何

何林洪 (Linhong He)

School of Pharmacy

H指数:15

被引数:609

个人简介

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教育背景

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工作经历

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荣誉奖项

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FOXC1 drives lung cancer metastasis and functions as a target for AI-enabled anti-metastatic drug discovery

FOXC1驱动肺癌转移并作为AI赋能的抗转移药物发现的靶点

Frontiers in Pharmacology

IF4.8

2026-09-100

Induction and propagation of ferroptosis evasion by FTH1P7 drives sorafenib resistance in hepatocellular carcinoma

FTH1P7介导的铁死亡逃避的诱导与传播驱动肝细胞癌对索拉非尼的耐药性

European Journal of Pharmacology

IF4.7

2026-08-030

PRE

Nanopore Discriminating d-Glucose Enantiomer Using a Designed Chiral Receptor

使用设计的手性受体区分d-葡萄糖对映异构体的纳米孔

Analytical Chemistry

IF6.7

2026-05-110

PRE

Design, Synthesis, and Mechanism Study of Novel BMX Inhibitors Based on the Core of 1,3,5-Triazin-2-Amine for the Treatment of Gastric Carcinoma

基于1,3,5-三嗪-2-胺核心的新型BMX抑制剂的设计、合成及其作用机制研究：用于治疗胃癌

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-02-151

PRE

FTH1P8 induces and transmits docetaxel resistance by inhibiting ferroptosis in prostate cancer

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-11-010

OAAI

Development of novel nitric oxide production inhibitors based on the 7H-pyrrolo[2,3-d]pyrimidine scaffold

MOLECULAR DIVERSITY

IF3.8

2024-05-060

PRE

Detection of the freshness of rice by chemiluminescence

LUMINESCENCE

IF3

2023-01-032

PRE

Association between Dietary Theobromine and Cognitive Function in a Representative American Population: A Cross-Sectional Study

JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE

IF7.8

2022-07-015

PRE

Engineering highly efficient Li+ responsive nanochannels via host-guest interaction and photochemistry regulation

JOURNAL OF COLLOID AND INTERFACE SCIENCE

IF9.7

2022-06-0110

PRE

New high-spin structure and possible chirality in 109In (vol 98, 014304, 2018)

PHYSICAL REVIEW C

IF3.4

2020-12-140

Design, synthesis, and biological evaluation of quinazoline derivatives as dual HDAC1 and HDAC6 inhibitors for the treatment of cancer

喹唑啉类化合物HDAC1和HDAC6双重抑制剂的设计、合成及生物活性评价

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2018-10-2825

PREAI

Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis

SCIENTIFIC REPORTS

IF3.9

2018-03-2734

OAAI

Design, synthesis, and SAR study of highly potent, selective, irreversible covalent JAK3 inhibitors

高效，选择性，不可逆共价JAK3抑制剂的设计，合成和SAR研究

MOLECULAR DIVERSITY

IF3.8

2018-02-0613

PREAI

Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d] pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-02-0118

PREAI

Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-09-0131

PREAI

Discovery of 5-methyl-2-(4-((4-(methylsulfonyl)benzyl)oxy)phenyl)-4-(piperazin-1-yl)pyrimidine derivatives as novel GRP119 agonists for the treatment of diabetes and obesity

MOLECULAR DIVERSITY

IF3.8

2017-06-2710

PREAI

Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening

在基于对接的虚拟筛选中使用多个晶体结构发现新型CDK8抑制剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-03-0132

PREAI

Discovery of a Potent 9-Deazaxanthine-based Agent for the Treatment of Obesity-Related Non-alcoholic Fatty Liver Disease

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2015-05-141

PREAI

Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases

新型5-苄基噻唑烷-2，4-二酮衍生物作为iNOS抑制剂对炎症性疾病的结构探索，合成和药理评价

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-03-0149

PREAI

Synthesis and lipid-lowering evaluation of 3-methyl-1H-purine-2,6-dione derivatives as potent and orally available anti-obesity agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-11-017

PREAI

何林洪 (Linhong He)

个人简介

教育背景

工作经历

荣誉奖项

研究方向