未登录 Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression 骨髓增生异常肿瘤中环状RNA表达景观：与突变特征和疾病进展的关联 Wedge, Eileen; Tulstrup, Morten; Todisco, Gabriele; Moura, Pedro; Come, Christophe; Hansen, Jakob Werner; Jespersen, Jakob Schmidt; Schlotmann, Balthasar; Creignou, Maria; Dahl, Mette; Schollkopf, Claudia; Raaschou-Jensen, Klas; Wennerberg, Krister; Porse, Bo; Weischenfeldt, Joachim; Hellstrom-Lindberg, Eva; Kristensen, Lasse Sommer; Gronbaek, Kirsten 分享 收藏
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DRUG-RESPONSE ANALYSIS AND SINGLE NUCLEUS RNA SEQUENCING ON PATIENT-DERIVED NEUROSPHERES TO REVEAL DRUG RESPONSE AND RESISTANCE MECHANISMS IN GLIOBLASTOMA 对患者来源的神经球进行药物反应分析和单核RNA测序，以揭示胶质母细胞瘤的药物反应和耐药机制 Lu, M. J. S.; Hendriksen, J. D.; Ariey-Bonnet, J.; Anand, A.; Michaelsen, S. R.; Gonzalez, F. G. R.; Locallo, A.; Azam, A.; Skjoth-Rasmussen, J.; Hamerlik, P.; Noroxe, D. S.; Hasselbalch, B.; Vik-Mo, E.; Kristensen, B. W.; Urup, T.; Lassen, U.; Poulsen, H. S.; Wennerberg, K.; Weischenfeldt, J. 分享 收藏
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Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones 单细胞转录组鉴定针对癌症克隆的选择性共抑制的患者定制疗法 Ianevski, Aleksandr; Nader, Kristen; Driva, Kyriaki; Senkowski, Wojciech; Bulanova, Daria; Moyano-Galceran, Lidia; Ruokoranta, Tanja; Kuusanmaki, Heikki; Ikonen, Nemo; Sergeev, Philipp; Vaha-Koskela, Markus; Giri, Anil K.; Vaharautio, Anna; Kontro, Mika; Porkka, Kimmo; Pitkanen, Esa; Heckman, Caroline A.; Wennerberg, Krister; Aittokallio, Tero 分享 收藏
Establishment and evaluation of radioresistant models from patient derived tissue Cold, S.; Alfsen, M. Zeiler; Thaysen, M.; Ariey-Bonnet, J.; Boge, R. Norgaard; Papin, E.; Nielsen, N.; Michler, I.; Kristensen, L. Kellemann; Wick, M.; Kjaer, A.; Wennerberg, K.; Nielsen, C. Haagen; Gnosa, S. 分享 收藏
GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma Avenel, Ines C. N.; Ewald, Jesper D.; Ariey-Bonnet, Jeremy; Kristensen, Ida H.; Petterson, Stine A.; Thesbjerg, Martin N.; Burton, Mark; Thomassen, Mads; Wennerberg, Krister; Michaelsen, Signe R.; Kristensen, Bjarne W. 分享 收藏
A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells 对RB1-deficient癌细胞中复制干扰疗法的酪蛋白激酶2的合成致死依赖性 Bulanova, Daria; Akimov, Yevhen; Senkowski, Wojciech; Oikkonen, Jaana; Gall-Mas, Laura; Timonen, Sanna; Elmadani, Manar; Hynninen, Johanna; Hautaniemi, Sampsa; Aittokallio, Tero; Wennerberg, Krister 分享 收藏
Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia 综合药物分析和CRISPR筛选确定BCR:: 慢性粒细胞白血病的ABL1-independent脆弱性 Awad, Shady Adnan; Dufva, Olli; Klievink, Jay; Karjalainen, Ella; Ianevski, Aleksandr; Pietarinen, Paavo; Kim, Daehong; Potdar, Swapnil; Wolf, Maija; Lotfi, Kourosh; Aittokallio, Tero; Wennerberg, Krister; Porkka, Kimmo; Mustjoki, Satu 分享 收藏
Interactive analysis of drug testing data for functional precision oncology with Breeze 2.0 Potdar, Swapnil; Ianevski, Filipp; Ianevski, Aleksandr; Tanoli, Ziaurrehman; Wennerberg, Krister; Seashore-Ludlow, Brinton; Kallioniemi, Olli; Ostling, Paivi; Aittokallio, Tero; Saarela, Jani 分享 收藏
Application of high-grade serous ovarian cancer organoids in functional precision medicine Senkowski, Wojciech; Gall-Mas, Laura; Falco, Matias M.; Li, Yilin; Lavikka, Kari; Crispino, Aura; Oikkonen, Jaana; Bulanova, Daria; Chen, Yan-Jun; Doncel, Elena M.; Vossgrone, Karolin; Erkan, Erdogan P.; Dai, Jun; Lundgren, Anastasia; Huvila, Jutta; Huhtinen, Kaisa; Hynninen, Johanna; Hautaniemi, Sampsa; Vaharautio, Anna; Wennerberg, Krister 分享 收藏
Standardized assays to monitor drug sensitivity in hematologic cancers Ayuda-Duran, Pilar; Hermansen, Johanne U.; Giliberto, Mariaserena; Yin, Yanping; Hanes, Robert; Gordon, Sandra; Kuusanmaki, Heikki; Brodersen, Andrea M.; Andersen, Aram N.; Tasken, Kjetil; Wennerberg, Krister; Enserink, Jorrit M.; Skanland, Sigrid S. 分享 收藏
Robust scoring of selective drug responses for patient-tailored therapy selection 用于患者定制治疗选择的选择性药物反应的稳健评分 Chen, Yingjia; He, Liye; Ianevski, Aleksandr; Ayuda-Duran, Pilar; Potdar, Swapnil; Saarela, Jani; Miettinen, Juho J.; Kytola, Sari; Miettinen, Susanna; Manninen, Mikko; Heckman, Caroline A.; Enserink, Jorrit M.; Wennerberg, Krister; Aittokallio, Tero 分享 收藏
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells PP2A-based三重打击疗法克服了脑癌细胞的线粒体凋亡抗性 Denisova, Oxana V.; Merisaari, Joni; Huhtaniemi, Riikka; Qiao, Xi; Yetukuri, Laxman; Jumppanen, Mikael; Kaur, Amanpreet; Paakkonen, Mirva; von Schantz-Fant, Carina; Ohlmeyer, Michael; Wennerberg, Krister; Kauko, Otto; Koch, Raphael; Aittokallio, Tero; Taipale, Mikko; Westermarck, Jukka 分享 收藏
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A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids Senkowski, Wojciech; Gall-Mas, Laura; Falco, Matias Marin; Li, Yilin; Lavikka, Kari; Kriegbaum, Mette C.; Oikkonen, Jaana; Bulanova, Daria; Pietras, Elin J.; Vossgrone, Karolin; Chen, Yan-Jun; Erkan, Erdogan Pekcan; Dai, Jun; Lundgren, Anastasia; Hog, Mia Kristine Gronning; Larsen, Ida Marie; Lamminen, Tarja; Kaipio, Katja; Huvila, Jutta; Virtanen, Anni; Engelholm, Lars; Christiansen, Pernille; Santoni-Rugiu, Eric; Huhtinen, Kaisa; Carpen, Olli; Hynninen, Johanna; Hautaniemi, Sampsa; Vaharautio, Anna; Wennerberg, Krister 分享 收藏
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data Breeze 2.0: 用于可视化分析和比较药物反应数据的交互式网络工具 Potdar, Swapnil; Ianevski, Filipp; Ianevski, Aleksandr; Tanoli, Ziaurrehman; Wennerberg, Krister; Seashore-Ludlow, Brinton; Kallioniemi, Olli; Ostling, Paeivi; Aittokallio, Tero; Saarela, Jani 分享 收藏
Determination of KRAS- and ERK-regulated phosphoproteomes in KRAS-mutant cancers Klomp, Jennifer E.; Klomp, Jeff A.; Diehl, Nathaniel J.; Edwards, Cole A.; Drizyte-Miller, Kristina; Hibshman, Priya S.; Yang, Runying; Morales, Alexis J.; Taylor, Khalilah E.; Pierobon, Mariaelena; Petricoin, Emanuel F., III; Jared, Johnson L.; Huntsman, Emily M.; Yaron, Tomer M.; Vaha-Koskela, Markus; Herring, Laura E.; Prevatte, Alex W.; Barker, Natalie K.; Graves, Lee M.; Krister, Wennerberg; Cantley, Lewis C.; Christensen, James G.; Cox, Adrienne D.; Der, Channing J.; Stalnecker, Clint A. 分享 收藏
A platform utilizing high-grade serous ovarian cancer organoids for prospective patient stratification in functional precision medicine Senkowski, Wojciech; Gall-Mas, Laura; Falco, Matias M.; Li, Yilin; Lavikka, Kari; Kriegbaum, Mette C.; Oikkonen, Jaana; Bulanova, Daria; Pietras, Elin J.; Vossgrone, Karolin; Chen, Yan-Jun; Erkan, Erdogan P.; Hog, Mia K.; Larsen, Ida M.; Lamminen, Tarja; Kaipio, Katja; Huvila, Jutta; Virtanen, Anni; Engelholm, Lars H.; Christiansen, Pernille; Rugiu, Eric Santoni; Huhtinen, Kaisa; Carpen, Olli; Hynninen, Johanna; Hautaniemi, Sampsa; Vaharautio, Anna; Wennerberg, Krister 分享 收藏
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