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Y

Yanxin Xu

Massachusetts General Hospital
H指数:18
被引数:1,963

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OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

OGFOD1通过调控蛋白质合成使急性髓系白血病（AML）具有化疗和营养应激抗性。

Cell Metabolism
IF30.9
2025-09-160
PRE
Christina Mayerhofer; Dan Li; Trine Kristiansen; Ernst Mayerhofer; Azeem Sharda; Giulia Schiroli; Karin Gustafsson; Lingli He; Michael Mazzola; Sam Keyes; Anna Kiem; Eve Crompton; Yanxin Xu; Sovannarith Korm; Zhixun Dou; Charles Vidoudez; Peter G. Miller; Nick van Gastel; Timothy A. Graubert; David T. Scadden
WSTF nuclear autophagy regulates chronic but not acute inflammation

WSTF核自噬调节慢性而非急性炎症

Nature
IF48.5
2025-07-020
PRE
Yu Wang; Vinay V. Eapen; Yaosi Liang; Athanasios Kournoutis; Marc Samuel Sherman; Yanxin Xu; Angelique Onorati; Xianting Li; Xiaoting Zhou; Kathleen E. Corey; Kuo Du; Ana Maria Cabral Burkard; Chia-Kang Ho; Jing Xie; Hui Zhang; Raquel Maeso-Díaz; Xinyi Ma; Ulrike Rieprecht; Tara O’Brien; Murat Cetinbas; Lu Wang; Jihe Liu; Corey Bretz; Aaron P. Havas; Zhuo Zhou; Shannan J. Ho Sui; Srinivas Vinod Saladi; Ruslan I. Sadreyev; Peter D. Adams; Robert E. Kingston; Anna Mae Diehl; Benjamin Alman; Wolfram Goessling; Zhenyu Yue; Xiao-Fan Wang; Terje Johansen; Zhixun Dou
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

去抑制核内丙酮酸脱氢酶可诱导治疗性癌细胞重编程

Cell Metabolism
IF30.9
2025-06-110
PRE
Ting Zhao; Lingli He; Lai Ping Wong; Shenglin Mei; Jun Xia; Yanxin Xu; Jonathan G. Van Vranken; Michael Mazzola; Lei Chen; Catherine Rhee; Tiancheng Fang; Tsuyoshi Fukushima; Leanne C. Sayles; Matthew Diaz; J. Alex B. Gibbons; Raul Mostoslavsky; Steven P. Gygi; Zhixun Dou; David B. Sykes; Ruslan I. Sadreyev; E. Alejandro Sweet-Cordero; David T. Scadden
AML Stem Cell Clearance By Inhibiting Selenoprotein Biosynthesis That Causes Cgas-Sting Activation and Ferroptosis

通过抑制硒蛋白生物合成，引起Cgas-Sting激活和铁死亡，从而清除AML干细胞

BLOOD
IF23.1
2024-11-050
PRE
He, Lingli; Zhao, Ting; Leong, Wei Zhong; Sharda, Azeem; Mayerhofer, Christina; Mei, Shenglin; Bonilla, Gracia M.; Menendez-Gonzalez, Juan Bautista; Gustafsson, Karin; Fukushima, Tsuyoshi; Kristiansen, Trine A.; Lee, Ji-Won; Xu, Yanxin; Budnik, Bogdan; Sadreyev, Ruslan; Dou, Zhixun; Sykes, David B.; Scadden, David
Modulating mRNA Translation Fidelity As a Novel Mechanism for AML Chemoresistance

调节mRNA翻译保真度作为一种AML化疗耐药的新机制

BLOOD
IF23.1
2024-11-050
PRE
Mayerhofer, Christina; Li, Dan; Kristiansen, Trine A.; Mayerhofer, Ernst; Sharda, Azeem; He, Lingli; Mazzola, Michael; Schiroli, Giulia; Gustafsson, Karin; Keyes, Sam; Kiem, Anna; Crompton, Eve; Xu, Yanxin; Dou, Zhixun; Vidoudez, Charles; Miller, Peter G.; Van Gastel, Nick; Scadden, David

研究方向

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康九红 封面图
康九红
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郭旭东 封面图
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Y
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H 指数:12论文数:35被引数:502
Z
Zhixun Dou
H 指数:31论文数:72被引数:7,291
D
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H 指数:124论文数:667被引数:6.7万
L
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Yaxin Guo
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J
Jiajie Xi
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边
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Z
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