Laurence D. Hurst - Publications, H-index & Citations

Laurence D. Hurst

university of bath

85H指数

414论文数

2.8W被引数

收录论文 177

发表时间

Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk 内源性逆转录病毒元件LTR8B和MER65重编程PSG9调控以控制滋养层细胞融合和子痫前期风险

Genome Biology

IF9.4

2026-03-09

OAAI

Manvendra Singh; Yuliang Qu; Amit Pande; Julianna Zadora; Florian Herse; Martin Gauster; Xuhui Kong; Rongyan Zheng; Rabia Anwar; Katarina Stevanovic; Ralf Dechend; Marie Cohen; Attila Molvarec; Jichang Wang; Miriam K. Konkel; Bin Zhang; Cedric Feschotte; Gabriela Dveksler; Sandra M. Blois; Laurence D. Hurst; Zsuzsanna Izsvák

Bacterial gene 5′ ends have unusual mutation rates that can mislead tests of selection 细菌基因5′端具有异常的突变率，这可能误导选择测试。

PLOS Biology

IF7.2

2025-12-15

PREAI

Radrizzani, Sofia; Rivas-Santisteban, Juan; Han, Namshik; Hurst, Laurence D.

ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia ERV3-MLT1为人胎盘功能提供顺式调控元件，并且通常在人类特有子痫前期中发生失调。

Genome Biology

IF9.4

2025-11-06

OAAI

Rabia Anwar; Amit Pande; Manvendra Singh; Zhi Huang; Eve Hallett; Yiran Xie; Alexandra Gellhaus; Florian Herse; Olivia Nonn; Martin Gauster; Tamás Raskó; Matthias Selbach; Stefan Verlohren; Anne Cathrine Staff; Ralf Dechend; Ulrich Pecks; Sandra M. Blois; Laurence D. Hurst; Zsuzsanna Izsvák

Cell Compartment is a Predictor of Protein Rate of Evolution, but not in the Manner Expected: Evidence Against the Extended Complexity Hypothesis 细胞区室是蛋白质进化速率的预测因子，但并非以预期的方式：对扩展复杂性假说的证据反对

GENOME BIOLOGY AND EVOLUTION

IF2.8

2025-07-01

OAAI

Rivas-Santisteban, Juan; Yubero, Pablo; Hurst, Laurence D.

Why AGG is associated with high transgene output: passenger effects and their implications for transgene design AGG为何与高外源基因表达量相关：伴随效应及其对外源基因设计的启示

NAR GENOMICS AND BIOINFORMATICS

IF2.8

2025-06-01

OAAI

Daniels, Kate G.; Radrizzani, Sofia; Hurst, Laurence D.

RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats RID对于重复诱导的点突变以及异染色质状态的新型过渡性核化过程中的常染色质重复序列是必需的。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-04-04

OAAI

He, Zhen; Wu, Nannan; Yao, Ruonan; Tan, Huawei; Sun, Yingying; Chen, Jingxuan; Xue, Lan; Chen, Xiaonan; Yang, Sihai; Hurst, Laurence D.; Wang, Long; Huang, Ju

Epistasis, core-genome disharmony, and adaptation in recombining bacteria

MBIO

IF4.7

2024-06-12

OAAI

Taylor, Aidan J.; Yahara, Koji; Pascoe, Ben; Ko, Seungwon; Mageiros, Leonardos; Mourkas, Evangelos; Calland, Jessica K.; Puranen, Santeri; Hitchings, Matthew D.; Jolley, Keith A.; Kobras, Carolin M.; Bayliss, Sion; Williams, Nicola J.; van Vliet, Arnoud H. M.; Parkhill, Julian; Maiden, Martin C. J.; Corander, Jukka; Hurst, Laurence D.; Falush, Daniel; Keim, Paul; Didelot, Xavier; Kelly, David J.; Sheppard, Samuel K.

Selection on synonymous sites: the unwanted transcript hypothesis

NATURE REVIEWS GENETICS

IF52

2024-01-31

PREAI

Radrizzani, Sofia; Kudla, Grzegorz; Izsvak, Zsuzsanna; Hurst, Laurence D.

Genes for highly abundant proteins in Escherichia coli avoid 5' codons that promote ribosomal initiation

plos biology

IF3.6

2023-10-25

OAAI

Lewin, Loveday E.; Daniels, Kate G.; Hurst, Laurence D.

Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-07-17

OAAI

Singh, Manvendra; Kondraskhina, Aleksandra M.; Hurst, Laurence D.; Izsvak, Zsuzsanna

Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters

GENOME BIOLOGY

IF9.4

2023-03-03

OAAI

Richer, Stephen; Tian, Yuan; Schoenfelder, Stefan; Hurst, Laurence; Murrell, Adele; Pisignano, Giuseppina

A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2022-08-23

OAAI

Rasko, Tamas; Pande, Amit; Radscheit, Kathrin; Zink, Annika; Singh, Manvendra; Sommer, Christian; Wachtl, Gerda; Kolacsek, Orsolya; Inak, Gizem; Szvetnik, Attila; Petrakis, Spyros; Bunse, Mario; Bansal, Vikas; Selbach, Matthias; Orban, Tamas, I; Prigione, Alessandro; Hurst, Laurence D.; Izsvak, Zsuzsanna

Stop Codon Usage as a Window into Genome Evolution: Mutation, Selection, Biased Gene Conversion and the TAG Paradox 终止密码子使用作为基因组进化的窗口: 突变，选择，偏向基因转换和标签悖论

GENOME BIOLOGY AND EVOLUTION

IF2.8

2022-07-22

OAAI

Ho, Alexander T.; Hurst, Laurence D.

Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development

CELL STEM CELL

IF20.4

2022-07-01

OAAI

Yu, Hanwen; Chen, Manqi; Hu, Yuanlang; Ou, Songbang; Yu, Xiu; Liang, Shiqi; Li, Niannian; Yang, Mingzhu; Kong, Xuhui; Sun, Chuanbo; Jia, Shiqi; Zhang, Qingxue; Liu, Lin; Hurst, Laurence D.; Li, Ruiqi; Wang, Wenjun; Wang, Jichang

In rice splice variants that restore the reading frame after frameshifting indel introduction are common, often induced by the indels and sometimes lead to organism-level rescue 在水稻中，在移码indel引入后恢复阅读框的剪接变体很常见，通常由indel诱导，有时导致生物体水平的拯救

PLOS GENETICS

IF3.7

2022-02-18

OAAI

Jia, Yanxiao; Qin, Chao; Traw, Milton Brian; Chen, Xiaonan; He, Ying; Kai, Jing; Yang, Sihai; Wang, Long; Hurst, Laurence D.

Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes 来自果蝇的证据支持更快进化基因的更高复制性

GENOME BIOLOGY AND EVOLUTION

IF2.8

2022-01-09

OAAI

Vance, Zoe; Niezabitowski, Lukasz; Hurst, Laurence D.; McLysaght, Aoife

Variation in Release Factor Abundance Is Not Needed to Explain Trends in Bacterial Stop Codon Usage

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2021-11-09

OAAI

Ho, Alexander T.; Hurst, Laurence D.

Evidence for Strong Mutation Bias toward, and Selection against, U Content in SARS-CoV-2: Implications for Vaccine Design (vol 38, pg 67, 2021)

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2021-09-14

OAAI

Rice, Alan M.; Morales, Atahualpa Castillo; Ho, Alexander T.; Mordstein, Christine; Muehlhausen, Stefanie; Watson, Samir; Cano, Laura; Young, Bethan; Kudla, Grzegorz; Hurst, Laurence D.

Evidence in disease and non-disease contexts that nonsense mutations cause altered splicing via motif disruption

NUCLEIC ACIDS RESEARCH

IF13.1

2021-09-01

OAAI

Abrahams, Liam; Savisaar, Rosina; Mordstein, Christine; Young, Bethan; Kudla, Grzegorz; Hurst, Laurence D.

Causes and Consequences of Purifying Selection on SARS-CoV-2

GENOME BIOLOGY AND EVOLUTION

IF2.8

2021-08-24

OAAI

Morales, Atahualpa Castillo; Rice, Alan M.; Ho, Alexander T.; Mordstein, Christine; Muhlhausen, Stefanie; Watson, Samir; Cano, Laura; Young, Bethan; Kudla, Grzegorz; Hurst, Laurence D.

研究方向