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Reduced inflammation and lymphocyte infiltration after reperfusion in triple knock-out porcine kidney xenografts expressing human transgenes transplanted to nonhuman primates. Karadagi, Ahmad; Rosales, Ivy; Hirose, Takayuki; Lassiter, Grace; Tomosugi, Toshihide; Otsuka, Ryo; Curtis, Michael; Chhangawala, Sagar; Low, Susan; Qin, Wenning; Colvin, Robert; Kawai, Tatsuo 分享 收藏
Design and creation of a clinically compatible porcine donor for xenotransplantation Qin, Wenning; Anand, Ranjith P.; Paragas, Violette B.; Layer, Jacob V.; Akkad, Adam; Pandelakis, Matthew; Yin, Shiyi; Chhangawala, Sagar; Policastro, Robert A.; Li, Feng; Guo, Xiaoyun; Xue, Yongqiang; Griffin, Alexander K.; Kan, Yinan; Ernst, Russell J.; Youd, Michele E.; Heja, David; Firl, Daniel J.; Low, Susan C.; Harken, Sierra; Kawai, Tatsuo; Hirose, Takayuki; Lassiter, Grace; Queiroz, Luis 分享 收藏
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression Anelli, Viviana; Villefranc, Jacques A.; Chhangawala, Sagar; Martinez-McFaline, Raul; Riva, Eleonora; Nguyen, Anvy; Verma, Akanksha; Bareja, Rohan; Chen, Zhengming; Scognamiglio, Theresa; Elemento, Olivier; Houvras, Yariv 分享 收藏
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility Dhara, S.; Chhangawala, S.; Chintalapudi, H.; Askan, G.; Aveson, V; Massa, A. L.; Zhang, L.; Torres, D.; Makohon-Moore, A. P.; Lecomte, N.; Melchor, J. P.; Bermeo, J.; Cardenas, A.; Sinha, S.; Glassman, D.; Nicolle, R.; Moffitt, R.; Yu, K. H.; Leppanen, S.; Laderman, S.; Curry, B.; Gui, J.; Balachandran, V. P.; Iacobuzio-Donahue, C.; Chandwani, R.; Leslie, C. S.; Leach, S. D. 分享 收藏
Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses 糖酵解ATP促进磷酸肌醇3-激酶信号传导以支持效应T辅助17细胞反应 Xu, Ke; Yin, Na; Peng, Min; Stamatiades, Efstathios G.; Chhangawala, Sagar; Shyu, Amy; Li, Peng; Zhang, Xian; Do, Mytrang H.; Capistrano, Kristelle J.; Chou, Chun; Leslie, Christina S.; Li, Ming O. 分享 收藏
Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction (vol 51, 766.e1, 2019) Abelin, Jennifer G.; Harjanto, Dewi; Malloy, Matthew; Suri, Prerna; Colson, Tyler; Goulding, Scott P.; Creech, Amanda L.; Serrano, Lia R.; Nasir, Gibran; Nasrullah, Yusuf; McGann, Christopher D.; Velez, Diana; Ting, Ying S.; Poran, Asaf; Rothenberg, Daniel A.; Chhangawala, Sagar; Rubinsteyn, Alex; Hammerbacher, Jeff; Gaynor, Richard B.; Fritsch, Edward F.; Greshock, Joel; Oslund, Rob C.; Barthelme, Dominik; Addona, Terri A.; Arieta, Christina M.; Rooney, Michael S. 分享 收藏
Pancreatic cancer prognosis is predicted by chromatin accessibility microarray Dhara, Surajit; Chhangawala, Sagar; Chintalapudi, Himanshu; Massa, Alexandra L.; Aveson, Victoria; Askan, Gokce; Zhang, Liguo; Nicolle, Remy; Makohon-Moore, Alvin P.; Sinha, Smrita; Gui, Jiang; Moffitt, Richard; Yu, Kenneth H.; Balachandran, Vinod; Chandwani, Rohit; Leslie, Christina; Leach, Steven D. 分享 收藏
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer Xu, Guotai; Chhangawala, Sagar; Cocco, Emiliano; Razavi, Pedram; Cai, Yanyan; Otto, Jordan E.; Ferrando, Lorenzo; Selenica, Pier; Ladewig, Erik; Chan, Carmen; Paula, Arnaud Da Cruz; Witkin, Matthew; Cheng, Yuanming; Park, Jane; Serna-Tamayo, Cristian; Zhao, HuiYong; Wu, Fan; Sallaku, Mirna; Qu, Xuan; Zhao, Alison; Collings, Clayton K.; D'Avino, Andrew R.; Jhaveri, Komal; Koche, Richard; Levine, Ross L.; Reis-Filho, Jorge S.; Kadoch, Cigall; Scaltriti, Maurizio; Leslie, Christina S.; Baselga, Jose; Toska, Eneda 分享 收藏
Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction Abelin, Jennifer G.; Harjanto, Dewi; Malloy, Matthew; Suri, Prerna; Colson, Tyler; Goulding, Scott P.; Creech, Amanda L.; Serrano, Lia R.; Nasir, Gibran; Nasrullah, Yusuf; McGann, Christopher D.; Velez, Diana; Ting, Ying S.; Poran, Asaf; Rothenberg, Daniel A.; Chhangawala, Sagar; Rubinsteyn, Alex; Hammerbacher, Jeff; Gaynor, Richard B.; Fritsch, Edward F.; Greshock, Joel; Oslund, Rob C.; Barthelme, Dominik; Addona, Terri A.; Arleta, Christina M.; Rooney, Michael S. 分享 收藏
ARID1A is a critical regulator of luminal identity and therapeutic response in estrogen receptor-positive breast cancer Toska, Eneda; Xu, Guotai; Chhangawala, Sagar; Cocco, Emiliano; Razavi, Pedram; Otto, Jordan; Cai, Yanyan; Chan, Carmen; Avino, Drew R. D'; Collings, Clayton; Levine, Ross L.; Scaltriti, Maurizo; Reis-Filho, Jorge S.; Kadoch, Cigall; Leslie, Christina; Baselga, Jose 分享 收藏
PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression Toska, Eneda; Castel, Pau; Chhangawala, Sagar; Arruabarrena-Aristorena, Amaia; Chan, Carmen; Hristidis, Vasilis C.; Cocco, Emiliano; Sallaku, Mirna; Xu, Guotai; Park, Jane; Minuesa, Gerard; Shifman, Sophie G.; Socci, Nicholas D.; Koche, Richard; Leslie, Christina S.; Scaltriti, Maurizio; Baselga, Jose 分享 收藏
IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation Park, Sun-Mi; Cho, Hyunwoo; Thornton, Angela M.; Barlowe, Trevor S.; Chou, Timothy; Chhangawala, Sagar; Fairchild, Lauren; Taggart, James; Chow, Arthur; Schurer, Alexandria; Gruet, Antoine; Witkin, Matthew D.; Kim, Jun Hyun; Shevach, Ethan M.; Krivtsov, Andrei; Armstrong, Scott A.; Leslie, Christina; Kharas, Michael G. 分享 收藏
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth Cox, Andrew G.; Tsomides, Allison; Yimlamai, Dean; Hwang, Katie L.; Miesfeld, Joel; Galli, Giorgio G.; Fowl, Brendan H.; Fort, Michael; Ma, Kimberly Y.; Sullivan, Mark R.; Hosios, Aaron M.; Snay, Erin; Yuan, Min; Brown, Kristin K.; Lien, Evan C.; Chhangawala, Sagar; Steinhauser, Matthew L.; Asara, John M.; Houvras, Yariv; Link, Brian; Vander Heiden, Matthew G.; Camargo, Fernando D.; Goessling, Wolfram 分享 收藏
Genome wide cis-regulatory elements accessibility signature predicts early recurrence of the treatment-naive resected subset of PDAC: A new paradigm for precision oncology Dhara, Surajit; Chhangawala, Sagar; Askan, Gokce; Liguo, Zhang; Sinha, Smrita; Glassman, Danielle; Yu, Kenneth; Balachandran, Vinod; Leslie, Christina; Leach, Steven 分享 收藏
Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma Venkatesan, Arvind M.; Vyas, Rajesh; Gramann, Alec K.; Dresser, Karen; Gujja, Sharvari; Bhatnagar, Sanchita; Chhangawala, Sagar; Gomes, Camilla Borges Ferreira; Xi, Hualin Simon; Lian, Christine G.; Houvras, Yariv; Edwards, Yvonne J. K.; Deng, April; Green, Michael; Ceol, Craig J. 分享 收藏
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells Vu, Ly P.; Prieto, Camila; Amin, Elianna M.; Chhangawala, Sagar; Krivtsov, Andrei; Calvo-Vidal, M. Nieves; Chou, Timothy; Chow, Arthur; Minuesa, Gerard; Park, Sun Mi; Barlowe, Trevor S.; Taggart, James; Tivnan, Patrick; Deering, Raquel P.; Chu, Lisa P.; Kwon, Jeong-Ah; Meydan, Cem; Perales-Paton, Javier; Arshi, Arora; Gonen, Mithat; Famulare, Christopher; Patel, Minal; Paietta, Elisabeth; Tallman, Martin S.; Lu, Yuheng; Glass, Jacob; Garret-Bakelman, Francine E.; Melnick, Ari; Levine, Ross; Al-Shahrour, Fatima; Jaras, Marcus; Hacohen, Nir; Hwang, Alexia; Garippa, Ralph; Lengner, Christopher J.; Armstrong, Scott A.; Cerchietti, Leandro; Cowley, Glenn S.; Root, David; Doench, John; Leslie, Christina; Ebert, Benjamin L.; Kharas, Michael G. 分享 收藏
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Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis Cox, Andrew G.; Tsomides, Allison; Kim, Andrew J.; Saunders, Diane; Hwang, Katie L.; Evason, Kimberley J.; Heidel, Jerry; Brown, Kristin K.; Yuan, Min; Lien, Evan C.; Lee, Byung Cheon; Nissim, Sahar; Dickinson, Bryan; Chhangawala, Sagar; Chang, Christopher J.; Asara, John M.; Houvras, Yariv; Gladyshev, Vadim N.; Goessling, Wolfram 分享 收藏
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth Cox, Andrew G.; Hwang, Katie L.; Brown, Kristin K.; Evason, Kimberley J.; Beltz, Sebastian; Tsomides, Allison; O'Connor, Keelin; Galli, Giorgio G.; Yimlamai, Dean; Chhangawala, Sagar; Yuan, Min; Lien, Evan C.; Wucherpfennig, Julia; Nissim, Sahar; Minami, Akihiro; Cohen, David E.; Camargo, Fernando D.; Asara, John M.; Houvras, Yariv; Stainier, Didier Y. R.; Goessling, Wolfram 分享 收藏
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