Andrew K. Sewell - Publications, H-index & Citations

Andrew K. Sewell

kumamoto university

70H指数

338论文数

1.7W被引数

收录论文 145

发表时间

VDJdb in 2026: boosting T-cell receptor recognition evidence using paratope embeddings and AI-based structure prediction VDJdb在2026年：利用表位嵌入和基于AI的结构预测增强T细胞受体识别证据

Nucleic Acids Research

IF13.1

2026-09-23

OAAI

Daniil V Luppov; Anna E Koneva; Dmitry V Bagaev; Anastasiia V Alexandrova; Elizaveta K Vlasova; Dmitry M Chudakov; Chihiro Motozono; Andrew K Sewell; Mikhail Shugay; null

Optimized procurement of cancer-reactive T-cell receptors from clinical samples 从临床样本中优化获取肿瘤反应性T细胞受体

Immunotherapy Advances

IF4.9

2026-06-22

OAAI

Marine E Caillaud; Cristina Rius; Théo Morin; Li Rong Tan; Hannah L Thomas; Amber Rogers; Joshua Hick; Morten Nielsen; Md Samiul Hasan; Inge Marie Svane; Barbara Szomolay; Andrew K Sewell; Garry Dolton; null

Position-5-driven reorientation of an immunodominant HLA-A*24:02 SARS-CoV-2 epitope drives universal T cell escape 位置5驱动的免疫优势HLA-A*24:02 SARS-CoV-2表位重取向驱动通用T细胞逃逸

JCI Insight

IF6.1

2026-05-08

OAAI

Nakama, Takeshi; Wall, Aaron; Dolton, Garry; Tan, Li Rong; Thomas, Hannah; Hamana, Hiroshi; Aritsu, Yoshiki; Tan, Toong Seng; Toyoda, Mako; Goto, Yoshihiko; Li, Huanyu; Kitamatsu, Mizuki; Udaka, Keiko; Miyashita, Yusuke; Oshiumi, Hiroyuki; Nakamura, Kimitoshi; Nagasaki, Yoji; Minami, Rumi; Nakata, Hirotomo; Rizkallah, Pierre J.; Kishi, Hiroyuki; Ueno, Takamasa; Sewell, Andrew K.; Motozono, Chihiro

A probiotic bacterium modulates antitumour γδ T-cell responses in lung cancer 一种益生菌细菌调节肺癌中抗肿瘤γδ T细胞反应

Frontiers in Immunology

IF5.9

2026-03-26

OAAI

YG Yoshihiko Goto †; GD Garry Dolton †; HT Hannah Thomas; TM Théo Morin; YT Yuka Tajima; KI Kosuke Imamura; SS Shinya Sakata; KO Kentaro Oka; AH Atsushi Hayashi; MT Motomichi Takahashi; TU Takamasa Ueno; TS Takuro Sakagami; YT Yusuke Tomita; AK Andrew K. Sewell ‡; CM Chihiro Motozono ‡

MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens MR1配体交联鉴定出维生素B6代谢物为TCR反应性抗原

Cell Reports Methods

IF4.5

2025-08-04

OAAI

Thierry Schmidlin; Enas Behiry; Hannah Thomas; Garry Dolton; Fabio Marino; Samiul Hasan; Magdalena von Essen; Rose M. Gathungu; Barbara A. Steigenberger; Hayden Selvadurai; Joseph Dukes; Paul E. Brennan; Owen B. Spiller; Jonathan D. Silk; Andrew K. Sewell; Nicola Ternette

HLA A*24:02-restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-09-17

OAAI

Dolton, Garry; Bulek, Anna; Wall, Aaron; Thomas, Hannah; Hopkins, Jade R.; Rius, Cristina; Galloway, Sarah A. E.; Whalley, Thomas; Tan, Li Rong; Morin, Theo; Omidvar, Nader; Fuller, Anna; Topley, Katie; Hasan, Md Samiul; Jain, Shikha; D'Souza, Nirupa; Hodges-Hoyland, Thomas; Spiller, Owen B.; Kronenberg-Versteeg, Deborah; Szomolay, Barbara; van den Berg, Hugo A.; Jones, Lucy C.; Peakman, Mark; Cole, David K.; Rizkallah, Pierre J.; Sewell, Andrew K.

Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies T细胞恶性肿瘤中靶向TRBC1和TRBC2的免疫疗法的结构指导工程

NATURE COMMUNICATIONS

IF15.7

2024-02-21

OAAI

Ferrari, Mathieu; Righi, Matteo; Baldan, Vania; Wawrzyniecka, Patrycja; Bulek, Anna; Kinna, Alexander; Ma, Biao; Bughda, Reyisa; Akbar, Zulaikha; Srivastava, Saket; Gannon, Isaac; Robson, Mathew; Sillibourne, James; Jha, Ram; El-Kholy, Mohamed; Amin, Oliver Muhammad; Kokalaki, Evangelia; Banani, Mohammed Amin; Hussain, Rehan; Day, William; Lim, Wen Chean; Ghongane, Priyanka; Hopkins, Jade R.; Jungherz, Dennis; Herling, Marco; Welin, Martin; Surade, Sachin; Dyson, Michael; Mccafferty, John; Logan, Derek; Cordoba, Shaun; Thomas, Simon; Sewell, Andrew; Maciocia, Paul; Onuoha, Shimobi; Pule, Martin

Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+T cell immunity

CELL REPORTS

IF6.9

2023-08-01

OAAI

Chen, Yuan; Mason, Georgina H.; Scourfield, D. Oliver; Greenshields-Watson, Alexander; Haigh, Tracey A.; Sewell, Andrew K.; Long, Heather M.; Gallimore, Awen M.; Rizkallah, Pierre; MacLachlan, Bruce J.; Godkin, Andrew

VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2 大流行时代的VDJdb: SARS-CoV-2特异性T细胞受体纲要

NATURE METHODS

IF32.1

2022-08-15

OAAI

Goncharov, Mikhail; Bagaev, Dmitry; Shcherbinin, Dmitrii; Zvyagin, Ivan; Bolotin, Dmitry; Thomas, Paul G.; Minervina, Anastasia A.; Pogorelyy, Mikhail V.; Ladell, Kristin; McLaren, James E.; Price, David A.; Nguyen, Thi H. O.; Rowntree, Louise C.; Clemens, E. Bridie; Kedzierska, Katherine; Dolton, Garry; Rius, Cristina Rafael; Sewell, Andrew; Samir, Jerome; Luciani, Fabio; Zornikova, Ksenia V.; Khmelevskaya, Alexandra A.; Sheetikov, Saveliy A.; Efimov, Grigory A.; Chudakov, Dmitry; Shugay, Mikhail

Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells

MUCOSAL IMMUNOLOGY

IF7.6

2022-03-01

OAAI

Martini, Veronica; Edmans, Matthew; Gubbins, Simon; Jayaraman, Siddharth; Paudyal, Basudev; Morgan, Sophie; McNee, Adam; Morin, Theo; Rijal, Pramila; Gerner, Wilhelm; Sewell, Andrew K.; Inoue, Ryo; Bailey, Mick; Connelley, Timothy; Charleston, Bryan; Townsend, Alain; Beverley, Peter; Tchilian, Elma

CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-07-16

OAAI

Clement, Mathew; Knezevic, Lea; Dockree, Tamsin; McLaren, James E.; Ladell, Kristin; Miners, Kelly L.; Llewellyn-Lacey, Sian; Rubina, Anzelika; Francis, Ore; Cole, David K.; Sewell, Andrew K.; Bridgeman, John S.; Price, David A.; van den Berg, Hugo A.; Wooldridge, Linda

Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs (vol 206, pg 652, 2021)

JOURNAL OF IMMUNOLOGY

IF3.4

2021-07-01

OAAI

Martini, Veronica; Paudyal, Basu; Chrun, Tiphany; McNee, Adam; Edmans, Matthew; Maze, Emmanuel Atangana; Clark, Beckie; Nunez, Alejandro; Dolton, Garry; Sewell, Andrew; Beverley, Peter; MacLoughlin, Ronan; Townsend, Alain; Tchilian, Elma

The burgeoning role of MR1-restricted T-cells in infection, cancer and autoimmune disease

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2021-04-01

OAAI

Crowther, Michael D.; Sewell, Andrew K.

Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-02-02

OAAI

Edmans, Matthew; McNee, Adam; Porter, Emily; Vatzia, Eleni; Paudyal, Basu; Martini, Veronica; Gubbins, Simon; Francis, Ore; Harley, Ross; Thomas, Amy; Burt, Rachel; Morgan, Sophie; Fuller, Anna; Sewell, Andrew; Charleston, Bryan; Bailey, Mick; Tchilian, Elma

Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life (vol 11, 1587, 2020)

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-12-21

OAAI

Attaf, Meriem; Roider, Julia; Malik, Amna; Rafael, Cristina Rius; Dolton, Garry; Prendergast, Andrew J.; Leslie, Alasdair; Ndung'u, Thumbi; Kloverpris, Henrik N.; Sewell, Andrew K.; Goulder, Philip J.

Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life 生命早期存在巨细胞病毒介导的T细胞受体库扰动

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-09-30

OAAI

Attaf, Meriem; Roider, Julia; Malik, Amna; Rius Rafael, Cristina; Dolton, Garry; Predergast, Andrew J.; Leslie, Alasdair; Ndung'u, Thumbi; Kloverpris, Henrik N.; Sewell, Andrew K.; Goulder, Philip J.

Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy

MOLECULAR THERAPY-ONCOLYTICS

IF0

2020-09-01

OAAI

Crean, Rory M.; MacLachlan, Bruce J.; Madura, Florian; Whalley, Thomas; Rizkallah, Pierre J.; Holland, Christopher J.; McMurran, Catriona; Harper, Stephen; Godkin, Andrew; Sewell, Andrew K.; Pudney, Christopher R.; van der Kamp, Marc W.; Cole, David K.

CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features

CELL REPORTS

IF6.9

2020-07-01

OAAI

Greenshields-Watson, Alexander; Attaf, Meriem; MacLachlan, Bruce J.; Whalley, Thomas; Rius, Cristina; Wall, Aaron; Lloyd, Angharad; Hughes, Hywel; Strange, Kathryn E.; Mason, Georgina H.; Schauenburg, Andrea J.; Hulin-Curtis, Sarah L.; Geary, James; Chen, Yuan; Lauder, Sarah N.; Smart, Kathryn; Vijaykrishna, Dhanasekaran; Grau, Miguel L.; Shugay, Mikhail; Andrews, Robert; Dolton, Garry; Rizkallah, Pierre J.; Gallimore, Awen M.; Sewell, Andrew K.; Godkin, Andrew J.; Cole, David K.

Synthesis and Biological Evaluation of Hapten-Clicked Analogues of The Antigenic Peptide Melan-A/MART-126(27L)-35

CHEMMEDCHEM

IF3.4

2020-04-06

OAAI

Tarbe, Marion; Miles, John J.; Edwards, Emily S. J.; Miles, Kim M.; Sewell, Andrew K.; Baker, Brian M.; Quideau, Stephane

Peptide cargo tunes a network of correlated motions in human leucocyte antigens

FEBS JOURNAL

IF4.2

2020-03-26

OAAI

Hopkins, Jade R.; Crean, Rory M.; Catici, Dragana A. M.; Sewell, Andrew K.; Arcus, Vickery L.; van der Kamp, Marc W.; Cole, David K.; Pudney, Christopher R.

研究方向