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P

Patty T. Wai

the francis crick institute
H指数:15
被引数:1,191

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SF3B1 hotspot mutations confer sensitivity to PARP inhibition through a defective replication stress response
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Bland, Philip; Saville, Harry; Wai, Patty T.; Curnow, Lucinda; Nieminuszczy, Jadwiga; Ravindran, Nivedita; Barker, Holly E.; Wright, James; Yu, Lu; Mavrommati, Ioanna; Peck, Barrie; Gazinska, Patrycja; Pemberton, Helen N.; Gulati, Aditi; Guppy, Naomi; Roxanis, Ioannis; Pratt, Guy; Oldreive, Ceri; Stankovic, Tatjana; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah E.; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti S.; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Natrajan, Rachael
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response
NATURE GENETICS
IF31.8
2023-07-3118
OAAI
Bland, Philip; Saville, Harry; Wai, Patty T.; Curnow, Lucinda; Muirhead, Gareth; Nieminuszczy, Jadwiga; Ravindran, Nivedita; John, Marie Beatrix; Hedayat, Somaieh; Barker, Holly E.; Wright, James; Yu, Lu; Mavrommati, Ioanna; Read, Abigail; Peck, Barrie; Allen, Mark; Gazinska, Patrycja; Pemberton, Helen N.; Gulati, Aditi; Nash, Sarah; Noor, Farzana; Guppy, Naomi; Roxanis, Ioannis; Pratt, Guy; Oldreive, Ceri; Stankovic, Tatjana; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah E.; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti S.; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Natrajan, Rachael
Mutations in the RNA Splicing Factor SF3B1 drive endocrine therapy resistance and confer a targetable replication stress response defect through PARP inhibition
CANCER RESEARCH
IF16.6
2023-03-010
PRE
Bland, Phil; Saville, Harry; Read, Abigail; Wai, Patty; Muirhead, Gareth; Curnow, Lucinda; Nieminuszczy, Jadwiga; Ravindran, Nivedita; John, Marie; Hedayat, Somaieh; Barker, Holly; Wright, James; Yu, Lu; Mavrommati, Ioanna; Peck, Barrie; Allen, Mark; Gazinska, Patrycja; Pemberton, Helen; Gulati, Aditi; Nash, Sarah; Noor, Farzana; Guppy, Naomi; Roxanis, Ioannis; Barlow, Samantha; Kalirai, Helen; Coupland, Sarah; Broderick, Ronan; Alsafadi, Samar; Houy, Alexandre; Stern, Marc-Henri; Pettit, Stephen; Choudhary, Jyoti; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher; Natrajan, Rachael
Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts
GASTROENTEROLOGY
IF25.1
2021-10-0183
OA
Bortolomeazzi, Michele; Keddar, Mohamed Reda; Montorsi, Lucia; Acha-Sagredo, Amelia; Benedetti, Lorena; Temelkovski, Damjan; Choi, Subin; Petrov, Nedyalko; Todd, Katrina; Wai, Patty; Kohl, Johannes; Denner, Tamara; Nye, Emma; Goldstone, Robert; Ward, Sophia; Wilson, A. Gareth; Al Bakir, Maise; Swanton, Charles; John, Susan; Miles, James; Larijani, Banafshe; Kunene, Victoria; Fontana, Elisa; Arkenau, Hendrik-Tobias; Parker, J. Peter; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Spencer, Jo; Ciccarelli, D. Francesca
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer
CANCER RESEARCH
IF16.6
2021-02-1510
OA
Peck, Barrie; Bland, Philip; Mavrommati, Ioanna; Muirhead, Gareth; Cottom, Hannah; Wai, Patty T.; Maguire, Sarah L.; Barker, Holly E.; Morrison, Eamonn; Kriplani, Divya; Yu, Lu; Gibson, Amy; Falgari, Giulia; Brennan, Keith; Farnie, Gillian; Buus, Richard; Marlow, Rebecca; Novo, Daniela; Knight, Eleanor; Guppy, Naomi; Kolarevic, Daniela; Susnjar, Snezana; Milijic, Natasa Medic; Naidoo, Kalnisha; Gazinska, Patrycja; Roxanis, Ioannis; Pancholi, Sunil; Martin, Lesley-Ann; Holgersen, Erle M.; Cheang, Maggie C. U.; Noor, Farzana; Postel-Vinay, Sophie; Quinn, Gerard; McDade, Simon; Krasny, Lukas; Huang, Paul; Daley, Frances; Wallberg, Fredrik; Choudhary, Jyoti S.; Haider, Syed; Tutt, Andrew N.; Natrajan, Rachael
Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2018-01-0160
OA
Naidoo, Kalnisha; Wai, Patty T.; Maguire, Sarah L.; Daley, Frances; Haider, Syed; Kriplani, Divya; Campbell, James; Mirza, Hasan; Grigoriadis, Anita; Tutt, Andrew; Moseley, Paul M.; Abdel-Fatah, Tarek M. A.; Chan, Stephen Y. T.; Madhusudan, Srinivasan; Rhaka, Emad A.; Ellis, Ian O.; Lord, Christopher J.; Yuan, Yinyin; Green, Andrew R.; Natrajan, Rachael
Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

HER2基因异质性扩增乳腺癌的肿瘤内遗传异质性和替代驱动基因改变

GENOME BIOLOGY
IF9.4
2015-05-22118
OAAI
Ng, Charlotte K. Y.; Martelotto, Luciano G.; Gauthier, Arnaud; Wen, Huei-Chi; Piscuoglio, Salvatore; Lim, Raymond S.; Cowell, Catherine F.; Wilkerson, Paul M.; Wai, Patty; Rodrigues, Daniel N.; Arnould, Laurent; Geyer, Felipe C.; Bromberg, Silvio E.; Lacroix-Triki, Magali; Penault-Llorca, Frederique; Giard, Sylvia; Sastre-Garau, Xavier; Natrajan, Rachael; Norton, Larry; Cottu, Paul H.; Weigelt, Britta; Vincent-Salomon, Anne; Reis-Filho, Jorge S.
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast
JOURNAL OF PATHOLOGY
IF5.2
2014-02-0582
OAAI
Natrajan, Rachael; Wilkerson, Paul M.; Marchio, Caterina; Piscuoglio, Salvatore; Ng, Charlotte K. Y.; Wai, Patty; Lambros, Maryou B.; Samartzis, Eleftherios P.; Dedes, Konstantin J.; Frankum, Jessica; Bajrami, Ilirjana; Kopec, Alicja; Mackay, Alan; A'hern, Roger; Fenwick, Kerry; Kozarewa, Iwanka; Hakas, Jarle; Mitsopoulos, Costas; Hardisson, David; Lord, Christopher J.; Kumar-Sinha, Chandan; Ashworth, Alan; Weigelt, Britta; Sapino, Anna; Chinnaiyan, Arul M.; Maher, Christopher A.; Reis-Filho, Jorge S.
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

BRCA1突变型雌激素受体阴性和阳性乳腺癌的全基因组大规模平行测序分析

JOURNAL OF PATHOLOGY
IF5.2
2012-02-2351
OAAI
Natrajan, Rachael; Mackay, Alan; Lambros, Maryou B.; Weigelt, Britta; Wilkerson, Paul M.; Manie, Elodie; Grigoriadis, Anita; A'Hern, Roger; van der Groep, Petra; Kozarewa, Iwanka; Popova, Tatiana; Mariani, Odette; Turajlic, Samra; Furney, Simon J.; Marais, Richard; Rodruigues, Daniel-Nava; Flora, Adriana C.; Wai, Patty; Pawar, Vidya; McDade, Simon; Carroll, Jason; Stoppa-Lyonnet, Dominique; Green, Andrew R.; Ellis, Ian O.; Swanton, Charles; van Diest, Paul; Delattre, Olivier; Lord, Christopher J.; Foulkes, William D.; Vincent-Salomon, Anne; Ashworth, Alan; Stern, Marc Henri; Reis-Filho, Jorge S.

研究方向

暂未获取到该数据
R
Rachael Natrajan
H 指数:66论文数:389被引数:1.5万
S
Sarah Maguire
H 指数:17论文数:108被引数:1,402
B
Barrie Peck
H 指数:21论文数:119被引数:5,210
C
Christopher J. Lord
H 指数:98论文数:708被引数:4.5万
B
Britta Weigelt
H 指数:97论文数:1,083被引数:3.5万
J
Jorge S. Reis‐Filho
H 指数:153论文数:1,521被引数:9.5万
H
Holly E. Barker
H 指数:21论文数:173被引数:5,589
S
Syed Haider
H 指数:52论文数:432被引数:1.4万
F
Frances Daley
H 指数:33论文数:145被引数:4,587
A
Anne Vincent‐Salomon
H 指数:110论文数:1,076被引数:6.5万