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J

James E. McLaren

Cardiff University
H指数:33
被引数:4,822

个人简介

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教育背景

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工作经历

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荣誉奖项

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Cytomegalovirus-induced T cell responses accelerate Alzheimer’s disease progression in mice

巨细胞病毒诱导的T细胞反应加速小鼠阿尔茨海默病进展

Brain
IF11.7
2026-07-130
OAAI
Morgan Marsden; James E McLaren; Ryan J Bevan; Daisy Penn-Ripley; Michelle Somerville; Sarah N Lauder; Manon H Jones; Lila-Blythe Maros; Matthew R McGurk; Awen Gallimore; David A Price; Kelly L Miners; Kristin Ladell; Florian A Siebzehnrubl; Timothy R Hughes; Ian R Humphreys; Mathew Clement; null
A rapid time-resolved host gene expression signature predicts responses to antibiotic treatment in neonatal bacterial sepsis

快速时间分辨宿主基因表达谱可预测新生儿细菌性脓毒症对抗生素治疗的反应

Science Translational Medicine
IF14.6
2025-11-260
PRE
Edward C. Parkinson; W. John Watkins; Sarah Edkins; James E. McLaren; Michelle N. Clements; Robert Andrews; Federico Liberatore; Irja Lutsar; Mark A. Turner; Emmanuel Roilides; Paul T. Heath; Michael Sharland; Louise F. Hill; Peter Ghazal;
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2

大流行时代的VDJdb: SARS-CoV-2特异性T细胞受体纲要

NATURE METHODS
IF32.1
2022-08-1568
OA
Goncharov, Mikhail; Bagaev, Dmitry; Shcherbinin, Dmitrii; Zvyagin, Ivan; Bolotin, Dmitry; Thomas, Paul G.; Minervina, Anastasia A.; Pogorelyy, Mikhail V.; Ladell, Kristin; McLaren, James E.; Price, David A.; Nguyen, Thi H. O.; Rowntree, Louise C.; Clemens, E. Bridie; Kedzierska, Katherine; Dolton, Garry; Rius, Cristina Rafael; Sewell, Andrew; Samir, Jerome; Luciani, Fabio; Zornikova, Ksenia V.; Khmelevskaya, Alexandra A.; Sheetikov, Saveliy A.; Efimov, Grigory A.; Chudakov, Dmitry; Shugay, Mikhail
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation

细菌炎症期间氧脂素代谢受线粒体 β-氧化控制

NATURE COMMUNICATIONS
IF15.7
2022-01-1038
OAAI
Misheva, Mariya; Kotzamanis, Konstantinos; Davies, Luke C.; Tyrrell, Victoria J.; Rodrigues, Patricia R. S.; Benavides, Gloria A.; Hinz, Christine; Murphy, Robert C.; Kennedy, Paul; Taylor, Philip R.; Rosas, Marcela; Jones, Simon A.; McLaren, James E.; Deshpande, Sumukh; Andrews, Robert; Schebb, Nils Helge; Czubala, Magdalena A.; Gurney, Mark; Aldrovandi, Maceler; Meckelmann, Sven W.; Ghazal, Peter; Darley-Usmar, Victor; White, Daniel A.; O'Donnell, Valerie B.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-07-167
OAAI
Clement, Mathew; Knezevic, Lea; Dockree, Tamsin; McLaren, James E.; Ladell, Kristin; Miners, Kelly L.; Llewellyn-Lacey, Sian; Rubina, Anzelika; Francis, Ore; Cole, David K.; Sewell, Andrew K.; Bridgeman, John S.; Price, David A.; van den Berg, Hugo A.; Wooldridge, Linda
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans

小鼠和人类的促炎T细胞群共表达 α β 和 γ δ T细胞受体

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2020-02-2730
OAAI
Edwards, Sarah C.; Sutton, Caroline E.; Ladell, Kristin; Grant, Emma J.; McLaren, James E.; Roche, Fiona; Dash, Pradyot; Apiwattanakul, Nopporn; Awad, Walid; Miners, Kelly L.; Lalor, Stephen J.; Ribot, Julie C.; Baik, Song; Moran, Barry; McGinley, Aoife; Pivorunas, Valerie; Dowding, Lori; Macoritto, Michael; Paez-Cortez, Jesus; Slavin, Anthony; Anderson, Graham; Silva-Santos, Bruno; Hokamp, Karsten; Price, David A.; Thomas, Paul G.; McLoughlin, Rachel M.; Mills, Kingston H. G.
CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells

人扁桃体和血液中的CD4 T滤泡辅助细胞是克隆会聚的，但与非Tfh CD4细胞不同。

CELL REPORTS
IF6.9
2020-01-0174
OAAI
Brenna, Elena; Davydov, Alexey N.; Ladell, Kristin; McLaren, James E.; Bonaiuti, Paolo; Metsger, Maria; Ramsden, James D.; Gilbert, Sarah C.; Lambe, Teresa; Price, David A.; Campion, Suzanne L.; Chudakov, Dmitriy M.; Borrow, Persephone; McMichael, Andrew J.
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis
COMMUNICATIONS BIOLOGY
IF5.1
2019-06-0555
OAAI
Wong, Emily B.; Gold, Marielle C.; Meermeier, Erin W.; Xulu, Bongiwe Z.; Khuzwayo, Sharon; Sullivan, Zuri A.; Mahyari, Eisa; Rogers, Zoe; Kloverpris, Henrik; Sharma, Prabhat K.; Worley, Aneta H.; Lalloo, Umesh; Baijnath, Prinita; Ambaram, Anish; Naidoo, Leon; Suleman, Moosa; Madansein, Rajhmun; McLaren, James E.; Ladell, Kristin; Miners, Kelly L.; Price, David A.; Behar, Samuel M.; Nielsen, Morten; Kasprowicz, Victoria O.; Leslie, Alasdair; Bishai, William R.; Ndung'u, Thumbi; Lewinsohn, David M.
Memory CD4+ T cells are generated in the human fetal intestine
NATURE IMMUNOLOGY
IF27.6
2019-01-21115
OAAI
Li, Na; van Unen, Vincent; Abdelaal, Tamim; Guo, Nannan; Kasatskaya, Sofya A.; Ladell, Kristin; McLaren, James E.; Egorov, Evgeny S.; Izraelson, Mark; Lopes, Susana M. Chuva de Sousa; Hollt, Thomas; Britanova, Olga V.; Eggermont, Jeroen; de Miranda, Noel F. C. C.; Chudakov, Dmitriy M.; Price, David A.; Lelieveldt, Boudewijn P. F.; Koning, Frits

研究方向

暂未获取到该数据
D
David A. Price
H 指数:116论文数:880被引数:6.0万
K
Kristin Ladell
H 指数:47论文数:203被引数:8,237
K
Kelly L. Miners
H 指数:24论文数:77被引数:1,634
M
Mathew Clement
H 指数:29论文数:64被引数:2,463
E
Emma Gostick
H 指数:64论文数:174被引数:1.5万
S
Sian Llewellyn‐Lacey
H 指数:27论文数:66被引数:5,621
L
Linda Wooldridge
H 指数:36论文数:127被引数:5,685
J
Jamie Rossjohn
H 指数:118论文数:991被引数:4.8万
A
Andrew K. Sewell
H 指数:70论文数:338被引数:1.7万
D
Dipak P. Ramji
H 指数:39论文数:142被引数:7,206