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M

Michelle Debatisse

Gustave Roussy Institute
H指数:41
被引数:6,448

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RAD51 up- or down regulation is highly toxic to human transformed cells through the induction of replication stress, G2/M arrest and apoptosis

RAD51的上调或下调通过诱导复制应激、G2/M期阻滞和凋亡对人类转化细胞具有高度毒性

Cell Death & Disease
IF9.6
2026-10-130
OAAI
Melissa Thomas; Alessandra Poma; Nine le Dilly; Elodie Dardillac; Stéphane Koundrioukoff; Quentin Delacour; Jean-Philippe Morretton; Ayeong So; Michelle Debatisse; Olivier Gavet; Jean-Yves Masson; Bernard Lopez; Josée Guirouilh-Barbat
ATR and TopBP1 oppose to control dormant origin activity and global replication dynamics, providing a first defense against replication stress

ATR和TopBP1通过控制休眠起源活性和全局复制动力学，提供对抗复制应激的第一道防线

Nucleic Acids Research
IF13.1
2026-04-210
OA
Stéphane Koundrioukoff; Nathan Alary; Su-Jung Kim; Thibault Collin; Antoine Toffano; Rodrigo Melendez-Garcia; Xia Wu; Yaqun Liu; Stefano Gnan; Sami El-Hilali; Olivier Brison; Filippo Rosselli; Chun-Long Chen; Michelle Debatisse; null
In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis

体内减少RAD51-mediated同源重组会触发衰老，但会损害肿瘤发生

EMBO JOURNAL
IF8.3
2023-09-044
OAAI
Matos-Rodrigues, Gabriel; Barroca, Vilma; Muhammad, Ali-Akbar; Dardillac, Elodie; Allouch, Awatef; Koundrioukoff, Stephane; Lewandowski, Daniel; Despras, Emmanuelle; Guirouilh-Barbat, Josee; Frappart, Lucien; Kannouche, Patricia; Dupaigne, Pauline; Le Cam, Eric; Perfettini, Jean-Luc; Romeo, Paul-Henri; Debatisse, Michelle; Jasin, Maria; Livera, Gabriel; Martini, Emmanuelle; Lopez, Bernard S.
Transcription-mediated organization of the replication initiation program across large genes sets common fragile sites genome-wide

跨大基因的复制起始程序的转录介导的组织在全基因组范围内设置常见的脆弱位点

NATURE COMMUNICATIONS
IF15.7
2019-12-1369
OAAI
Brison, Olivier; El-Hilali, Sami; Azar, Dana; Koundrioukoff, Stephane; Schmidt, Melanie; Nahse, Viola; Jaszczyszyn, Yan; Lachages, Anne-Marie; Dutrillaux, Bernard; Thermes, Claude; Debatisse, Michelle; Chen, Chun-Long
TIPIN depletion leads to apoptosis in breast cancer cells
MOLECULAR ONCOLOGY
IF4.5
2015-05-0916
OAAI
Baldeyron, Celine; Brisson, Amelie; Tesson, Bruno; Nemati, Fariba; Koundrioukoff, Stephane; Saliba, Elie; De Koning, Leanne; Martel, Elise; Ye, Mengliang; Rigaill, Guillem; Meseure, Didier; Nicolas, Andre; Gentien, David; Decaudin, Didier; Debatisse, Michelle; Depil, Stephane; Cruzalegui, Francisco; Pierre, Alain; Roman-Roman, Sergio; Tucker, Gordon C.; Dubois, Thierry

研究方向

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S
Stéphane Koundrioukoff
H 指数:19论文数:34被引数:2,263
O
Olivier Brison
H 指数:35论文数:109被引数:4,263
B
Bernard Dutrillaux
H 指数:66论文数:532被引数:1.6万
B
Benoît Le Tallec
H 指数:14论文数:26被引数:1,497
B
Bernard S. López
H 指数:48论文数:270被引数:7,715
A
Anne-Marie Lachagès
H 指数:12论文数:15被引数:1,073
H
Hervé Técher
H 指数:11论文数:22被引数:1,845
T
Therese Wilhelm
H 指数:13论文数:24被引数:1,266
N
Nicolas Vogt
H 指数:22论文数:74被引数:1,697
G
Gaël A. Millot
H 指数:25论文数:68被引数:2,646