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S

Simon Cockell

newcastle university
H指数:34
被引数:5,596

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Differential BET protein recruitment to IL6 and IL8 promoters and suppression of inflammatory and cell cycle genes by BET inhibitor in keratinocytes

角化细胞中BET蛋白对IL6和IL8启动子的差异性募集以及BET抑制剂对炎症和细胞周期基因的抑制作用

Journal of Investigative Dermatology
IF5.7
2026-09-130
PRE
Keith C.P. Wu; Nicola R. Harker; Simon J. Cockell; John Casement; Michael J. Donaldson; Erika Cule; Paul A. Wilson; Rab K. Prinjha; Mary A. Morse; Nick J. Reynolds
Integrated multi-omics identifies distinct macrophage alterations during progression of metabolic dysfunction-associated steatohepatitis

整合多组学分析揭示代谢功能障碍相关脂肪性肝炎进展过程中巨噬细胞的特异性改变

Nature Genetics
IF29
2026-05-180
OAAI
Markus Boesch; Seray Anak; Dania El Abyad; Tessa Ostyn; Asier Antoranz; Trieu My Van; Daniel Newhouse; Caitlyn Myers; Lukas Van Melkebeke; Jeremy Palmer; Najmeh Saffarzadeh; Jonathan Sai-Hong Chui; Rita Feio-Azevedo; Lena Smets; Gautam Shankar; Nikolina Dubroja Lakić; Paula Longás Calvo; Thierry Voet; James Clark; Simon Cockell; Matthias Lannoo; Ellen Deleus; Joris Jaekers; Halit Topal; Baki Topal; Kai Markus Schneider; Michele Vacca; Michael Allison; Mattias Ekstedt; Jerome Boursier; Elisabetta Bugianesi; Vlad Ratziu; Frederik De Smet; Bram Boeckx; Ann K. Daly; Jörn M. Schattenberg; Jef Verbeek; Francesca Bosisio; Diether Lambrechts; Tania Roskams; Carolin V. Schneider; Sven Francque; Hannelie Korf; Anetta Härtlova; Dina Tiniakos; Quentin M. Anstee; Schalk van der Merwe; Olivier Govaere
Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha

通过选择性抑制IκB激酶α靶向CYLD皮肤综合征中的非经典NF-κB信号通路

British Journal of Dermatology
IF9.6
2026-03-040
OA
Kirsty Hodgson; Joseph Inns; Gary Reynolds; Emily Stephenson; Andrew Paul; Naomi Sinclair; Giacomo Berretta; Christopher Lawson; Andrew Michael Frey; Iglika Ivanova; Eva Adam; Christopher J Lord; Simon Cockell; Jonathan Coxhead; Nikoletta Nagy; David Adams; Marta Szell; Matthias Trost; Muzlifah Haniffa; Simon P Mackay; Neil Perkins; Neil Rajan; null
Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity

转录组分析和机器学习揭示银屑病内型和疾病严重程度的基因特征

Communications Medicine
IF6.3
2026-01-210
OAAI
Ashley Rider; Henry J. Grantham; Graham R. Smith; David S. Watson; John Casement; Simon J. Cockell; Jack Gisby; Amy C. Foulkes; Rafael Henkin; Wasim A. Iqbal; Tom Ewen; Shoba Amarnath; Sandra Ng; Paolo Zuliani; Nick Dand; Deborah Stocken; Christopher Traini; Elizabeth Thomas; Shanker Kalyana-Sundaram; Deepak K. Rajpal; Kathleen M. Smith; Jonathan N. Barker; Christopher E. M. Griffiths; Paola Di Meglio; Catherine H. Smith; Richard B. Warren; Michael R. Barnes; Nick J. Reynolds
An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression
ELIFE
IF0
2024-10-020
OA
Siachisumo, Chileleko; Luzzi, Sara; Aldalaqan, Saad; Hysenaj, Gerald; Dalgliesh, Caroline; Cheung, Kathleen; Gazzara, Matthew R.; Yonchev, Ivaylo D.; James, Katherine; Chadegani, Mahsa Kheirollahi; Ehrmann, Ingrid E.; Smith, Graham R.; Cockell, Simon J.; Munkley, Jennifer; Wilson, Stuart A.; Barash, Yoseph; Elliott, David J.
Pharmacogene expression during progression of metabolic dysfunction-associated steatotic liver disease: Studies on mRNA and protein levels and their relevance to drug treatment

代谢功能障碍相关脂肪变性肝病进展过程中的药理学表达: mRNA和蛋白质水平及其与药物治疗相关性的研究

BIOCHEMICAL PHARMACOLOGY
IF5.6
2024-10-012
OAAI
Govaere, Olivier; Cockell, Simon J.; Zatorska, Michalina; Wonders, Kristy; Tiniakos, Dina; Frey, Andrew M.; Palmowksi, Pawel; Walker, Ruth; Porter, Andrew; Trost, Matthias; Anstee, Quentin M.; Daly, Ann K.
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

肠道b细胞许可NASH微生物群中代谢T细胞活化/抗原独立，并通过IgA-FcR信号传导促进纤维化

JOURNAL OF HEPATOLOGY
IF33
2023-08-0137
OAAI
Kotsiliti, Elena; Leone, Valentina; Schuehle, Svenja; Govaere, Olivier; Li, Hai; Wolf, Monika J.; Horvatic, Helena; Bierwirth, Sandra; Hundertmark, Jana; Inverso, Donato; Zizmare, Laimdota; Sarusi-Portuguez, Avital; Gupta, Revant; O'Connor, Tracy; Giannou, Anastasios D.; Shiri, Ahmad Mustafa; Schlesinger, Yehuda; Beccaria, Maria Garcia; Rennert, Charlotte; Pfister, Dominik; Oellinger, Rupert; Gadjalova, Iana; Ramadori, Pierluigi; Rahbari, Mohammad; Rahbari, Nuh; Healy, Marc E.; Fernandez-Vaquero, Mirian; Yahoo, Neda; Janzen, Jakob; Singh, Indrabahadur; Fan, Chaofan; Liu, Xinyuan; Rau, Monika; Feuchtenberger, Martin; Schwaneck, Eva; Wallace, Sebastian J.; Cockell, Simon; Wilson-Kanamori, John; Ramachandran, Prakash; Kho, Celia; Kendall, Timothy J.; Leblond, Anne-Laure; Keppler, Selina J.; Bielecki, Piotr; Steiger, Katja; Hofmann, Maike; Rippe, Karsten; Zitzelsberger, Horst; Weber, Achim; Malek, Nisar; Luedde, Tom; Vucur, Mihael; Augustin, Hellmut G.; Flavell, Richard; Parnas, Oren; Rad, Roland; Pabst, Olivier; Henderson, Neil C.; Huber, Samuel; Macpherson, Andrew; Knolle, Percy; Claassen, Manfred; Geier, Andreas; Trautwein, Christoph; Unger, Kristian; Elinav, Eran; Waisman, Ari; Abdullah, Zeinab; Haller, Dirk; Tacke, Frank; Anstee, Quentin M.; Heikenwalder, Mathias
Genome-wide association study of non- alcoholic fatty liver and steatohepatitis in a histologically characterised cohort( vol 73, pp 505-515 , 2020 )
JOURNAL OF HEPATOLOGY
IF33
2023-05-012
OA
Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Joern M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K.
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance
JHEP REPORTS
IF7.5
2022-02-0131
OAAI
Johnson, Katherine; Leary, Peter J.; Govaere, Olivier; Barter, Matthew J.; Charlton, Sarah H.; Cockell, Simon J.; Tiniakos, Dina; Zatorska, Michalina; Bedossa, Pierre; Brosnan, M. Julia; Cobbold, Jeremy F.; Ekstedt, Mattias; Aithal, Guruprasad P.; Clement, Karine; Schattenberg, Joern M.; Boursier, Jerome; Ratziu, Vlad; Bugianesi, Elisabetta; Anstee, Quentin M.; Daly, Ann K.
A de novo paradigm for male infertility
NATURE COMMUNICATIONS
IF15.7
2022-01-1047
OAAI
Oud, M. S.; Smits, R. M.; Smith, H. E.; Mastrorosa, F. K.; Holt, G. S.; Houston, B. J.; de Vries, P. F.; Alobaidi, B. K. S.; Batty, L. E.; Ismail, H.; Greenwood, J.; Sheth, H.; Mikulasova, A.; Astuti, G. D. N.; Gilissen, C.; McEleny, K.; Turner, H.; Coxhead, J.; Cockell, S.; Braat, D. D. M.; Fleischer, K.; D'Hauwers, K. W. M.; Schaafsma, E.; Nagirnaja, L.; Conrad, D. F.; Friedrich, C.; Kliesch, S.; Aston, K. I.; Riera-Escamilla, A.; Krausz, C.; Gonzaga-Jauregui, C.; Santibanez-Koref, M.; Elliott, D. J.; Vissers, L. E. L. M.; Tuettelmann, F.; O'Bryan, M. K.; Ramos, L.; Xavier, M. J.; van der Heijden, G. W.; Veltman, J. A.
Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis

转录组学将Thrombospondin-2鉴定为NASH和晚期肝纤维化的生物标志物

HEPATOLOGY
IF15.8
2021-08-2184
OAAI
Kozumi, Kazuhiro; Kodama, Takahiro; Murai, Hiroki; Sakane, Sadatsugu; Govaere, Olivier; Cockell, Simon; Motooka, Daisuke; Kakita, Naruyasu; Yamada, Yukinori; Kondo, Yasuteru; Tahata, Yuki; Yamada, Ryoko; Hikita, Hayato; Sakamori, Ryotaro; Kamada, Yoshihiro; Daly, Ann K.; Anstee, Quentin M.; Tatsumi, Tomohide; Morii, Eiichi; Takehara, Tetsuo
Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort (vol 12, pg 505, 2020)
JOURNAL OF HEPATOLOGY
IF33
2021-05-015
PREAI
Anstee, Quentin M.; Darlay, Rebecca; Cockell, Simon; Meroni, Marica; Govaere, Olivier; Tiniakos, Dina; Burt, Alastair D.; Bedossa, Pierre; Palmer, Jeremy; Liu, Yang-Lin; Aithal, Guruprasad P.; Allison, Michael; Yki-Jarvinen, Hannele; Vacca, Michele; Dufour, Jean-Francois; Invernizzi, Pietro; Prati, Daniele; Ekstedt, Mattias; Kechagias, Stergios; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Clement, Karine; Ratziu, Vlad; Schattenberg, Jorn M.; Valenti, Luca; Day, Christopher P.; Cordell, Heather J.; Daly, Ann K.

研究方向

暂未获取到该数据
Q
Quentin M. Anstee
H 指数:110论文数:607被引数:6.8万
O
Olivier Govaere
H 指数:47论文数:169被引数:1.1万
A
Ann K. Daly
H 指数:96论文数:506被引数:3.4万
J
Jörn M. Schattenberg
H 指数:78论文数:820被引数:3.2万
M
Mattias Ekstedt
H 指数:44论文数:217被引数:1.6万
E
Elisabetta Bugianesi
H 指数:113论文数:677被引数:7.4万
D
Dina Tiniakos
H 指数:57论文数:331被引数:1.4万
V
Vlad Ratziu
H 指数:107论文数:698被引数:6.3万
P
Pierre Bédossa
H 指数:121论文数:888被引数:7.1万
J
Jonathan Coxhead
H 指数:32论文数:105被引数:5,298