys, Saulius; Ullom, Jacob; Cheong, Agnes; Mager, Jesse; Hollander, Georg A.; Pobezinskaya, Elena L.; Pobezinsky, Leonid A. Share Save
Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells Klein, Fabian; Veiga-Villauriz, Clara; Borsch, Anastasiya; Maio, Stefano; Palmer, Sam; Dhalla, Fatima; Handel, Adam E. E.; Zuklys, Saulius; Calvo-Asensio, Irene; Musette, Lucas; Deadman, Mary E. E.; White, Andrea J. J.; Lucas, Beth; Anderson, Graham; Hollander, Georg A. A. Share Save
Embryonic keratin19+ progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla Lucas, Beth; White, Andrea J.; Klein, Fabian; Veiga-Villauriz, Clara; Handel, Adam; Bacon, Andrea; Cosway, Emilie J.; James, Kieran D.; Parnell, Sonia M.; Ohigashi, Izumi; Takahama, Yousuke; Jenkinson, William E.; Hollander, Georg A.; Lu, Wei-Yu; Anderson, Graham Share Save
A circulating subset of iNKT cells mediates antitumor and antiviral immunity Cui, Guangwei; Shimba, Akihiro; Jin, Jianshi; Ogawa, Taisaku; Muramoto, Yukiko; Miyachi, Hitoshi; Abe, Shinya; Asahi, Takuma; Tani-Ichi, Shizue; Dijkstra, Johannes M.; Iwamoto, Yayoi; Kryukov, Kirill; Zhu, Yuanbo; Takami, Daichi; Hara, Takahiro; Kitano, Satsuki; Xu, Yan; Morita, Hajime; Zhang, Moyu; Zreka, Lynn; Miyata, Keishi; Kanaya, Takashi; Okumura, Shinya; Ito, Takashi; Hatano, Etsuro; Takahashi, Yoshimasa; Watarai, Hiroshi; Oike, Yuichi; Imanishi, Tadashi; Ohno, Hiroshi; Ohteki, Toshiaki; Minato, Nagahiro; Kubo, Masato; Hollander, Georg A.; Ueno, Hideki; Noda, Takeshi; Shiroguchi, Katsuyuki; Ikuta, Koichi Share Save
IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4+Foxp3+ regulatory T lymphocytes Apert, Cecile; Galindo-Albarran, Ariel O.; Castan, Sarah; Detraves, Claire; Michaud, Heloise; McJannett, Nicola; Haegeman, Bart; Fillatreau, Simon; Malissen, Bernard; Hollander, Georg; Zuklys, Saulius; Santamaria, Jeremy C.; Joffre, Olivier P.; Romagnoli, Paola; van Meerwijk, Joost P. M. Share Save
Interferon-g resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells Parmigiani, Elena; Ivanek, Robert; Rolando, Chiara; Hafen, Katrin; Turchinovich, Gleb; Lehmann, Frank Michael; Gerber, Alexandra; Brkic, Sime; Frank, Stephan; Meyer, Sara C.; Wakimoto, Hiroaki; Gunel, Murat; Louvi, Angeliki; Mariani, Luigi; Finke, Daniela; Hollaender, Georg; Hutter, Gregor; Tussiwand, Roxane; Taylor, Verdon; Giachino, Claudio Share Save
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Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment Handel, Adam E.; Cheuk, Stanley; Dhalla, Fatima; Maio, Stefano; Huebscher, Tania; Rota, Ioanna; Deadman, Mary E.; Ekwall, Olov; Lutolf, Matthias; Weinberg, Kenneth; Hollaender, Georg Share Save
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency Rota, Ioanna A.; Handel, Adam E.; Maio, Stefano; Klein, Fabian; Dhalla, Fatima; Deadman, Mary E.; Cheuk, Stanley; Newman, Joseph A.; Michaels, Yale S.; Zuklys, Saulius; Prevot, Nicolas; Hublitz, Philip; Charles, Philip D.; Gkazi, Athina Soragia; Adamopoulou, Eleni; Qasim, Waseem; Davies, Edward Graham; Hanson, Imelda; Pagnamenta, Alistair T.; Camps, Carme; Dreau, Helene M.; White, Andrea; James, Kieran; Fischer, Roman; Gileadi, Opher; Taylor, Jenny C.; Fulga, Tudor; Lagerholm, B. Christoffer; Anderson, Graham; Sezgin, Erdinc; Hollaender, Georg A. Share Save
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Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor κB kinase alpha (IKKα) Bainter, Wayne; Lougaris, Vassilios; Wallace, Jacqueline G.; Badran, Yousef; Hoyos-Bachiloglu, Rodrigo; Peters, Zachary; Wilkie, Hazel; Das, Mrinmoy; Janssen, Erin; Beano, Abdallah; Ben Farhat, Khaoula; Kam, Christy; Bercich, Luisa; Incardona, Paolo; Villanacci, Vincenzo; Bondioni, Maria Pia; Meini, Antonella; Baronio, Manuela; Abarzua, Phammela; Parolini, Silvia; Tabellini, Giovanna; Maio, Stefano; Schmidt, Birgitta; Goldsmith, Jeffrey D.; Murphy, George; Hollander, Georg; Plebani, Alessandro; Chou, Janet; Geha, Raif S. Share Save
Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2 Barthlott, Thomas; Handel, Adam E.; Teh, Hong Ying; Wirasinha, Rushika C.; Hafen, Katrin; Zuklys, Saulius; Roch, Benoit; Orkin, Stuart H.; de Villartay, Jean-Pierre; Daley, Stephen R.; Hollaender, Georg A. Share Save
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function Oftedal, Bergithe E.; Maio, Stefano; Handel, Adam E.; White, Madeleine P. J.; Howie, Duncan; Davis, Simon; Prevot, Nicolas; Rota, Ioanna A.; Deadman, Mary E.; Kessler, Benedikt M.; Fischer, Roman; Trede, Nikolaus S.; Sezgin, Erdinc; Maizels, Rick M.; Hollander, Georg A. Share Save
Thymus Extracellular Matrix-Derived Scaffolds Support Graft-Resident Thymopoiesis and Long-Term In Vitro Culture of Adult Thymic Epithelial Cells Asnaghi, M. Adelaide; Barthlott, Thomas; Gullotta, Fabiana; Strusi, Valentina; Amovilli, Anna; Hafen, Katrin; Srivastava, Gitika; Oertle, Philipp; Toni, Roberto; Wendt, David; Hollaender, Georg A.; Martin, Ivan Share Save
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