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Alexander Hillisch

ucb biosciences gmbh

31H指数
96论文数
4.0K被引数
收录论文 35
发表时间
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CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2缓存挑战 #3: 以SARS-CoV-2的Nsp3宏域为目标
errJournal of Chemical Information and Modeling
IF5.3
err2026-01-21
err0
errOAAI
errOleksandra Herasymenko; Madhushika Silva; Galen J. Correy; Abd Al-Aziz A. Abu-Saleh; Suzanne Ackloo; Cheryl Arrowsmith; Alan Ashworth; Fuqiang Ban; Hartmut Beck; Kevin P. Bishop; Hugo J. Bohórquez; Albina Bolotokova; Marko Breznik; Irene Chau; Yu Chen; Artem Cherkasov; Wim Dehaen; Dennis Della Corte; Katrin Denzinger; Niklas P. Doering; Kristina Edfeldt; Aled Edwards; Darren Fayne; Francesco Gentile; Elisa Gibson; Ozan Gokdemir; Anders Gunnarsson; Judith Günther; John J. Irwin; Jan Halborg Jensen; Rachel J. Harding; Alexander Hillisch; Laurent Hoffer; Anders Hogner; Ashley Hutchinson; Shubhangi Kandwal; Andrea Karlova; Kushal Koirala; Sergei Kotelnikov; Dima Kozakov; Juyong Lee; Soowon Lee; Uta Lessel; Sijie Liu; Xuefeng Liu; Peter Loppnau; Jens Meiler; Rocco Moretti; Yurii S. Moroz; Charuvaka Muvva; Tudor I. Oprea; Brooks Paige; Amit Pandit; Keunwan Park; Gennady Poda; Mykola V. Protopopov; Vera Pütter; Rahul Ravichandran; Didier Rognan; Edina Rosta; Yogesh Sabnis; Thomas Scott; Almagul Seitova; Purshotam Sharma; François Sindt; Minghu Song; Casper Steinmann; Rick Stevens; Valerij Talagayev; Valentyna V. Tararina; Olga Tarkhanova; Damon Tingey; John F. Trant; Dakota Treleaven; Alexander Tropsha; Patrick Walters; Jude Wells; Yvonne Westermaier; Gerhard Wolber; Lars Wortmann; Shuangjia Zheng; James S. Fraser; Matthieu Schapira
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CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13CACHE挑战赛#2：靶向SARS-CoV-2解旋酶Nsp13的RNA位点
errJournal of Chemical Information and Modeling
IF5.3
err2025-06-20
err0
PREAI
errOleksandra Herasymenko; Madhushika Silva; Abd Al-Aziz A. Abu-Saleh; Ayaz Ahmad; Jesus Alvarado-Huayhuaz; Oscar E. A. Arce; Roly J. Armstrong; Cheryl Arrowsmith; Kelly E. Bachta; Hartmut Beck; Denes Berta; Mateusz K. Bieniek; Vincent Blay; Albina Bolotokova; Philip E. Bourne; Marko Breznik; Peter J. Brown; Aaron D. G. Campbell; Emanuele Carosati; Irene Chau; Daniel J. Cole; Ben Cree; Wim Dehaen; Katrin Denzinger; Karina dos Santos Machado; Ian Dunn; Prasannavenkatesh Durai; Kristina Edfeldt; Aled Edwards; Darren Fayne; Daniel Felfoldi; Kallie Friston; Pegah Ghiabi; Elisa Gibson; Judith Günther; Anders Gunnarsson; Alexander Hillisch; Douglas R. Houston; Jan Halborg Jensen; Rachel J. Harding; Kate S. Harris; Laurent Hoffer; Anders Hogner; Joshua T. Horton; Scott Houliston; Judd F. Hultquist; Ashley Hutchinson; John J. Irwin; Marko Jukič; Shubhangi Kandwal; Andrea Karlova; Vittorio L. Katis; Ryan P. Kich; Dmitri Kireev; David Koes; Nicole L. Inniss; Uta Lessel; Sijie Liu; Peter Loppnau; Wei Lu; Sam Martino; Miles McGibbon; Jens Meiler; Akhila Mettu; Sam Money-Kyrle; Rocco Moretti; Yurii S. Moroz; Charuvaka Muvva; Joseph A. Newman; Leon Obendorf; Brooks Paige; Amit Pandit; Keunwan Park; Sumera Perveen; Rachael Pirie; Gennady Poda; Mykola Protopopov; Vera Pütter; Federico Ricci; Natalie J. Roper; Edina Rosta; Margarita Rzhetskaya; Yogesh Sabnis; Karla J. F. Satchell; Frederico Schmitt Kremer; Thomas Scott; Almagul Seitova; Casper Steinmann; Valerij Talagayev; Olga O. Tarkhanova; Natalie J. Tatum; Dakota Treleaven; Adriano Velasque Werhli; W. Patrick Walters; Xiaowen Wang; Jude Wells; Geoffrey Wells; Yvonne Westermaier; Gerhard Wolber; Lars Wortmann; Jixian Zhang; Zheng Zhao; Shuangjia Zheng; Matthieu Schapira
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CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-11-05
err4
errOAAI
errLi, Fengling; Ackloo, Suzanne; Arrowsmith, Cheryl H.; Ban, Fuqiang; Barden, Christopher J.; Beck, Hartmut; Beranek, Jan; Berenger, Francois; Bolotokova, Albina; Bret, Guillaume; Breznik, Marko; Carosati, Emanuele; Chau, Irene; Chen, Yu; Cherkasov, Artem; Della Corte, Dennis; Denzinger, Katrin; Dong, Aiping; Draga, Sorin; Dunn, Ian; Edfeldt, Kristina; Edwards, Aled; Eguida, Merveille; Eisenhuth, Paul; Friedrich, Lukas; Fuerll, Alexander; Gardiner, Spencer S.; Gentile, Francesco; Ghiabi, Pegah; Gibson, Elisa; Glavatskikh, Marta; Gorgulla, Christoph; Guenther, Judith; Gunnarsson, Anders; Gusev, Filipp; Gutkin, Evgeny; Halabelian, Levon; Harding, Rachel J.; Hillisch, Alexander; Hoffer, Laurent; Hogner, Anders; Houliston, Scott; Irwin, John J.; Isayev, Olexandr; Ivanova, Aleksandra; Jacquemard, Celien; Jarrett, Austin J.; Jensen, Jan H.; Kireev, Dmitri; Kleber, Julian; Koby, S. Benjamin; Koes, David; Kumar, Ashutosh; Kurnikova, Maria G.; Kutlushina, Alina; Lessel, Uta; Liessmann, Fabian; Liu, Sijie; Lu, Wei; Meiler, Jens; Mettu, Akhila; Minibaeva, Guzel; Moretti, Rocco; Morris, Connor J.; Narangoda, Chamali; Noonan, Theresa; Obendorf, Leon; Pach, Szymon; Pandit, Amit; Perveen, Sumera; Poda, Gennady; Polishchuk, Pavel; Puls, Kristina; Puetter, Vera; Rognan, Didier; Roskams-Edris, Dylan; Schindler, Christina; Sindt, Francois; Spiwok, Vojtech; Steinmann, Casper; Stevens, Rick L.; Talagayev, Valerij; Tingey, Damon; Vu, Oanh; Walters, W. Patrick; Wang, Xiaowen; Wang, Zhenyu; Wolber, Gerhard; Wolf, Clemens Alexander; Wortmann, Lars; Zeng, Hong; Zepeda, Carlos A.; Zhang, Kam Y. J.; Zhang, Jixian; Zheng, Shuangjia; Schapira, Matthieu
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Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-06-19
err1
PREAI
errMittal, Anshumali; Martin, Matthew F.; Levin, Elena J.; Adams, Christopher; Yang, Meng; Provins, Laurent; Hall, Adrian; Procter, Martin; Ledecq, Marie; Hillisch, Alexander; Wolff, Christian; Gillard, Michel; Horanyi, Peter S.; Coleman, Jonathan A.
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Design and Preclinical Characterization Program toward Asundexian (BAY 2433334), an Oral Factor XIa Inhibitor for the Prevention and Treatment of Thromboembolic Disorders
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-09-05
err11
errOAAI
errRoehrig, Susanne; Ackerstaff, Jens; Nunez, Eloiisa Jimenez; Teller, Henrik; Ellerbrock, Pascal; Meier, Katharina; Heitmeier, Stefan; Tersteegen, Adrian; Stampfuss, Jan; Lang, Dieter; Schlemmer, Karl-Heinz; Schaefer, Martina; Gericke, Kersten M.; Kinzel, Tom; Meibom, Daniel; Schmidt, Martina; Gerdes, Christoph; Follmann, Markus; Hillisch, Alexander
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Target 2035-an update on private sector contributions
errRSC MEDICINAL CHEMISTRY
IF3.6
err2023-01-01
err5
errOAAI
errAckloo, Suzanne; Antolin, Albert A.; Bartolome, Jose Manuel; Beck, Hartmut; Bullock, Alex; Betz, Ulrich A. K.; Boettcher, Jark.; Brown, Peter J.; Chaturvedi, Menorca; Crisp, Alisa; Daniels, Danette; Dreher, Jan; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Elkins, Jon; Fischer, Christian; Glendorf, Tine; Goldberg, Steven; Hartung, Ingo V.; Hillisch, Alexander; Homan, Evert; Knapp, Stefan; Koester, Markus; Kraemer, Oliver; Llaveria, Josep; Lessel, Uta; Lindemann, Sven; Linderoth, Lars; Matsui, Hisanori; Michel, Maurice; Montel, Florian; Mueller-Fahrnow, Anke; Mueller, Susanne; Owen, Dafydd R.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Sanderson, Wendy; Scholten, Cora; Schapira, Matthieu; Sharma, Sujata; Shireman, Brock; Sundstrom, Michael; Todd, Matthew H.; Tredup, Claudia; Venable, Jennifer; Willson, Timothy M.; Arrowsmith, Cheryl H.
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Cyclobutane-bearing restricted anchoring residues enabled geometry-specific hydrocarbon peptide stapling
errCHEMICAL SCIENCE
IF7.4
err2023-01-01
err6
errOAAI
errChen, Baobao; Liu, Chao; Cong, Wei; Gao, Fei; Zou, Yan; Su, Li; Liu, Lei; Hillisch, Alexander; Lehmann, Lutz; Bierer, Donald; Li, Xiang; Hu, Hong-Gang
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err收藏
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-findingCACHE (计算命中发现实验的关键评估): 一项公私合作伙伴关系基准计划，旨在开发命中发现的计算方法
errNATURE REVIEWS CHEMISTRY
IF51.7
err2022-02-15
err38
errOAAI
errAckloo, Suzanne; Al-awar, Rima; Amaro, Rommie E.; Arrowsmith, Cheryl H.; Azevedo, Hatylas; Batey, Robert A.; Bengio, Yoshua; Betz, Ulrich A. K.; Bologa, Cristian G.; Chodera, John D.; Cornell, Wendy D.; Dunham, Ian; Ecker, Gerhard F.; Edfeldt, Kristina; Edwards, Aled M.; Gilson, Michael K.; Gordijo, Claudia R.; Hessler, Gerhard; Hillisch, Alexander; Hogner, Anders; Irwin, John J.; Jansen, Johanna M.; Kuhn, Daniel; Leach, Andrew R.; Lee, Alpha A.; Lessel, Uta; Morgan, Maxwell R.; Moult, John; Muegge, Ingo; Oprea, Tudor, I; Perry, Benjamin G.; Riley, Patrick; Rousseaux, Sophie A. L.; Saikatendu, Kumar Singh; Santhakumar, Vijayaratnam; Schapira, Matthieu; Scholten, Cora; Todd, Matthew H.; Vedadi, Masoud; Volkamer, Andrea; Willson, Timothy M.
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Target 2035-update on the quest for a probe for every protein
errRSC MEDICINAL CHEMISTRY
IF3.6
err2022-01-01
err51
errOAAI
errMueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen, V; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo, V; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; von Delft, Frank; Willson, Timothy M.; Winter, Georg E.; Workman, Paul; Arrowsmith, Cheryl H.
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Design, Synthesis, and Pharmacological Characterization of a Neutral, Non-Prodrug Thrombin Inhibitor with Good Oral Pharmacokinetics
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-10-27
err16
errOAAI
errHillisch, Alexander; Gericke, Kersten M.; Allerheiligen, Swen; Roehrig, Susanne; Schaefer, Martina; Tersteegen, Adrian; Schulz, Simone; Lienau, Philip; Gnoth, Mark; Puetter, Vera; Hillig, Roman C.; Heitmeier, Stefan
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err收藏
Druggability Assessment for Selected Serine Proteases in a Pharmaceutical Industry Setting
errCHEMMEDCHEM
IF3.4
err2020-09-21
err5
PREAI
errWehrhan, Leon; Hillisch, Alexander; Mundt, Stefan; Tersteegen, Adrian; Meier, Katharina
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Bayer's in silico ADMET platform: a journey of machine learning over the past two decades
errDRUG DISCOVERY TODAY
IF7.5
err2020-09-01
err108
errOAAI
errGoeller, Andreas H.; Kuhnke, Lara; Montanari, Floriane; Bonin, Anne; Schneckener, Sebastian; ter Laak, Antonius; Wichard, Joerg; Lobell, Mario; Hillisch, Alexander
err分享
err收藏
Structure-Permeability Relationship of Semipeptidic Macrocycles-Understanding and Optimizing Passive Permeability and Efflux Ratio
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-05-26
err24
PREAI
errLe Roux, Antoine; Blaise, Emilie; Boudreault, Pierre-Luc; Comeau, Christian; Doucet, Annie; Giarrusso, Marilena; Collin, Marie-Pierre; Neubauer, Thomas; Koelling, Florian; Goeller, Andreas H.; Seep, Lea; Tshitenge, Dieudonne T.; Wittwer, Matthias; Kullmann, Maximilian; Hillisch, Alexander; Mittendorf, Joachim; Marsault, Eric
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Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2019-11-01
err61
PREAI
errSchneckener, Sebastian; Grimbs, Sergio; Hey, Jessica; Menz, Stephan; Osmers, Maren; Schaper, Steffen; Hillisch, Alexander; Goeller, Andreas H.
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An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer - against all odds?
errDRUG DISCOVERY TODAY
IF7.5
err2019-03-01
err38
errOAAI
errFollmann, Markus; Briem, Hans; Steinmeyer, Andreas; Hillisch, Alexander; Schmitt, Monika H.; Haning, Helmut; Meier, Heinrich
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Reliable and Performant Identification of Low-Energy Conformers in the Gas Phase and Water
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2018-05-02
err25
PREAI
errCavasin, Anna Theresa; Hillisch, Alexander; Uellendahl, Felix; Schneckener, Sebastian; Goeller, Andreas H.
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Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence
errCHEMMEDCHEM
IF3.4
err2015-09-11
err58
PREAI
errHillisch, Alexander; Heinrich, Nikolaus; Wild, Hanno
err分享
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Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-09-01
err137
errOAAI
errAmazit, Larbi; Le Billan, Florian; Kolkhof, Peter; Lamribet, Khadija; Viengchareun, Say; Fay, Michel R.; Khan, Junaid A.; Hillisch, Alexander; Lombes, Marc; Rafestin-Oblin, Marie-Edith; Fagart, Jerome
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Best of Both Worlds: Combining Pharma Data and State of the Art Modeling Technology To Improve in Silico pKa Prediction两全其美: 结合制药数据和最先进的建模技术，以改善计算机pKa预测
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2014-12-16
err87
errOAAI
errFraczkiewicz, Robert; Lobell, Mario; Goeller, Andreas H.; Krenz, Ursula; Schoenneis, Rolf; Clark, Robert D.; Hillisch, Alexander
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Binding Free Energy Calculations for Lead Optimization: Assessment of Their Accuracy in an Industrial Drug Design Context
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2014-06-24
err150
PREAI
errHomeyer, Nadine; Stoll, Friederike; Hillisch, Alexander; Gohlke, Holger
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研究方向

暂时未获取到该数据
合作学者
合作期刊
Y
Yoshua Bengio
H 指数: 183 · 论文数: 1.3K
C
C.H. Arrowsmith
H 指数: 112 · 论文数: 3.1K
S
Stefan Knapp
H 指数: 111 · 论文数: 1.3K
T
Timothy M. Willson
H 指数: 110 · 论文数: 418
G
Giulio Superti‐Furga
H 指数: 100 · 论文数: 540
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