未登录 Ectopic NSD2 Remodels H3K36me2 and DNA Methylation to Promote Oncogenic Gene Expression in Multiple Myeloma 异位NSD2重塑H3K36me2和DNA甲基化以促进多发性骨髓瘤中致癌基因的表达 Chavez, Robert M.; Powell, Doris R.; Lakhani, Kiran; Attelah, John; Flynt, Erin; Connolly, Terry; Hamilton, Mark; Mulligan, George; Auclair, Daniel; Keats, Jonathan; Vertino, Paula M.; Boise, Lawrence H.; Lonial, Sagar; Conneely, Karen N.; Barwick, Benjamin G. 分享 收藏
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes 多发性骨髓瘤的综合分子谱分析可确定精细的拷贝数和表达亚型 Skerget, Sheri; Penaherrera, Daniel; Chari, Ajai; Jagannath, Sundar; Siegel, David S.; Vij, Ravi; Orloff, Gregory; Jakubowiak, Andrzej; Niesvizky, Ruben; Liles, Darla; Berdeja, Jesus; Levy, Moshe; Wolf, Jeffrey; Usmani, Saad Z.; Christofferson, Austin W.; Nasser, Sara; Aldrich, Jessica L.; Legendre, Christophe; Benard, Brooks; Miller, Chase; Turner, Bryce; Kurdoglu, Ahmet; Washington, Megan; Yellapantula, Venkata; Adkins, Jonathan R.; Cuyugan, Lori; Boateng, Martin; Helland, Adrienne; Kyman, Shari; McDonald, Jackie; Reiman, Rebecca; Stephenson, Kristi; Tassone, Erica; Blanski, Alex; Livermore, Brianne; Kirchhoff, Meghan; Rohrer, Daniel C.; D'Agostino, Mattia; Gamella, Manuela; Collison, Kimberly; Stumph, Jennifer; Kidd, Pam; Donnelly, Andrea; Zaugg, Barbara; Toone, Maureen; McBride, Kyle; DeRome, Mary; Rogers, Jennifer; Craig, David; Liang, Winnie S.; Gutierrez, Norma C.; Jewell, Scott D.; Carpten, John; Anderson, Kenneth C.; Cho, Hearn Jay; Auclair, Daniel; Lonial, Sagar; Keats, Jonathan J. 分享 收藏
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Multiplexed flow cytometry based immunophenotyping paired with functional ex vivo (MFLEX) drug profiling informs potential efficacy of therapeutic agents in acute myeloid leukemia Shah, Reecha; Wander, Heba; Hsueh, Michelle; Floren, Muskan; Liu, Wei; Cheung, Patricia; Andersen, Courtney; White, Michael; Kingston, Nathan; Gutierrez, Pablo Morentin; Drew, Lisa; Fabbri, Giulia; Bibikova, Elena; Auclair, Daniel 分享 收藏
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias Simoes, Ricardo de Matos; Shirasaki, Ryosuke; Downey-Kopyscinski, Sondra L.; Matthews, Geoffrey M.; Barwick, Benjamin G.; Gupta, Vikas A.; Dupere-Richer, Daphne; Yamano, Shizuka; Hu, Yiguo; Sheffer, Michal; Dhimolea, Eugen; Dashevsky, Olga; Gandolfi, Sara; Ishiguro, Kazuya; Meyers, Robin M.; Bryan, Jordan G.; Dharia, Neekesh V.; Hengeveld, Paul J.; Bruggenthies, Johanna B.; Tang, Huihui; Aguirre, Andrew J.; Sievers, Quinlan L.; Ebert, Benjamin L.; Glassner, Brian J.; Ott, Christopher J.; Bradner, James E.; Kwiatkowski, Nicholas P.; Auclair, Daniel; Levy, Joan; Keats, Jonathan J.; Groen, Richard W. J.; Gray, Nathanael S.; Culhane, Aedin C.; McFarland, James M.; Dempster, Joshua M.; Licht, Jonathan D.; Boise, Lawrence H.; Hahn, William C.; Vazquez, Francisca; Tsherniak, Aviad; Mitsiades, Constantine S. 分享 收藏
Altered immune response to vaccination in patients with plasma cell premalignancy Konishi, Yoshinobu; Sklavenitis-Pistofidis, Romanos; Aranha, Michelle P.; Wu, Ting; Yue, Hong; Lightbody, Elizabeth D.; Rahmat, Mahshid; Timonian, Michael; Varmeh, Shohreh; Heilpern-Mallory, Daniel; Agius, Michael P.; Su, Nang K.; Perry, Jacqueline; Horowitz, Erica; Davis, Maya I.; Justis, Anna V.; Nowak, Radoslaw P.; Hamilton, Mark; Auclair, Daniel; Marinac, Catherine R.; Fischer, Eric S.; Getz, Gad; Ghobrial, Irene M. 分享 收藏
Utility of ctDNA-based targeted methylation MRD assay for hematological malignancies Munugalavadla, Veerendra; de Jesus, Gary; Markovets, Aleksandra; Liu, Qinwen; Venn, Oliver; White, Rafael; Fabbri, Giulia; Labrousse, Paul; Stetson, Dan; Dougherty, Brian; Hodgson, Darren; Walker, Jill; Younes, Anas; Auclair, Daniel 分享 收藏
Extreme body mass index and survival in newly diagnosed multiple myeloma patients Shah, Urvi A. A.; Whiting, Karissa; Devlin, Sean; Ershler, Rachel; Kanapuru, Bindu; Lee, David J. J.; Tahri, Sabrin; Gwise, Thomas; Rustad, Even H. H.; Mailankody, Sham; Lesokhin, Alexander M. M.; Kazandjian, Dickran; Maura, Francesco; Auclair, Daniel; Birmann, Brenda M. M.; Usmani, Saad Z. Z.; Gormley, Nicole; Marinac, Catherine R. R.; Landgren, Ola 分享 收藏
MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology Minimumm-seq: 循环肿瘤细胞的基因组测序，用于多发性骨髓瘤病理学的微创分子表征 Dutta, Ankit K.; Alberge, Jean-Baptiste; Lightbody, Elizabeth D.; Boehner, Cody J.; Dunford, Andrew; Sklavenitis-Pistofidis, Romanos; Mouhieddine, Tarek H.; Cowan, Annie N.; Su, Nang Kham; Horowitz, Erica M.; Barr, Hadley; Hevenor, Laura; Beckwith, Jenna B.; Perry, Jacqueline; Cao, Amanda; Lin, Ziao; Kuhr, Frank K.; Del Mastro, Richard G.; Nadeem, Omar; Greipp, Patricia T.; Stewart, Chip; Auclair, Daniel; Getz, Gad; Ghobrial, Irene M. 分享 收藏
Perspectives on the Risk-Stratified Treatment of Multiple Myeloma Davies, Faith E.; Pawlyn, Charlotte; Usmani, Saad Z.; San-Miguel, Jesus F.; Einsele, Hermann; Boyle, Eileen M.; Corre, Jill; Auclair, Daniel; Cho, Hearn Jay; Lonial, Sagar; Sonneveld, Pieter; Stewart, A. Keith; Bergsagel, P. Leif; Kaiser, Martin F.; Weisel, Katja; Keats, Jonathan J.; Mikhael, Joseph R.; Morgan, Kathryn E.; Ghobrial, Irene M.; Orlowski, Robert Z.; Landgren, C. Ola; Gay, Francesca; Caers, Joseph; Chng, Wee Joo; Chari, Ajai; Walker, Brian A.; Kumar, Shaji K.; Costa, Luciano J.; Anderson, Kenneth C.; Morgan, Gareth J. 分享 收藏
Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer Ghamlouch, Hussein; Boyle, Eileen M.; Blaney, Patrick; Wang, Yubao; Choi, Jinyoung; Williams, Louis; Bauer, Michael; Auclair, Daniel; Bruno, Benedetto; Walker, Brian A.; Davies, Faith E.; Morgan, Gareth J. 分享 收藏
Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length 使用获得性遗传特征，克隆性造血和端粒长度改善老年多发性骨髓瘤患者的预后分配 Boyle, Eileen M.; Williams, Louis; Blaney, Patrick; Ashby, Cody; Bauer, Michael; Walker, Brian A.; Ghamlouch, Hussein; Choi, Jinyoung; Perrial, Emeline; Wang, Yubao; Caro, Jessica; Stoeckle, James H.; Arbini, Arnaldo; Kaminetzky, David; Braunstein, Marc; Bruno, Benedetto; Razzo, Beatrice; Diamond, Benjamin; Maclachlan, Kylee; Maura, Francesco; Landgren, Ola; Litke, Rachel; Fegan, Christopher D.; Keats, Johnathan; Auclair, Daniel; Davies, Faith E.; Morgan, Gareth J. 分享 收藏
Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins 功能基因组学鉴定介导对不同类别的癌蛋白异双功能降解物抗性的不同和重叠基因 Shirasaki, Ryosuke; Matthews, Geoffrey M.; Gandolfi, Sara; Simoes, Ricardo de Matos; Buckley, Dennis L.; Vora, Joseline Raja; Sievers, Quinlan L.; Bruggenthies, Johanna B.; Dashevsky, Olga; Poarch, Haley; Tang, Huihui; Bariteau, Megan A.; Sheffer, Michal; Hu, Yiguo; Downey-Kopyscinski, Sondra L.; Hengeveld, Paul J.; Glassner, Brian J.; Dhimolea, Eugen; Ott, Christopher J.; Zhang, Tinghu; Kwiatkowski, Nicholas P.; Laubach, Jacob P.; Schlossman, Robert L.; Richardson, Paul G.; Culhane, Aedin C.; Groen, Richard W. J.; Fischer, Eric S.; Vazquez, Francisca; Tsherniak, Aviad; Hahn, William C.; Levy, Joan; Auclair, Daniel; Licht, Jonathan D.; Keats, Jonathan J.; Boise, Lawrence H.; Ebert, Benjamin L.; Bradner, James E.; Gray, Nathanael S.; Mitsiades, Constantine S. 分享 收藏
Revealing the Impact of Structural Variants in Multiple Myeloma 揭示结构变异对多发性骨髓瘤的影响 Rustad, Even H.; Yellapantula, Venkata D.; Glodzik, Dominik; Maclachlan, Kylee H.; Diamond, Benjamin; Boyle, Eileen M.; Ashby, Cody; Blaney, Patrick; Gundem, Gunes; Hultcrantz, Malin; Leongamornlert, Daniel; Angelopoulos, Nicos; Agnelli, Luca; Auclair, Daniel; Zhang, Yanming; Dogan, Ahmet; Bolli, Niccolo; Papaemmanuil, Elli; Anderson, Kenneth C.; Moreau, Philippe; Avet-Loiseau, Herve; Munshi, Nikhil C.; Keats, Jonathan J.; Campbell, Peter J.; Morgan, Gareth J.; Landgren, Ola; Maura, Francesco 分享 收藏
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant Mouhieddine, Tarek H.; Sperling, Adam S.; Redd, Robert; Park, Jihye; Leventhal, Matthew; Gibson, Christopher J.; Manier, Salomon; Nassar, Amin H.; Capelletti, Marzia; Huynh, Daisy; Bustoros, Mark; Sklavenitis-Pistofidis, Romanos; Tahri, Sabrin; Hornburg, Kalvis; Dumke, Henry; Itani, Muhieddine M.; Boehner, Cody J.; Liu, Chia-Jen; AlDubayan, Saud H.; Reardon, Brendan; Van Allen, Eliezer M.; Keats, Jonathan J.; Stewart, Chip; Mehr, Shaadi; Auclair, Daniel; Schlossman, Robert L.; Munshi, Nikhil C.; Anderson, Kenneth C.; Steensma, David P.; Laubach, Jacob P.; Richardson, Paul G.; Ritz, Jerome; Ebert, Benjamin L.; Soiffer, Robert J.; Trippa, Lorenzo; Getz, Gad; Neuberg, Donna S.; Ghobrial, Irene M. 分享 收藏
A meta-analysis of genome-wide association study and eQTL analysis of multiple myeloma among African Americans Du, Zhaohui; Weinhold, Niels; Song, Gregory Chi; Rand, Kristen A.; Van den Berg, David J.; Hwang, Amie E.; Sheng, Xin; Hom, Victor; Ailawadhi, Sikander; Nooka, Ajay K.; Singhal, Seema; Pawlish, Karen; Peters, Edward; Bock, Cathryn; Mohrbacher, Ann; Stram, Alexander; Berndt, Sonja, I; Blot, William J.; Casey, Graham; Stevens, Victoria L.; Kittles, Rick; Goodman, Phyllis J.; Diver, W. Ryan; Hennis, Anselm; Nemesure, Barbara; Klein, Eric A.; Rybicki, Benjamin A.; Stanford, Janet L.; Witte, John S.; Signorello, Lisa; John, Esther M.; Bernstein, Leslie; Stroup, Antoinette; Stephens, Owen W.; Zangari, Maurizio; Van Rhee, Frits; Olshan, Andrew; Zheng, Wei; Hu, Jennifer J.; Ziegler, Regina; Nyante, Sarah J.; Ingles, Sue Ann; Press, Michael; Carpten, John David; Chanock, Stephen; Mehta, Jayesh; Colditz, Graham A.; Wolf, Jeffrey; Martin, Thomas G.; Tomasson, Michael; Fiala, Mark A.; Terebelo, Howard; Janakiraman, Nalini; Kolonel, Laurence; Anderson, Kenneth C.; Le Marchand, Loic; Auclair, Daniel; Chiu, Brian C-H; Ziv, Elad; Stram, Daniel; Vij, Ravi; Bernal-Mizrachi, Leon; Morgan, Gareth J.; Zonder, Jeffrey A.; Huff, Carol Ann; Lonial, Sagar; Orlowski, Robert Z.; Conti, David, V; Haiman, Christopher A. 分享 收藏
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease Mason, Mike J.; Schinke, Carolina; Eng, Christine L. P.; Towfic, Fadi; Gruber, Fred; Dervan, Andrew; White, Brian S.; Pratapa, Aditya; Guan, Yuanfang; Chen, Hongjie; Cui, Yi; Li, Bailiang; Yu, Thomas; Chaibub Neto, Elias; Mavrommatis, Konstantinos; Ortiz, Maria; Lyzogubov, Valeriy; Bisht, Kamlesh; Dai, Hongyue Y.; Schmitz, Frank; Flynt, Erin; Rozelle, Dan; Danziger, Samuel A.; Ratushny, Alexander; Dalton, William S.; Goldschmidt, Hartmut; Avet-Loiseau, Herve; Samur, Mehmet; Hayete, Boris; Sonneveld, Pieter; Shain, Kenneth H.; Munshi, Nikhil; Auclair, Daniel; Hose, Dirk; Morgan, Gareth; Trotter, Matthew; Bassett, Douglas; Goke, Jonathan; Walker, Brian A.; Thakurta, Anjan; Guinney, Justin 分享 收藏
A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry Du, Zhaohui; Weinhold, Niels; Song, Gregory Chi; Rand, Kristin A.; Van Den Berg, David J.; Hwang, Amie E.; Sheng, Xin; Hom, Victor; Ailawadhi, Sikander; Nooka, Ajay K.; Singhal, Seema; Pawlish, Karen; Peters, Edward S.; Bock, Cathryn; Mohrbacher, Ann; Stram, Alexander; Berndt, Sonja, I; Blot, William J.; Casey, Graham; Stevens, Victoria L.; Kittles, Rick; Goodman, Phyllis J.; Diver, W. Ryan; Hennis, Anselm; Nemesure, Barbara; Klein, Eric A.; Rybicki, Benjamin A.; Stanford, Janet L.; Witte, John S.; Signorello, Lisa; John, Esther M.; Bernstein, Leslie; Stroup, Antoinette M.; Stephens, Owen W.; Zangari, Maurizio; Van Rhee, Frits; Olshan, Andrew; Zheng, Wei; Hu, Jennifer J.; Ziegler, Regina; Nyante, Sarah J.; Ingles, Sue Ann; Press, Michael F.; Carpten, John David; Chanock, Stephen J.; Mehta, Jayesh; Colditz, Graham A.; Wolf, Jeffrey; Martin, Thomas G.; Tomasson, Michael; Fiala, Mark A.; Terebelo, Howard; Janakiraman, Nalini; Kolonel, Laurence; Anderson, Kenneth C.; Le Marchand, Loic; Auclair, Daniel; Chiu, Brian C-H; Ziv, Elad; Stram, Daniel; Vij, Ravi; Bernal-Mizrachi, Leon; Morgan, Gareth J.; Zonder, Jeffrey A.; Huff, Carol Ann; Lonial, Sagar; Orlowski, Robert Z.; Conti, David, V; Haiman, Christopher A.; Cozen, Wendy 分享 收藏
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Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma Mikulasova, Aneta; Ashby, Cody; Tytarenko, Ruslana G.; Qu, Pingping; Rosenthal, Adam; Dent, Judith A.; Ryan, Katie R.; Bauer, Michael A.; Wardell, Christopher P.; Hoering, Antje; Mavrommatis, Konstantinos; Trotter, Matthew; Deshpande, Shayu; Yaccoby, Shmuel; Tian, Erming; Keats, Jonathan; Auclair, Daniel; Jackson, Graham H.; Davies, Faith E.; Thakurta, Anjan; Morgan, Gareth J.; Walker, Brian A. 分享 收藏
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