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Thorsten Lehr

Saarland University

35H指数
194论文数
6.3K被引数
收录论文 94
发表时间
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Physicochemical interactions between oral drug products: An integrated in vitro and PBPK modeling approach口腔药物制剂间的物理化学相互作用：一种集成的体外和PBPK建模方法
errInternational Journal of Pharmaceutics
IF5.2
err2026-09-04
err0
PREAI
errChristopher Hauß; Denise Feick; Dominik Selzer; Alvaro Lopez Marmol; Fabian Winter; Thorsten Lehr; Mirko Koziolek
err分享
err收藏
Positive net antiviral benefit of bexarotene against patient-derived archetype and rearranged BK polyomavirus isolates贝沙罗汀对来源于患者的原型和重排BK多瘤病毒分离株具有正向的净抗病毒益处。
errAntiviral Research
IF4
err2026-03-19
err0
PREAI
errPascal Feld; Lise Lauterbach-Rivière; Katharina Martha Götz; Lina Kathrin Toews; Lucia Thuringer; Matthias Sommer; Jessica Schüssler; Martin Janssen; Michael Stöckle; David Schmit; Danilo Fliser; Thorsten Lehr; Sigrun Smola
err分享
err收藏
Multinational cost-utility analysis of panel-based pharmacogenetics-guided treatment of patients enrolled in the U-PGx PREPARE study跨国成本-效用分析：基于U-PGx PREPARE研究中入组患者的药理学基因指导治疗
erreClinicalMedicine
IF10
err2025-12-16
err0
errOAAI
errVasileios Fragoulakis; Jesse J. Swen; Margarita-Ioanna Koufaki; Kathrin Blagec; Tanja Blagus; Stefan Böhringer; Anne Cambon-Thomsen; Erika Cecchin; Ka-Chun Cheung; Vera H.M. Deneer; Mathilde Dupui; Siv Jonsson; Candace Joefield-Roka; Katja S. Just; Mats O. Karlsson; Lidija Konta; Rudolf Koopmann; Marjolein Kriek; Thorsten Lehr; Lisanne E.N. Manson
err分享
err收藏
Advancing Rare Disease Therapeutics Through Digital Twins: Opportunities in Drug Development and Precision Dosing通过数字孪生推进罕见病治疗：药物研发和精准给药的机遇
errComputational and Structural Biotechnology Journal
IF4.1
err2025-11-23
err0
errOAAI
errCharlotte Maria Ursula Dette; Veronika Alberg; Simeon Rüdesheim; Dominik Selzer; Fatima Zahra Marok; Nicola Luigi Bragazzi; Laura Maria Fuhr; Søren Brunak; Ewan R. Pearson; Tobias Zahn; Dimitra Kiritsi; Matthias Schwab; Thorsten Lehr
err分享
err收藏
Safety and efficacy of monoclonal antibody therapy in patients with chronic herpes simplex virus-2 genital infections: MATCH-2, a randomized double-blinded, parallel-group phase 2 multi-center trial慢性单纯疱疹病毒-2生殖器感染患者中单克隆抗体疗法的安全性与有效性：MATCH-2，一项随机、双盲、平行组设计的多中心Ⅱ期临床试验
errPharmacological Research
IF10.5
err2025-10-16
err0
errOAAI
errHans-Jürgen Stellbrink; Torsten Schaller; Kerstin Sturm; Norbert H. Brockmeyer; Anja Potthoff; Markus Bickel; Stefan Scholten; Nils Postel; Arne Jessen; Matthias Müller; Dirk Jäger; Christian Müller; Narges Seyfizadeh; Stefan Schöffel; Bernd Ullrich; Laura Brosi; Claudia Kunz; Daniel Thomas; Rico Laage; Frank Hanakam; Matthias Schwab; Oliver Schönborn-Kellenberger; Marina Mangold; Katharina Och; Thorsten Lehr; Michaela A. Arndt; Jürgen Krauss
err分享
err收藏
987e: BIOMARKER-INFORMED THERAPY GUIDANCE IMPROVED CLINICAL OUTCOMES OF ANTI-TNF TREATMENT IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN A MULTI-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE CLINICAL TRIAL (GUIDE-IBD)987e: 生物标志物指导的疗法改善了炎症性肠病患者抗-TNF治疗的临床结局，该研究在一项多中心、随机、开放标签、前瞻性临床试验（GUIDE-IBD）中进行。
errGastroenterology
IF25.1
err2025-07-03
err0
PREAI
errFlorian Tran; Konrad Aden; Joana P. Bernardes; Charlot Jäckel; Christina Kovar; Simeon Rüdesheim; Marina Florea; Franziska Stallbaum; Florian Schrinner; Susanna Nikolaus; Walter Mätzler; Andre Franke; Silke Szymczak; Ute Hofmann; Thorsten Lehr; Matthias Schwab; Astrid Dempfle; Samuel Huber; Miriam Wiestler; Ursula Seidler; Stefan Schreiber
err分享
err收藏
Pharmacogenetic Implementation Studies—Lessons Learned From the PREPARE Study药物基因组学实施研究——来自PREPARE研究的经验教训
errClinical Pharmacology & Therapeutics
IF5.5
err2025-06-24
err0
errOAAI
errHenk-Jan Guchelaar; Cathelijne H. van der Wouden; Lisanne E. N. Manson; Heshu Abdullah-Koolmees; Kathrin Blagec; Tanja Blagus; Stefan Böhringer; Erika Cecchin; Ka-Chun Cheung; Vera H. M. Deneer; Siv Jonsson; Candace Joefield-Roka; Katja S. Just; Mats O. Karlsson; Lidija Konta; Rudolf Koopmann; Marjolein Kriek; Thorsten Lehr; Christina Mitropoulou; Victoria Rollinson; Rossana Roncato; Matthias Samwald; Elke Schaeffeler; Maria Skokou; Matthias Schwab; Daniela Steinberger; Julia C. Stingl; Roman Tremmel; Richard M. Turner; Mandy H. van Rhenen; Cristina L. Dávila-Fajardo; Vita Dolžan; George P. Patrinos; Munir Pirmohamed; Gere Sunder-Plassmann; Giuseppe Toffoli; Jesse J. Swen; Ubiquitous Pharmacogenomics Consortium
err分享
err收藏
Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug–Drug Interaction Predictions基于生理学的富莫奈替及其主要代谢物的药代动力学模型开发与验证：用于药物相互作用预测
errcpt pharmacometrics systems pharmacology
IF0
err2025-06-17
err0
errOAAI
errYali Wu; Helena Leonie Hanae Loer; Yifan Zhang; Dafang Zhong; Yong Jiang; Jie Hu; Uwe Fuhr; Thorsten Lehr; Xingxing Diao
err分享
err收藏
Population pharmacokinetics of intravenous fosfomycin: dose optimization for critically ill patients with and without kidney replacement therapy静脉注射磷霉素的群体药代动力学：接受与未接受肾脏替代治疗的危重患者的剂量优化
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2025-06-04
err0
errOAAI
errGoetz, Katharina M.; Kreuer, Sascha; Volz, Anke-Katrin; Parker, Suzanne L.; Roberts, Jason A.; Dimopoulos, George; Dimski, Thomas; Kindgen-Milles, Detlef; Beuche, Lisa K. V.; Kielstein, Jan T.; Lehr, Thorsten
err分享
err收藏
Effects of an interprofessional care concept in nursing homes evaluated in the SaarPHIR project: A cluster-randomized controlled trial在SaarPHIR项目中评估的跨专业护理概念对养老院的影响：一项集群随机对照试验
errPLOS ONE
IF2.6
err2025-05-15
err0
errOAAI
errToennies, Lisa; Zimmer, Viola; Piotrowski, Alexandra; Lehr, Thorsten; Laag, Sonja; Koeberlein-Neu, Juliane
err分享
err收藏
A Comprehensive CYP2D6 Drug-Drug-Gene Interaction Network for Application in Precision Dosing and Drug Development
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-02-14
err0
errOAAI
errRuedesheim, Simeon; Loer, Helena Leonie Hanae; Feick, Denise; Marok, Fatima Zahra; Fuhr, Laura Maria; Selzer, Dominik; Teutonico, Donato; Schneider, Annika R. P.; Solodenko, Juri; Frechen, Sebastian; van Der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Schwab, Matthias; Lehr, Thorsten
err分享
err收藏
Model-Based Prediction of Clinically Relevant Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-02-06
err0
errOAAI
errGoetz, Katharina M.; Turki, Amin T.; Och, Katharina; Selzer, Dominik; Brossette, Christian; Graf, Norbert; Rauch, Jochen; Theobald, Stefan; Braun, Yvonne; Rohm, Kerstin; Weiler, Gabriele; Ruedesheim, Simeon; Schwab, Matthias; Eisenberg, Lisa; Pfeifer, Nico; Kiefer, Stephan; Schwarz, Ulf; Riede, Claudia; Smola, Sigrun; Beelen, Dietrich W.; Kaddu-Mulindwa, Dominic; Rissland, Juergen; Bittenbring, Joerg; Lehr, Thorsten
err分享
err收藏
Client satisfaction, safety, and insights from a three-season survey on influenza vaccinations delivered at community pharmacies in Germany客户满意度、安全性及来自德国社区药房实施流感疫苗接种的三季调查的见解
errVACCINE
IF3.5
err2025-01-01
err1
errOAAI
errWerthner, Quirin; Faehrmann, Laura; Och, Katharina; Bragazzi, Nicola Luigi; Hug, Martin Johannes; Stahmeyer, Jona; Burger, Birte; Bauer, Cosima; Selzer, Dominik; Schwalbe, Oliver; May, Uwe; Lehr, Thorsten
err分享
err收藏
Does a carboxamide moiety alter the toxicokinetics of synthetic cannabinoids? A study after pulmonary and intravenous administration of cumyl-5F-P7AICA to pigs
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-12-04
err0
errOAAI
errWalle, Nadja; Dings, Christiane; Zaher, Omar; Doerr, Adrian A.; Peters, Benjamin; Laschke, Matthias W.; Lehr, Thorsten; Menger, Michael D.; Schmidt, Peter H.; Meyer, Markus R.; Schaefer, Nadine
err分享
err收藏
Effect of vaccinations and school restrictions on the spread of COVID-19 in different age groups in Germany
errINFECTIOUS DISEASE MODELLING
IF2.5
err2024-12-01
err0
errOAAI
errDings, Christiane; Selzer, Dominik; Bragazzi, Nicola Luigi; Moehler, Eva; Wenning, Markus; Gehrke, Thomas; Richter, Ulf; Nonnenmacher, Alexandra; Brinkmann, Folke; Rothoeft, Tobias; Zemlin, Michael; Lucke, Thomas; Lehr, Thorsten
err分享
err收藏
Toxicokinetic modelling of the synthetic cannabinoid 5F-MDMB-P7AICA and its main metabolite in pigs following pulmonary administration
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2024-11-21
err2
errOAAI
errDoerr, Adrian A.; Dings, Christiane; Zaher, Omar; Nordmeier, Frederike; Walle, Nadja; Laschke, Matthias W.; Menger, Michael D.; Schmidt, Peter H.; Meyer, Markus R.; Lehr, Thorsten; Schaefer, Nadine
err分享
err收藏
Exploring the Potential of Adaptive, Local Machine Learning in Comparison to the Prediction Performance of Global Models: A Case Study from Bayer's Caco-2 Permeability Database
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-11-20
err0
errOAAI
errSteinbauer, Frank Filip; Lehr, Thorsten; Reichel, Andreas
err分享
err收藏
Efficacy and safety of asunercept, a CD95L-selective inhibitor, in hospitalised patients with moderate-to-severe COVID-19: ASUNCTIS, a multicentre, randomised, open-label, controlled, phase 2 trial
errECLINICALMEDICINE
IF10
err2024-11-01
err0
errOAAI
errSeco, Maria Pilar Ruiz; Pardo, Jose Ramon Pano; Schoergenhofer, Christian; Dings, Christiane; Lehr, Thorsten; Herth, Felix; Krendyukov, Andriy; Straub, Carola; Kappler, Martin; Jilma, Bernd; Fricke, Harald; Pardo, Julian; de Miguel, Diego; Thiemann, Meinolf; Bergmann, Michael; Walczak, Henning; Hoeger, Thomas
err分享
err收藏
Burden of cardiovascular disease attributable to metabolic risks in 204 countries and territories from 1990 to 2021
errEUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
IF4.6
err2024-10-23
err0
PREAI
errChen, Huimin; Liu, Lu; Wang, Yi; Hong, Liqiong; Zhong, Wen; Lehr, Thorsten; Bragazzi, Nicola Luigi; Tang, Biao; Dai, Haijiang
err分享
err收藏
Redefining pandemic preparedness: Multidisciplinary insights from the CERP modelling workshop in infectious diseases, workshop report
errINFECTIOUS DISEASE MODELLING
IF2.5
err2024-06-01
err5
errOAAI
errNunes, Marta C.; Thommes, Edward; Froehlich, Holger; Flahault, Antoine; Arino, Julien; Baguelin, Marc; Biggerstaff, Matthew; Bizel-Bizellot, Gaston; Borchering, Rebecca; Cacciapaglia, Giacomo; Cauchemez, Simon; Barbier-Chebbah, Alex; Claussen, Carsten; Choirat, Christine; Cojocaru, Monica; Commaille-Chapus, Catherine; Hon, Chitin; Kong, Jude; Lambert, Nicolas; Lauer, Katharina B.; Lehr, Thorsten; Mahe, Cedric; Marechal, Vincent; Mebarki, Adel; Moghadas, Seyed; Niehus, Rene; Opatowski, Lulla; Parino, Francesco; Pruvost, Gery; Schuppert, Andreas; Thiebaut, Rodolphe; Thomas-Bachli, Andrea; Viboud, Cecile; Wu, Jianhong; Crepey, Pascal; Coudeville, Laurent
err分享
err收藏

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