Not logged in Challenging the Undruggable-Targeting STAT3 but Identifying Potent TrkA-Targeted Inhibitors Iliev, Petar; Mccutcheon, Conall; Admas, Tizita H.; Reithmeier, Anja; McDonald, Melanie Lopez; van Outryve, Alexandre; Hanke, Danielle; Brown, Jennifer I.; Haraldsson, Martin; Toillon, Robert-Alain; Frank, David A. Share Save
Proteomics profiling of inflammatory responses to elexacaftor/tezacaftor/ivacaftor in cystic fibrosis Ozuna, Hazel; Bojja, Dinesh; Partida-Sanchez, Santiago; Hall-Stoodley, Luanne; Amer, Amal; Britt Jr, Rodney D.; Sheikh, Shahid; Frank, David A.; Wang, Weiyuan; Kang, Bum-Yong; Miralda, Irina; Durfey, Samantha L.; Kopp, Benjamin T. Share Save
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Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens Brown, Jennifer I.; Persaud, Rosanne; Iliev, Petar; Karmacharya, Ujjwala; Attarha, Sanaz; Sahile, Henok; Olsen, Jonas E.; Hanke, Danielle; Idowu, Temilolu; Frank, David A.; Frankel, Adam; Williams, Karla C.; Page, Brent D. G. Share Save
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Prolactin levels and breast cancer risk by tumor expression of prolactin-related markers Hathaway, Cassandra A.; Rice, Megan S.; Collins, Laura C.; Chen, Dilys; Frank, David A.; Walker, Sarah; Clevenger, Charles V.; Tamimi, Rulla M.; Tworoger, Shelley S.; Hankinson, Susan E. Share Save
Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity Brown, Jennifer I. I.; Wang, Peng; Wong, Alan Y. L.; Petrova, Boryana; Persaud, Rosanne; Soukhtehzari, Sepideh; McDonald, Melanie Lopez; Hanke, Danielle; Christensen, Josephine; Iliev, Petar; Wang, Weiyuan; Everton, Daniel K. K.; Williams, Karla C. C.; Frank, David A. A.; Kanarek, Naama; Page, Brent D. G. Share Save
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States Stevens, Laura E.; Peluffo, Guillermo; Qiu, Xintao; Temko, Daniel; Fassl, Anne; Li, Zheqi; Trinh, Anne; Seehawer, Marco; Jovanovic, Bojana; Aleckovic, Masa; Wilde, Callahan M.; Geck, Renee C.; Shu, Shaokun; Kingston, Natalie L.; Harper, Nicholas W.; Almendro, Vanessa; Pyke, Alanna L.; Egri, Shawn B.; Papanastasiou, Malvina; Clement, Kendell; Zhou, Ningxuan; Walker, Sarah; Salas, Jacqueline; Park, So Yeon; Frank, David A.; Meissner, Alexander; Jaffe, Jacob D.; Sicinski, Piotr; Toker, Alex; Michor, Franziska; Long, Henry W.; Overmoyer, Beth A.; Polyak, Kornelia Share Save
Increased MYBL2 expression in aggressive hormone-sensitive prostate cancer Yoshikawa, Yuki; Stopsack, Konrad H.; Wang, Xin Victoria; Chen, Yu-Hui; Mazzu, Ying Z.; Burton, Foster; Chakraborty, Goutam; Rajanala, Sai Harisha; Hirani, Rahim; Nandakumar, Subhiksha; Lee, Gwo-Shu Mary; Frank, David; Davicioni, Elai; Liu, Glenn; Carducci, Michael A.; Azuma, Haruhito; Kantoff, Philip W.; Sweeney, Christopher J. Share Save
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Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration Ajay, Amrendra K.; Zhao, Li; Vig, Shruti; Fujiwara, Mai; Thakurela, Sudhir; Jadhav, Shreyas; Cho, Andrew; I-Jen Chiu; Ding, Yan; Ramachandran, Krithika; Mithal, Arushi; Bhatt, Aanal; Chaluvadi, Pratyusha; Gupta, Manoj K.; Shah, Sujal, I; Sabbisetti, Venkata S.; Waaga-Gasser, Ana Maria; Frank, David A.; Murugaiyan, Gopal; Bonventre, Joseph, V; Li-Li Hsiao Share Save
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase Heppler, Lisa N.; Attarha, Sanaz; Persaud, Rosanne; Brown, Jennifer, I; Wang, Peng; Petrova, Boryana; Tosic, Isidora; Burton, Foster B.; Flamand, Yael; Walker, Sarah R.; Yeh, Jennifer E.; Zubarev, Roman A.; Gaetani, Massimiliano; Kanarek, Naama; Page, Brent D. G.; Frank, David A. Share Save
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IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca2+through the noncanonical STAT3 pathway Valenca-Pereira, Felipe; Fang, Qian; Marie, Isabelle J.; Giddings, Emily L.; Fortner, Karen A.; Yang, Rui; Villarino, Alejandro V.; Huang, Yina H.; Frank, David A.; Wen, Haitao; Levy, David E.; Rincon, Mercedes Share Save
Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM) Lapidot, Moshe; Case, Abigail E.; Weisberg, Ellen L.; Meng, Chengcheng; Walker, Sarah R.; Garg, Swati; Ni, Wei; Podar, Klaus; Hung, Yin P.; Carrasco, Ruben D.; Knott, Aine; Gokhale, Prafulla C.; Sharma, Sunil; Pozhitkov, Alex; Kulkarni, Prakash; Frank, David A.; Salgia, Ravi; Griffin, James D.; Saladi, Srinivas V.; Bueno, Raphael; Sattler, Martin Share Save
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