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R

Rosalie C. Sears

oregon health & science university

59H指数
526论文数
1.5W被引数
收录论文 149
发表时间
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Schedule-dependent efficacy of gemcitabine and RAS(ON) inhibition in orthotopic pancreatic cancer: implications for clinical trial design吉西他滨和RAS(ON)抑制的时序依赖性疗效：对临床试验设计的启示
errCancer Letters
IF10.1
err2026-09-30
err0
PREAI
errKyle P. Gribbin; Hen Halamish; Ivan Rodriguez Siordia; Jennifer M. Finan; Michael J. Pishvaian; Charles D. Lopez; Adel Kardosh; Shaun Goodyear; Rosalie C. Sears; Teresa Zimmers; Aaron Grossberg; Katelyn T. Byrne; Jonathan R. Brody
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err收藏
The PancreaSure Multianalyte Blood Test Performs Well at Distinguishing Early-Stage Pancreatic Ductal Adenocarcinoma from High-Risk Controls: A Retrospective Secondary AnalysisPancreaSure多分析物血液检测在区分早期胰腺导管腺癌与高危对照组方面表现良好：一项回顾性二次分析
errJournal of Clinical Medicine
IF2.9
err2026-09-23
err0
errOAAI
errTamas Gonda; Salvatore Paiella; Rosalie C. Sears; Erkut Borazanci; Patricio M. Polanco; Sonia S. Kupfer; Fay Kastrinos; Walter G. Park; Kelly Hedger; Lisa Ford; Thomas King; Norma A. Palma; Randall E. Brand
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GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombinationGNL3泛素化对于同源重组修复DNA双链断裂至关重要
errNature Communications
IF15.7
err2026-08-24
err0
errOAAI
errYunhan Yang; Yanping Li; Roselyn S. Dai; Canping Chen; Keith Zientek; Ashok P. Reddy; Zheng Xia; Rosalie C. Sears; Xiao-Xin Sun; Mu-Shui Dai
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Liquid Biopsy Differentiation of Pancreatic Cancer From Non-Cancerous Pancreatic Disease Using Dielectrophoresis-Recovered Nanoparticles Carrying Cell-Free DNA and Protein Biomarkers利用介电泳回收的携带游离DNA和蛋白质生物标志物的纳米颗粒，通过液体活检区分胰腺癌与非癌性胰腺疾病
errSmall
IF12.1
err2026-04-08
err0
errOAAI
errAnna Malakian; Augusta Modestino; Jesus Bueno; Archana Machireddy; Jason Ware; Sean Hamilton; Ella Stimson; Sarah Mitchell; Joshua C. Saldivar; Ashley R. Woodfin; Corey M. Dambacher; Kyle Gustafson; Delaney Shea; Srivathsan Ranganathan; Mehrzad Sasanpour; Christian Ross; Dove Keith; Jeong Youn Lim; Xubo Song; Scott M. Lippman; Rosalie Sears; Terry Morgan; Michael Heller; Stuart D. Ibsen
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MicroCT Enables Simultaneous Longitudinal Tracking of Murine Pancreatic Cancer Progression and CachexiaMicroCT实现了对小鼠胰腺癌进展和恶病质的同步纵向跟踪
errCancer Research Communications
IF0
err2025-12-01
err0
errOAAI
errPelz, Katherine R.; Jimenez, Philip; Daniel, Colin J.; Newton, Samuel D.; Cunningham, Melissa; Sears, Rosalie C.; Worth, Patrick J.; Brody, Jonathan R.; Zimmers, Teresa A.
err分享
err收藏
Validation of a Serum-Based Biomarker Signature for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma血清基生物标志物特征在早期胰腺导管腺癌检测中的验证
errGastroenterology
IF25.1
err2025-10-27
err0
errOAAI
errAimee L. Lucas; Diane M. Simeone; Bryson W. Katona; Salvatore Paiella; George Zogopoulos; Rosalie C. Sears; Eli M. Grindedal; Raymond C. Wadlow; Erkut Borazanci; Ora K. Gordon; Fay Kastrinos; Jose G. Trevino; Sonia S. Kupfer; Walter G. Park; Jessica N. Everett; Natasha M. Kureshi; George DeMuth; Lisa Ford; Thomas King; Norma A. Palma; Randall E. Brand
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err收藏
High Performance of a Blood-Based Biomarker Test to Detect Early-Stage Pancreatic Cancer in a High-Risk Population, Across 2 Independent Clinical Validation Studies一项血液生物标志物检测在两项独立临床验证研究中，对高风险人群中早期胰腺癌的高性能检测。
errAMERICAN JOURNAL OF GASTROENTEROLOGY
IF7.6
err2025-10-01
err0
PREAI
errPolanco, Patricio M.; Lucas, Aimee; Brand, Randall; Gonda, Tamas; Borazanci, Erkut; Trevino, Jose; Glazer, Evan; Paiella, Salvatore; Sears, Rosalie; Grindedal, Eli M.; Wadlow, Raymond; Katona, Bryson W.; Zogopoulos, George; Sussman, Daniel A.; Gordon, Ora K.; King, Thomas; Dumuth, George; Ford, Lisa; Palma, Norma A.
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Nuclear cGAS mediated Replication Stress and Mitotic Catastrophe can Overcome Gemcitabine Resistance核cGAS介导的复制应激和有丝分裂灾难可以克服吉西他滨耐药性
errCancer Letters
IF10.1
err2025-09-03
err0
PREAI
errSoon Young Park; Kang Jin Jeong; Alfonso Poire; Bo Young Jeong; Yuhan Sheng; Tugba Y. Ozmen; Matthew J. Rames; Isabel A. English; Jonathan R. Brody; Rosalie C. Sears; Gordon B. Mills
err分享
err收藏
Protein phosphatase 2A as a therapeutic target in pancreatic cancer: past insights, recent advances, and future directions蛋白磷酸酶2A作为胰腺癌的治疗靶点：既往见解、近期进展及未来方向
errCURRENT OPINION IN PHYSIOLOGY
IF0
err2025-09-01
err0
PREAI
errShah, Vidhi M.; Sears, Rosalie C.
err分享
err收藏
Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients胰腺癌的无细胞RNA检测：用于诊断前高风险和有症状患者
errNature Communications
IF15.7
err2025-08-09
err0
errOAAI
errTravis W. Moore; Elias Spiliotopoulos; Rowan L. Callahan; C. Ward Kirschbaum; Conner F. Bailey; Hyun Ji Kim; Breeshey Roskams-Hieter; Florian Goncalves; Dove Keith; Aaron J. Grossberg; Paul T. Spellman; Gordon B. Mills; Rosalie C. Sears; Terry K. Morgan; Thuy T. M. Ngo
err分享
err收藏
OmicsTweezer: A distribution-independent cell deconvolution model for multi-omics DataOmicsTweezer：一种分布无关的多组学数据细胞分解模型
errCell Genomics
IF9
err2025-07-16
err0
errOAAI
errXinxing Yang; Faming Zhao; Tao Ren; Canping Chen; Katelyn T. Byrne; Alexey V. Danilov; Rosalie C. Sears; Peter S. Nelson; Lisa M. Coussens; Gordon B. Mills; Zheng Xia
err分享
err收藏
Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer自扩增NRF2-EZH2表观遗传环将KRAS启动的祖细胞转化为侵袭性胰腺癌
errNature Cancer
IF28.5
err2025-06-30
err0
PREAI
errLaura Antonucci; Na Li; Angeles Duran; Isidoro Cobo; Chiara Nicoletti; Kosuke Watari; Shuvro Prokash Nandi; Feng Zhu; Yongmei Zhao; Irene Riahi; Motoyuki Tsuda; Vidhi M. Shah; Terry Morgan; Trent Waugh; Luca Caputo; Yuan Liu; Alexandra Rundberg Nilsson; Hongxu Xian; Jelena Todoric; Li Gu; Elsa Sanchez-Lopez; Guido Eibl; Emily A. Vucic; Michal Krawczyk; Qianlan Xu; Andrew M. Lowy; Georgia Hatzivassiliou; Merone Roose-Girma; Dorota Skowronska-Krawczyk; David A. Scott; Dafna Bar-Sagi; Pablo Tamayo; Ying Wu; Rosalie C. Sears; Christopher K. Glass; Ludmil B. Alexandrov; Pier Lorenzo Puri; David W. Dawson; Yinling Hu; Maria T. Diaz-Meco; Jorge Moscat; Michael Karin
err分享
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HMG Box-containing Protein 1 (HBP1) Protects Against Pancreatic Injury in Acute Pancreatitis but Promotes Neoplastic ProgressionHMG Box-containing Protein 1 (HBP1) 在急性胰腺炎中保护胰腺免受损伤，但促进肿瘤进展。
errCellular and Molecular Gastroenterology and Hepatology
IF7.4
err2025-05-20
err0
errOAAI
errSeung-Won Lee; Taelor Ekstrom; Elise C. Manalo; Shangyuan Ye; Mark Berry; Dmytro Grygoryev; Malwina Szczepaniak; Jinho Lee; Carlos Origel Marmolejo; Syber Haverlack; Juyoung Lee; Vidhi M. Shah; Dove Keith; John L. Muschler; Koei Chin; Rosalie C. Sears; Stuart P. Weisberg; Terry Morgan; Jungsun Kim
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err收藏
Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanomaα-突触核蛋白调控黑素瘤中核仁DNA双链断裂修复
errSCIENCE ADVANCES
IF12.5
err2025-04-11
err0
errOAAI
errArnold, Moriah R.; Cohn, Gabriel M.; Oxe, Kezia Catharina; Elliott, Somarr N.; Moore, Cynthia; Zhou, Allison May; Laraia, Peter V.; Shekoohi, Sahar; Brownell, Dillon; Sears, Rosalie C.; Woltjer, Randall L.; Meshul, Charles K.; Witt, Stephan N.; Larsen, Dorthe H.; Unni, Vivek K.
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Early detection of pancreatic cancer by a high-throughput protease-activated nanosensor assay通过高通量蛋白酶激活纳米传感器检测早期胰腺癌
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-02-12
err3
PREAI
errMontoya Mira, Jose L.; Quentel, Arnaud; Patel, Ranish K.; Keith, Dove; Sousa, Megan; Minnier, Jessica; Kingston, Benjamin R.; David, Larry; Esener, Sadik C.; Sears, Rosalie C.; Lopez, Charles D.; Sheppard, Brett C.; Demirci, Utkan; Wong, Melissa H.; Fischer, Jared M.
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Highly multiplexed imaging reveals prognostic immune and stromal spatial biomarkers in breast cancer
errJCI INSIGHT
IF6.1
err2025-01-14
err0
errOAAI
errEng, Jennifer R.; Bucher, Elmar; Hu, Zhi; Walker, Cameron R.; Risom, Tyler; Angelo, Michael; Gonzalez-Ericsson, Paula; Sanders, Melinda E.; Chakravarthy, A. Bapsi; Pietenpol, Jennifer A.; Gibbs, Summer L.; Sears, Rosalie C.; Chin, Koei
err分享
err收藏
The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress聚合氟嘧啶CF10通过增加复制应激克服了胰腺导管腺癌细胞中5-FU的局限性
errCANCER BIOLOGY & THERAPY
IF4.6
err2024-11-08
err0
errOAAI
errFinan, Jennifer M.; Di Niro, Roberto; Park, Soon Young; Jeong, Kang Jin; Hedberg, Madeline D.; Smith, Alexander; Mccarthy, Grace A.; Haber, Alex O.; Muschler, John; Sears, Rosalie C.; Mills, Gordon B.; Gmeiner, William H.; Brody, Jonathan R.
err分享
err收藏
KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development
errONCOGENE
IF7.3
err2024-10-23
err0
PREAI
errTinsley, Samantha L.; Chianis, Ella Rose D.; Shelley, Rebecca A.; Mall, Gaganpreet K.; Dhiman, Alisha; Baral, Garima; Kothandaraman, Harish; Thoma, Mary C.; English, Isabel A.; Daniel, Colin J.; Acosta, Luis Carlos Sanjuan; Solorio, Luis; Lanman, Nadia Atallah; di Magliano, Marina Pasca; Narla, Goutham; Dykhuizen, Emily C.; Sears, Rosalie C.; Allen-Petersen, Brittany L.
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Suppression of dystroglycan function accompanies pancreatic acinar-to-ductal metaplasia and favours dysplasia development
errJOURNAL OF PATHOLOGY
IF5.2
err2024-10-22
err0
PREAI
errHuang, Ge; Ternes, Luke; Lanciault, Christian; MacPherson-Hawthorne, Kevin; Chang, Young Hwan; Sears, Rosalie C.; Muschler, John L.
err分享
err收藏
CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer卡斯珀: calaspargase pegol-mnkl和cobimetinib联合治疗胰腺癌的I期试验
errFUTURE ONCOLOGY
IF2.6
err2024-10-08
err0
PREAI
errLopez, Charles D.; Kardosh, Adel; Chen, Emerson Y.; Pegna, Guillaume; Guimaraes, Alexander; Foster, Bryan; Brinkerhoff, Brian; Goodyear, Shaun M.; Lim, Jeong-Youn; Taber, Erin; Rajagopalan, Brindha; Edmerson, Exodus; Vo, Johnson; Nelson, Katherine; Jackson, Anna; Gingerich, Tasha; Fahlman, Anne; Lessenich, Christopher; Fennell, Francesca; Ventura, Diane; Roy, Preeyam; Keith, Dove; Sheppard, Brett; Brody, Jonathan R.; Mills, Gordon B.; Ronai, Ze'ev A.; Sears, Rosalie C.
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研究方向

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合作学者
合作期刊
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Michael Karin
H 指数: 254 · 论文数: 904
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Gordon B. Mills
H 指数: 231 · 论文数: 3.5K
R
Ronald M. Evans
H 指数: 211 · 论文数: 926
C
Caroline Robert
H 指数: 154 · 论文数: 1.5K
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H 指数: 147 · 论文数: 1.1K
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