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R

Rahul M. Kohli

University of Pennsylvania

44H指数
155论文数
8.2K被引数
收录论文 69
发表时间
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A theoretical and experimental framework enables low-coverage sequencing for accurate quantification of genome-wide cytosine modification levels一个理论实验框架实现了低覆盖度测序以精确量化全基因组范围内胞嘧啶修饰水平
errNAR Genomics and Bioinformatics
IF2.8
err2026-07-28
err0
errOAAI
errChristian E Loo; Johanna M Fowler; Heqiao Zhu; Christopher Krapp; Ruiyao Zhu; Marisa S Bartolomei; Wanding Zhou; Rahul M Kohli
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Inducible, split base editors for in vivo cancer functional genomics用于体内癌症功能基因组学的诱导型，分裂碱基编辑器
errNature Biotechnology
IF41.7
err2026-04-15
err0
errOAAI
errDiqiu Ren; Shangshang Wang; Keisuke Yamada; Yuqiao Liu; Robert Hapke; Aktan Alpsoy; Yugong Ho; Canjing Zhang; Yemin Lan; Shuo Zhang; Joseph P. Milazzo; Ruchi Lohia; Kiara N. Berríos; Yongjun Li; Evan W. Weber; Qin Li; Christopher R. Vakoc; Andy J. Minn; Rahul M. Kohli; Junwei Shi
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Unnatural Cytosine Analogs Potentiate a Customizable; Enzymatic Method for Integrated Epigenetic and Four-Base Genetic Sequencing非天然胞嘧啶类似物增强了可定制的酶法，用于整合表观遗传和四碱基遗传测序
errJournal of the American Chemical Society
IF15.6
err2026-03-11
err0
errOAAI
errChristian E. Loo; Jared B. Parker; Aleksia Barka; Ruiyao Zhu; Matthew R. Schnell; Rosella G. Cuomo; Heqiao Zhu; Laura Liu; Ashley Chen; Jasleen Gill; Wanding Zhou; Rahul M. Kohli
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A ternary-code DNA methylome atlas of mouse tissues小鼠组织的三进制编码DNA甲基组图谱
errGenome Biology
IF9.4
err2025-10-09
err0
errOAAI
errSol Moe Lee; David C. Goldberg; Cameron Cloud; Jared B. Parker; Christopher Krapp; Christian E. Loo; Elliot Kim; Ivan Zhao; Chengcheng Jin; Rishi Porecha; Marisa S. Bartolomei; Rahul M. Kohli; Wanding Zhou
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The bacterial stress response polymerase DinB tolerates sugar modifications and preferentially incorporates arabinosyl nucleotides细菌应激响应聚合酶DinB耐受糖基修饰并优先掺入阿拉伯糖核苷酸
errRSC Chem. Biol.
IF3.1
err2025-09-01
err0
errOAAI
errChristina M. Hurley; Jeffrey M. Kubiak; Michael B. Cory; Jared B. Parker; Christian E. Loo; Laura C. Wang; Rahul M. Kohli
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Scalable screening of ternary-code DNA methylation dynamics associated with human traits可扩展的三元编码DNA甲基化动态与人表型相关的筛选
errCell Genomics
IF9
err2025-07-03
err0
errOAAI
errDavid C. Goldberg; Cameron Cloud; Sol Moe Lee; Bret Barnes; Steven Gruber; Elliot Kim; Anita Pottekat; Maximillian S. Westphal; Luana McAuliffe; Elisa Majounie; Manesh Kalayil Manian; Qingdi Zhu; Christine Tran; Mark Hansen; Jelena Stojakovic; Jared B. Parker; Rahul M. Kohli; Rishi Porecha; Nicole Renke; Wanding Zhou
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The LexA-RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-05-16
err1
PREAI
errCory, Michael B.; Li, Allen; Hurley, Christina M.; Carman, Peter J.; Pumroy, Ruth A.; Hostetler, Zachary M.; Perez, Ryann M.; Venkatesh, Yarra; Li, Xinning; Gupta, Kushol; Petersson, E. James; Kohli, Rahul M.
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Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions
errDEVELOPMENTAL CELL
IF8.7
err2024-04-01
err2
PREAI
errPrasasya, Rexxi D.; Caldwell, Blake A.; Liu, Zhengfeng; Wu, Songze; Leu, N. Adrian; Fowler, Johanna M.; Cincotta, Steven A.; Laird, Diana J.; Kohli, Rahul M.; Bartolomei, Marisa S.
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Investigating the CRISPR-Cas12a mechanism to design hyper-efficient genome editors
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errGill, Jasleen; Ren, Diqiu; Berrios, Kiara; Barka, Aleksia; Evitt, Niklaus; Shi, Junwei; Kohli, Rahul
err分享
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Low-input and single-cell methods for Infinium DNA methylation BeadChips
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-02-26
err2
errOAAI
errLee, Sol Moe; Loo, Christian E.; Prasasya, Rexxi D.; Bartolomei, Marisa S.; Kohli, Rahul M.; Zhou, Wanding
err分享
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Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies
errNATURE COMMUNICATIONS
IF15.7
err2024-01-29
err5
errOAAI
errMedina-Munoz, Hugo C.; Kofman, Eric; Jagannatha, Pratibha; Boyle, Evan A.; Yu, Tao; Jones, Krysten L.; Mueller, Jasmine R.; Lykins, Grace D.; Doudna, Andrew T.; Park, Samuel S.; Blue, Steven M.; Ranzau, Brodie L.; Kohli, Rahul M.; Komor, Alexis C.; Yeo, Gene W.
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Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-01-23
err2
errOAAI
errBerrios, Kiara N.; Barka, Aleksia; Gill, Jasleen; Serrano, Juan C.; Bailer, Peter F.; Parker, Jared B.; Evitt, Niklaus H.; Gajula, Kiran S.; Shi, Junwei; Kohli, Rahul M.
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CRISPR tiling screen reveals cancer epigenetic Goldilocks' state
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2023-09-01
err0
errOAAI
errBarka, Aleksia; Kohli, Rahul M.; Shi, Junwei
err分享
err收藏
Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects联合单细胞分析可解决5mC和5hmC，并揭示其独特的基因调控作用
errNATURE BIOTECHNOLOGY
IF41.7
err2023-08-28
err11
PREAI
errFabyanic, Emily B.; Hu, Peng; Qiu, Qi; Berrios, Kiara N.; Connolly, Daniel R.; Wang, Tong; Flournoy, Jennifer; Zhou, Zhaolan; Kohli, Rahul M.; Wu, Hao
err分享
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Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma肌分化报告筛查显示nf-y是横纹肌肉瘤中PAX3-FOXO1的激活剂
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-08-28
err7
errOAAI
errSroka, Martyna W.; Skopelitis, Damianos; Vermunt, Marit W.; Preall, Jonathan B.; El Demerdash, Osama; de Almeida, Larissa M. N.; Chang, Kenneth; Utama, Raditya; Gryder, Berkley; Caligiuri, Giuseppina; Ren, Diqiu; Nalbant, Benan; Milazzo, Joseph P.; Tuveson, David A.; Dobin, Alexander; Hiebert, Scott W.; Stengel, Kristy R.; Mantovani, Roberto; Khan, Javed; Kohli, Rahul M.; Shi, Junwei; Blobel, Gerd A.; Vakoc, Christopher R.
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Revealing Drivers for Carboxy-S-adenosyl-l-methionine Use by Neomorphic Variants of a DNA Methyltransferase
errACS CHEMICAL BIOLOGY
IF3.8
err2023-06-28
err1
errOAAI
errLoo, Christian E.; Hix, Mark A.; Wang, Tong; Cisneros, G. Andres; Kohli, Rahul M.
err分享
err收藏
Direct enzymatic sequencing of 5-methylcytosine at single-base resolution单碱基分辨率下5-甲基胞嘧啶的直接酶促测序
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-06-15
err23
PREAI
errWang, Tong; Fowler, Johanna M.; Liu, Laura; Loo, Christian E.; Luo, Meiqi; Schutsky, Emily K.; Berrios, Kiara N.; DeNizio, Jamie E.; Dvorak, Ashley; Downey, Nick; Montermoso, Saira; Pingul, Bianca Y.; Nasrallah, MacLean; Gosal, Walraj S.; Wu, Hao; Kohli, Rahul M.
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Efficient engineering of human and mouse primary cells using peptide-assisted genome editing
errNATURE BIOTECHNOLOGY
IF41.7
err2023-04-24
err35
PREAI
errZhang, Zhen; Baxter, Amy E. E.; Ren, Diqiu; Qin, Kunhua; Chen, Zeyu; Collins, Sierra M. M.; Huang, Hua; Komar, Chad A. A.; Bailer, Peter F. F.; Parker, Jared B. B.; Blobel, Gerd A. A.; Kohli, Rahul M. M.; Wherry, E. John; Berger, Shelley L. L.; Shi, Junwei
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Mpox Evolution: Has the Current Outbreak Revealed a Pox on U?
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2022-12-09
err2
errOAAI
errKohli, Rahul M.; Isaacs, Stuart N.
err分享
err收藏
Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A针对基因组突变体APOBEC3A的有效和特异性抑制剂的结构指导设计
errACS CHEMICAL BIOLOGY
IF3.8
err2022-12-08
err17
errOAAI
errSerrano, Juan C.; von Trentini, Dora; Berrios, Kiara N.; Barka, Aleksia; Dmochowski, Ivan J.; Kohli, Rahul M.
err分享
err收藏

研究方向

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合作学者
合作期刊
C
Carl H. June
H 指数: 177 · 论文数: 1.4K
J
Joseph R. Ecker
H 指数: 168 · 论文数: 537
Chuan He 封面图
Chuan He (Chuan He)
H 指数: 161 · 论文数: 982
C
Christopher T. Walsh
H 指数: 144 · 论文数: 852
E
E. John Wherry
H 指数: 142 · 论文数: 640
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