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边

边杉｜Shan Bian

tongji university
H指数:23
被引数:2,944
浏览量:0

个人简介

同济大学生命科学与技术学院研究员，同济大学附属东方医院再生医学研究所和心脏病全国重点实验室特聘研究员。结合临床队列分析、医学遗传学、人脑类器官和转基因动物模型，致力于环境和遗传因素导致出生缺陷尤其是神经发育障碍研究，以及人脑进化调控机制研究。研究成果以通讯作者（包括共同）身份发表在New England Journal of Medicine、Med、Journal of Clinical Investigation、EMBO Molecular Medicine、EMBO Reports、Journal of Genetics and Genomics等期刊。

教育背景

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工作经历

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荣誉奖项

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Anti-asthma drug montelukast induces autistic behaviors via disrupting neuronal retinoic acid signaling

抗哮喘药物孟鲁司特通过破坏神经元视黄酸信号诱导自闭症行为

Signal Transduction and Targeted Therapy
IF52.7
2026-06-020
OAAI
Zi-Jian Hao; Qiong-Hui Wu; Ya-Li Li; Zhen-Ming Guo; Zheng-Wei Li; Gui Wang; Meng Meng; Shi-Lin Yuan; Yilimire Wufuer; Meng-Huan Zhang; Jie Chen; Ting Yang; Meng-Xia Chen; Jiang Zhu; Wang Qi-Hang; Qiu Li; Shi-Hu Yu; Min Lu; Hai-Yi Xiong; Yu-Ru Feng; Meng-Qi Dong; Jun-Hao Xu; Jia-Lin Xu; Li Chen; Han-Ting Yang; Jing-Kun Miao; Hong Zhu; Bo Yang; Hui-Ying Zhao; Xiao-Ming Shi; Shan Bian; Ting-Yu Li; Rong-Gui Hu
Mutations in the spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly

SNW1剪接体基因的突变导致伴有小头畸形的神经发育障碍

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-09-160
OAAI
Ji, Lei; Yan, Jin; Losurdo, Nicole A.; Wang, Hua; Liu, Liangjie; Li, Keyi; Liu, Zhen; Guo, Zhenming; Xu, Jing; Bibo, Adriana; Ren, Decheng; Yang, Ke; Luo, Yingying; Yang, Fengping; Wang, Gui; Xiang, Zhenglong; Wang, Yuan; Zhan, Huaizhe; Pan, Hu; Hu, Juanli; Zhong, Jianmin; Abou Jamra, Rami; Zacher, Pia; Musante, Luciana; Faletra, Flavio; Costa, Paola; Zanus, Caterina; Couque, Nathalie; Ruaud, Lyse; Cueto-Gonzalez, Anna M.; Fernandez, Hector San Nicolas; Tizzano, Eduardo; Gil, Nuria Martinez; Liu, Xiaorong; Liao, Weiping; Farraj, Layal Abi; Huang, Alden Y.; Zhang, Liying; Murali, Aparna; Schmuel, Esther; Han, Christina S.; King, Kayla; Gu, Weiyue; Wang, Pengchao; Li, Kai; Link, Nichole; He, Guang; Bian, Shan; Biao, Xiao
Modeling disrupted synapse formation in wolfram syndrome using hESCs-derived neural cells and cerebral organoids identifies Riluzole as a therapeutic molecule
MOLECULAR PSYCHIATRY
IF10.1
2023-02-079
OAAI
Yuan, Fei; Li, Yana; Hu, Rui; Gong, Mengting; Chai, Mengyao; Ma, Xuefei; Cha, Jiaxue; Guo, Pan; Yang, Kaijiang; Li, Mushan; Xu, Minglu; Ma, Qing; Su, Qiang; Zhang, Chuan; Sheng, Zhejin; Wu, Heng; Wang, Yuan; Yuan, Wen; Bian, Shan; Shao, Li; Zhang, Ru; Li, Kaicheng; Shao, Zhen; Zhang, Zhen-Ning; Li, Weida
A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
EMBO MOLECULAR MEDICINE
IF8.3
2023-02-066
OAAI
Taubenschmid-Stowers, Jasmin; Orthofer, Michael; Laemmerer, Anna; Krauditsch, Christian; Rozsova, Marianna; Studer, Christian; Loetsch, Daniela; Gojo, Johannes; Gabler, Lisa; Dyczynski, Matheus; Efferth, Thomas; Hagelkruys, Astrid; Widhalm, Georg; Peyrl, Andreas; Spiegl-Kreinecker, Sabine; Hoepfner, Dominic; Bian, Shan; Berger, Walter; Knoblich, Juergen A.; Elling, Ulrich; Horn, Moritz; Penninger, Josef M.

研究方向

人脑发育与进化的机制研究鉴定神经发育障碍新致病遗传因素及其致病机制研究环境因素导致出生缺陷尤其是神经发育障碍的机制研究
郭贞明 封面图
郭贞明
H 指数:15论文数:62被引数:961
J
Juergen A. Knoblich
H 指数:84论文数:238被引数:3.8万
T
Tao Sun
H 指数:47论文数:170被引数:8,199
L
Li‐Pao Fang
H 指数:11论文数:25被引数:468
C
Christian Krauditsch
H 指数:6论文数:9被引数:614
A
Andrew Pollock
H 指数:21论文数:67被引数:1,992
Y
Yanxin Xu
H 指数:18论文数:66被引数:1,963
X
Xianshu Bai
H 指数:21论文数:47被引数:1,071
R
Renping Zhao
H 指数:24论文数:99被引数:2,091
N
Na Zhao
H 指数:13论文数:40被引数:667