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J

Jack Uetrecht

University of Toronto

62H指数
262论文数
1.2W被引数
收录论文 78
发表时间
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Hepatic responses as potential biomarkers of idiosyncratic drug reaction risk肝脏反应作为特异质药物反应风险的潜在生物标志物
errToxicological Sciences
IF4.1
err2026-07-29
err0
errOAAI
errJiamin Liao; Xiaotian Lyu; Kristy Yang; Lucia Chen; Jack Uetrecht
err分享
err收藏
DILI prediction in drug development: present and future药物开发中的DILI预测：现状与未来
errEXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
IF3.4
err2025-04-20
err0
PREAI
errUetrecht, Jack
err分享
err收藏
TAK-994 mechanistic investigation into drug-induced liver injury药物性肝损伤的TAK-994机制研究
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-01-09
err1
PREAI
errShinozawa, Tadahiro; Miyamoto, Kazumasa; Baker, Kevin S.; Faber, Samantha C.; Flores, Ramon; Uetrecht, Jack; von Hehn, Christian; Yukawa, Tomoya; Tohyama, Kimio; Kadali, Harisha; von Grotthuss, Marcin; Sudo, Yusuke; Smith, Erin N.; Diogo, Dorothee; Zhu, Andy Z. X.; Dragan, Yvonne; Cebers, Gvido; Wagoner, Matthew P.
err分享
err收藏
Evaluation of the biodistribution and preliminary safety profile of a novel brain-targeted manganese dioxide-based nanotheranostic system for Alzheimer's disease
errNANOTOXICOLOGY
IF3.4
err2024-06-07
err0
PREAI
errLi, Lily Yi; Park, Elliya; He, Chunsheng; Abbasi, Azhar Z.; Henderson, Jeffrey T.; Fraser, Paul E.; Uetrecht, Jack P.; Rauth, Andrew M.; Wu, Xiao Yu
err分享
err收藏
The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine
errTOXICOLOGICAL SCIENCES
IF4.1
err2024-05-15
err1
PREAI
errCho, Tiffany; Hayes, Anthony; Henderson, Jeffrey T.; Uetrecht, Jack
err分享
err收藏
The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury
errTOXICOLOGICAL SCIENCES
IF4.1
err2024-04-18
err1
PREAI
errJee, Alison; Sernoskie, Samantha Christine; Uetrecht, Jack
err分享
err收藏
Involvement of Extracellular Vesicles in the Proinflammatory Response to Clozapine: Implications for Clozapine-Induced Agranulocytosis
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2024-03-01
err1
errOAAI
errSernoskie, Samantha Christine; Bonneil, Eric; Thibault, Pierre; Jee, Alison; Uetrecht, Jack
err分享
err收藏
The development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions
errTOXICOLOGICAL SCIENCES
IF4.1
err2024-01-16
err2
PREAI
errCho, Tiffany; Wierk, Antonia; Gertsenstein, Marina; Rodgers, Christopher E.; Uetrecht, Jack; Henderson, Jeffrey T.
err分享
err收藏
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2023-11-03
err5
errOAAI
errCao, Yanshan; Bairam, Ahsan; Liu, Ming-Cheh; Uetrecht, Jack
err分享
err收藏
Sulfation of 12-hydroxy-nevirapine by human SULTs and the effects of genetic polymorphisms of SULT1A1 and SULT2A1
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2022-10-01
err1
PREAI
errKurogi, Katsuhisa; Cao, Yanshan; Segawa, Koshi; Sakakibara, Yoichi; Suiko, Masahito; Uetrecht, Jack; Liu, Ming-Cheh
err分享
err收藏
Idiosyncratic Drug Reactions: A 35-Year Chemical Research in Toxicology Perspective
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2022-06-10
err12
errOAAI
errUetrecht, Jack
err分享
err收藏
Clozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis
errTOXICOLOGICAL SCIENCES
IF4.1
err2021-12-22
err29
errOAAI
errSernoskie, Samantha Christine; Lobach, Alexandra R.; Kato, Ryuji; Jee, Alison; Weston, Joseph Kyle; Uetrecht, Jack
err分享
err收藏
The Emerging Role of the Innate Immune Response in Idiosyncratic Drug Reactions
errPHARMACOLOGICAL REVIEWS
IF17.3
err2021-07-01
err24
errOAAI
errSernoskie, Samantha Christine; Jee, Alison; Uetrecht, Jack Paul
err分享
err收藏
Liver Injury Caused by Green Tea Extract in PD-1-/- Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2021-02-22
err20
PREAI
errCho, Tiffany; Wang, Xijin; Yeung, Karen; Cao, Yanshan; Uetrecht, Jack
err分享
err收藏
Testing Possible Risk Factors for Idiosyncratic Drug-Induced Liver Injury Using an Amodiaquine Mouse Model and Co-treatment with 1-Methyl-D-Tryptophan or Acetaminophen使用阿莫地喹小鼠模型和1-甲基-d-色氨酸或对乙酰氨基酚共同治疗测试特异质药物引起的肝损伤的可能危险因素
errACS OMEGA
IF4.3
err2021-02-07
err5
errOAAI
errCho, Tiffany; Kok, Lie Yun; Uetrecht, Jack
err分享
err收藏
Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury
errTOXICOLOGICAL SCIENCES
IF4.1
err2021-01-04
err7
errOAAI
errCao, Yanshan; Bairam, Ahsan; Jee, Alison; Liu, Ming; Uetrecht, Jack
err分享
err收藏
Best practices for detection, assessment and management of suspected immune-mediated liver injury caused by immune checkpoint inhibitors during drug development
errJOURNAL OF AUTOIMMUNITY
IF7
err2020-11-01
err38
errOAAI
errRegev, Arie; Avigan, Mark, I; Kiazand, Alexandre; Vierling, John M.; Lewis, James H.; Omokaro, Stephanie O.; Di Bisceglie, Adrian M.; Fontana, Robert J.; Bonkovsky, Herbert L.; Freston, James W.; Uetrecht, Jack P.; Miller, Ethan D.; Pehlivanov, Nonko D.; Haque, Syed Asif; Harrison, Melanie J.; Kullak-Ublick, Gerd A.; Li, Hewei; Patel, Niti N.; Patwardhan, Meenal; Price, Karen D.; Watkins, Paul B.; Chalasani, Naga P.
err分享
err收藏
Response to the Letter to the Editor Concerning the Article Rotenone Increases Isoniazid Toxicity but Does Not Cause Liver Injury: Implications for the Hypothesis That Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury by Bernard Fromenty
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2019-12-10
err1
errOAAI
errCho, Tiffany; Uetrecht, Jack
err分享
err收藏
Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2019-06-19
err13
PREAI
errCho, Tiffany; Wang, Xijin; Uetrecht, Jack
err分享
err收藏
The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2018-06-25
err3
PREAI
errMak, Alastair; Cho, Tiffany Elizabeth; Uetrecht, Jack
err分享
err收藏

研究方向

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