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Wastewater Measures of SARS-CoV-2 Accurately Predict Frequency of Symptomatic Infections in the Community SARS-CoV-2废水检测措施可准确预测社区内症状性感染的频率 Doss, Charles R.; Osborn, Mark J.; Stark, Stacey; Rhein, Joshua; Donkersgoed, Jacalynn; Budde, Donna; Champeau, Shannon; Meyer, Carolyn; Hayden, Mason; Landini, Laura; Ouyang, Difan; Chung, Lappui; Tang, Yi; Vetter, Sara; Schacker, Timothy W. 分享 收藏
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase 利用实验室进化型CRISPR相关转座酶在人类细胞中进行可编程基因插入 Witte, Isaac P.; Lampe, George D.; Eitzinger, Simon; Miller, Shannon M.; Berrios, Kiara N.; McElroy, Amber N.; King, Rebeca T.; Stringham, Olivia G.; Gelsinger, Diego R.; Vo, Phuc Leo H.; Chen, Albert T.; Tolar, Jakub; Osborn, Mark J. 分享 收藏
Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa 双胞胎Prime编辑介导的外显子跳跃/重新插入可恢复隐性营养不良性大疱性表皮松解症中胶原蛋白VII的表达 Steinbeck, Benjamin J.; Gao, Xin D.; Mcelroy, Amber N.; Pandey, Smriti; Doman, Jordan L.; Riddle, Megan J.; Xia, Lily; Chen, Weili; Eide, Cindy R.; Lengert, Andre H.; Han, Sang Won; Blazar, Bruce R.; Wandall, Hans H.; Dabelsteen, Sally; Liu, David R.; Tolar, Jakub; Osborn, Mark J. 分享 收藏
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing 通过不断进化的重组酶和主要编辑，在哺乳动物细胞中有效地进行大基因的位点特异性整合 Pandey, Smriti; Gao, Xin D.; Krasnow, Nicholas A.; McElroy, Amber; Tao, Y. Allen; Duby, Jordyn E.; Steinbeck, Benjamin J.; McCreary, Julia; Pierce, Sarah E.; Tolar, Jakub; Meissner, Torsten B.; Chaikof, Elliot L.; Osborn, Mark J.; Liu, David R. 分享 收藏
Wastewater Surveillance of SARS-CoV-2 in Minnesota Osborn, Mark J.; Champeau, Shannon; Meyer, Carolyn; Hayden, Mason; Landini, Laura; Stark, Stacey; Preekett, Stephanie; Vetter, Sara; Zirnhelt, Zachary; Meyer, Stephanie; Huff, Daniel; Schacker, Timothy W.; Doss, Charles R. 分享 收藏
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity 小鼠调节性T细胞的强制肠道归巢可降低早期移植物抗宿主病的严重程度 Larson, Jemma H.; Jin, Sujeong; Loschi, Michael; Wagers, Sara Bolivar; Thangavelu, Govindarajan; Zaiken, Michael C.; McDonald-Hyman, Cameron; Saha, Asim; Aguilar, Ethan G.; Koehn, Brent; Osborn, Mark J.; Panoskaltsis-Mortari, Angela; Macdonald, Kelli P. A.; Hill, Geoffrey R.; Murphy, William J.; Serody, Jonathan S.; Maillard, Ivan; Kean, Leslie S.; Kim, Sangwon, V; Littman, Dan R.; Blazar, Bruce R. 分享 收藏
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity 腺嘌呤碱基编辑器演变为具有低脱靶活性的小型高效胞嘧啶碱基编辑器 Neugebauer, Monica E.; Hsu, Alvin; Arbab, Mandana; Krasnow, Nicholas A.; McElroy, Amber N.; Pandey, Smriti; Doman, Jordan L.; Huang, Tony P.; Raguram, Aditya; Banskota, Samagya; Newby, Gregory A.; Tolar, Jakub; Osborn, Mark J.; Liu, David R. 分享 收藏
Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses 鼠CAR19 Tregs抑制急性移植物抗宿主病并维持移植物抗肿瘤反应 Bolivar-Wagers, Sara; Loschi, Michael L.; Jin, Sujeong; Thangavelu, Govindarajan; Larson, Jemma H.; McDonald-Hyman, Cameron S.; Aguilar, Ethan A.; Saha, Asim; Koehn, Brent H.; Hefazi, Mehrdad; Osborn, Mark J.; Jensen, Michael C.; Wagner, John E.; Pennell, Christopher A.; Blazar, Bruce R. 分享 收藏
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Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing Knipping, Friederike; Newby, Gregory A.; Eide, Cindy R.; McElroy, Amber N.; Nielsen, Sarah C.; Smith, Kyle; Fang, Yongxing; Cornu, Tatjana, I; Costa, Caroline; Gutierrez-Guerrero, Alejandra; Bingea, Samuel P.; Feser, Colby J.; Steinbeck, Benjamin; Hippen, Keli L.; Blazar, Bruce R.; McCaffrey, Anton; Mussolino, Claudio; Verhoeyen, Els; Tolar, Jakub; Liu, David R.; Osborn, Mark J. 分享 收藏
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Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion Hippen, Keli L.; Furlan, Scott N.; Roychoudhuri, Rahul; Wang, Ena; Zhang, Yigang; Osborn, Mark J.; Merkel, Sarah C.; Hani, Sophia; MacMillan, Margaret L.; Cichocki, Frank; Miller, Jeffrey S.; Wagner, John E.; Restifo, Nicholas P.; Kean, Leslie S.; Blazar, Bruce R. 分享 收藏
CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics Osborn, Mark J.; Bhardwaj, Akshay; Bingea, Samuel P.; Knipping, Friederike; Feser, Colby J.; Lees, Christopher J.; Collins, Daniel P.; Steer, Clifford J.; Blazar, Bruce R.; Tolar, Jakub 分享 收藏
Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs Osborn, Mark J.; Newby, Gregory A.; McElroy, Amber N.; Knipping, Friederike; Nielsen, Sarah C.; Riddle, Megan J.; Xia, Lily; Chen, Weili; Eide, Cindy R.; Webber, Beau R.; Wandall, Hans H.; Dabelsteen, Sally; Blazar, Bruce R.; Liu, David R.; Tolar, Jakub 分享 收藏
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors (vol 10, 5222, 2019) Webber, Beau R.; Lonetree, Cara-lin; Kluesner, Mitchell G.; Johnson, Matthew J.; Pomeroy, Emily J.; Diers, Miechaleen D.; Lahr, Walker S.; Draper, Garrett M.; Slipek, Nicholas J.; Smeester, Branden A.; Lovendahl, Klaus N.; McElroy, Amber N.; Gordon, Wendy R.; Osborn, Mark J.; Moriarity, Branden S. 分享 收藏
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors Webber, Beau R.; Lonetree, Cara-lin; Kluesner, Mitchell G.; Johnson, Matthew J.; Pomeroy, Emily J.; Diers, Miechaleen D.; Lahr, Walker S.; Draper, Garrett M.; Slipek, Nicholas J.; Smeester, Branden S.; Lovendahl, Klaus N.; McElroy, Amber N.; Gordon, Wendy R.; Osborn, Mark J.; Moriarity, Branden S. 分享 收藏
Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy Kim, Yoon-Myung; Yum, Mi-Sun; Heo, Sun Hee; Kim, Taeho; Jin, Hee Kyung; Bae, Jae-sung; Seo, Go Hun; Oh, Arum; Yoon, Hee Mang; Lim, Hyun Taek; Kim, Hyo-Won; Ko, Tae-Sung; Lim, Hyeong-Seok; Osborn, Mark J.; Tolar, Jakub; Cozma, Claudia; Rolfs, Arndt; Zimran, Ari; Lee, Beom Hee; Yoo, Han-Wook 分享 收藏
Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality 供体和宿主B7-H4表达负调节急性移植物抗宿主病致死率 Saha, Asim; Taylor, Patricia A.; Lees, Christopher J.; Panoskaltsis-Mortari, Angela; Osborn, Mark J.; Feser, Colby J.; Thangavelu, Govindarajan; Melchinger, Wolfgang; Refaeli, Yosef; Hill, Geoffrey R.; Munn, David H.; Murphy, William J.; Serody, Jonathan S.; Maillard, Ivan; Kreymborg, Katharina; van den Brink, Marcel; Dong, Chen; Huang, Shuyu; Zang, Xingxing; Allison, James P.; Zeiser, Robert; Blazar, Bruce R. 分享 收藏
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