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F

Frank J. Beurskens

genmab
H指数:35
被引数:5,793

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Logic-gated antibody pairs that selectively act on cells co-expressing two antigens
NATURE BIOTECHNOLOGY
IF41.7
2022-07-2519
OAAI
Oostindie, Simone C.; Rinaldi, Derek A.; Zom, Gijs G.; Wester, Michael J.; Paulet, Desiree; Al-Tamimi, Kusai; van der Meijden, Els; Scheick, Jennifer R.; Wilpshaar, Tessa; de Jong, Bart; Hoff-van den Broek, Marloes; Grattan, Rachel M.; Oosterhoff, Janita J.; Vignau, Julie; Verploegen, Sandra; Boross, Peter; Beurskens, Frank J.; Lidke, Diane S.; Schuurman, Janine; de Jong, Rob N.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases

C1q与表面结合的IgG的结合被C1r2s2蛋白酶稳定

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-06-2136
OAAI
Zwarthoff, Seline A.; Widmer, Kevin; Kuipers, Annemarie; Strasser, Jurgen; Ruyken, Maartje; Aerts, Piet C.; de Haas, Carla J. C.; Ugurlar, Deniz; den Boer, Maurits A.; Vidarsson, Gestur; van Strijp, Jos A. G.; Gros, Piet; Parren, Paul W. H., I; van Kessel, Kok P. M.; Preiner, Johannes; Beurskens, Frank J.; Schuurman, Janine; Ricklin, Daniel; Rooijakkers, Suzan H. M.
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation

葡萄球菌蛋白A通过干扰IgG六聚体形成来抑制补体激活

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-02-0969
OAAI
Cruz, Ana Rita; den Boer, Maurits A.; Strasser, Jurgen; Zwarthoff, Seline A.; Beurskens, Frank J.; de Haas, Carla J. C.; Aerts, Piet C.; Wang, Guanbo; de Jong, Rob N.; Bagnoli, Fabio; van Strijp, Jos A. G.; van Kessel, Kok P. M.; Schuurman, Janine; Preiner, Johannes; Heck, Albert J. R.; Rooijakkers, Suzan H. M.
Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism
MOLECULAR CANCER THERAPEUTICS
IF5.5
2020-10-0240
OAAI
Overdijk, Marije B.; Strumane, Kristin; Beurskens, Frank J.; Buijsse, Antonio Ortiz; Vermot-Desroches, Claudine; Vuillermoz, Boris S.; Kroes, Thessa; de Jong, Bart; Hoevenaars, Naomi; Hibbert, Richard G.; Lingnau, Andreas; Forssmann, UIf; Schuurman, Janine; Parren, Paul W. H., I; de Jong, Rob N.; Breij, Esther C. W.
Multifaceted mechanism of action of DuoHexaBody-CD37 involves both complement- and Fc gamma receptor-mediated cytotoxicity in pre-clinical B-cell lymphoma models
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Kil, Laurens P.; Oostindie, Simone C.; Strumane, Kristin; van der Horst, Hilma J.; van Kessel, Berris; Overdijk, Marije B.; Lingnau, Andreas; Brandhorst, Marcel; van den Brakel, Jeroen; Lindorfer, Margaret A.; Taylor, Ronald P.; Chamuleau, Martine E.; Mutis, Tuna; Sasser, A. Kate; Schuurman, Janine; Parren, Paul W.; Beurskens, Frank J.; Breij, Esther C.
DuoHexaBody-CD37(R), a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies
BLOOD CANCER JOURNAL
IF11.6
2020-04-2847
OAAI
Oostindie, Simone C.; van der Horst, Hilma J.; Kil, Laurens P.; Strumane, Kristin; Overdijk, Marije B.; van den Brink, Edward N.; van den Brakel, Jeroen H. N.; Rademaker, Hendrik J.; van Kessel, Berris; van den Noort, Juliette; Chamuleau, Martine E. D.; Mutis, Tuna; Lindorfer, Margaret A.; Taylor, Ronald P.; Schuurman, Janine; Parren, Paul W. H. I.; Beurskens, Frank J.; Breij, Esther C. W.

研究方向

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P
Paul W.H.I. Parren
H 指数:96论文数:474被引数:3.1万
J
Janine Schuurman
H 指数:46论文数:167被引数:9,407
R
Ronald P. Taylor
H 指数:52论文数:311被引数:1.0万
R
Rob N. de Jong
H 指数:32论文数:114被引数:4,318
M
Margaret A. Lindorfer
H 指数:47论文数:132被引数:6,593
E
Esther C.W. Breij
H 指数:24论文数:153被引数:3,056
J
Jan G. J. van de Winkel
H 指数:79论文数:402被引数:2.2万
S
Simone C. Oostindie
H 指数:10论文数:18被引数:903
K
Kristin Strumane
H 指数:16论文数:69被引数:2,585
T
Thomas Valerius
H 指数:47论文数:349被引数:7,327