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Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway Hodson, David; Mistry, Hitesh; Guzzetti, Sofia; Davies, Michael; Staniszewska, Anna; Farrington, Paul; Cadogan, Elaine; Yates, James; Aarons, Leon; Ogungbenro, Kayode Share Save
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future Darwich, A. S.; Ogungbenro, K.; Vinks, A. A.; Powell, J. R.; Reny, J-L; Marsousi, N.; Daali, Y.; Fairman, D.; Cook, J.; Lesko, L. J.; McCune, J. S.; Knibbe, C. A. J.; de Wildt, S. N.; Leeder, J. S.; Neely, M.; Zuppa, A. F.; Vicini, P.; Aarons, L.; Johnson, T. N.; Boiani, J.; Rostami-Hodjegan, A. Share Save
IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds Margolskee, Alison; Darwich, Adam S.; Pepin, Xavier; Pathak, Shriram M.; Bolger, Michael B.; Aarons, Leon; Rostami-Hodjegan, Amin; Angstenberger, Jonas; Graf, Franziska; Laplanche, Loic; Mueller, Thomas; Carlert, Sara; Daga, Pankaj; Murphy, Donal; Tannergren, Christer; Yasin, Mohammed; Greschat-Schade, Susanne; Mueck, Wolfgang; Muenster, Uwe; van der Mey, Dorina; Frank, Kerstin Julia; Lloyd, Richard; Adriaenssen, Lieve; Bevernage, Jan; De Zwart, Loeckie; Swerts, Dominique; Tistaert, Christophe; Van Den Bergh, An; Van Peer, Achiel; Beato, Stefania; Anh-Thu Nguyen-Trung; Bennett, Joanne; McAllister, Mark; Wong, Mei; Zane, Patricia; Ollier, Celine; Vicat, Pascale; Kolhmann, Markus; Marker, Alexander; Brun, Priscilla; Mazuir, Florent; Beilles, Stephane; Venczel, Marta; Boulenc, Xavier; Loos, Petra; Lennernas, Hans; Abrahamsson, Bertil Share Save
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes Darwich, Adam S.; Margolskee, Alison; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmann, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil Share Save
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results Margolskee, Alison; Darwich, Adam S.; Pepin, Xavier; Aarons, Leon; Galetin, Aleksandra; Rostami-Hodjegan, Amin; Carlert, Sara; Hammarberg, Maria; Hilgendorf, Constanze; Johansson, Pernilla; Karlsson, Eva; Murphy, Donal; Tannergren, Christer; Thorn, Helena; Yasin, Mohammed; Mazuir, Florent; Nicolas, Olivier; Ramusovic, Sergej; Xu, Christine; Pathak, Shriram M.; Korjamo, Timo; Laru, Johanna; Malkki, Jussi; Pappinen, Sari; Tuunainen, Johanna; Dressman, Jennifer; Hansmanni, Simone; Kostewicz, Edmund; He, Handan; Heimbach, Tycho; Wu, Fan; Hoft, Carolin; Laplanche, Loic; Pang, Yan; Bolger, Michael B.; Huehn, Eva; Lukacova, Viera; Mullin, James M.; Szeto, Ke X.; Costales, Chester; Lin, Jian; McAllister, Mark; Modi, Sweta; Rotter, Charles; Varma, Manthena; Wong, Mei; Mitra, Amitava; Bevernage, Jan; Biewenga, Jeike; Van Peer, Achiel; Lloyd, Richard; Shardlow, Carole; Langguth, Peter; Mishenzon, Irina; Mai Anh Nguyen; Brown, Jonathan; Lennernas, Hans; Abrahamsson, Bertil Share Save
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