Darren L. Riley - Publications, H-index & Citations

Darren L. Riley

university of pretoria

16H指数

52论文数

931被引数

收录论文 22

发表时间

Integrated computational and automated flow synthesis platform for the rapid discovery of N-benzylpiperidine acetylcholinesterase inhibitors 集成计算与自动化流合成平台，用于快速发现N-苄基哌啶乙酰胆碱酯酶抑制剂

European Journal of Medicinal Chemistry

IF5.9

2026-08-28

OAAI

A. Michelle Reinhardt; Anjo Theron; Asongwe Lionel Ateh Tantoh; Frederick P. Malan; Jenny-Lee Panayides; Darren L. Riley

A high surface area silica-supported aldehyde as a flow-compatible amine scavenger 高比表面积硅胶负载的醛作为流动相兼容的胺捕集剂

RSC Advances

IF4.6

2026-06-08

PREAI

Reinhardt, A. Michelle; Panayides, Jenny-Lee; Riley, Darren L.

Advances in solid handling for continuous flow synthesis of specialty chemicals and pharmaceuticals 固体处理在专用化学品和制药连续流合成方面的进展

Communications Chemistry

IF6.2

2026-02-23

OAAI

Zen Johnston; Thabo Peme; Tommy Mabasa; Christophe Len; Darren Riley; Jenny-Lee Panayides; Cloudius Ray Sagandira

Revitalised Hofmann carbylamine synthesis made possible with flow chemistry

REACTION CHEMISTRY & ENGINEERING

IF3.1

2025-11-01

OAAI

Johnston, Zen; Jugmohan, Jaimee; Panayides, Jenny-Lee; Riley, Darren Lyall

Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki-Miyaura coupling reactions under flow conditions

REACTION CHEMISTRY & ENGINEERING

IF3.1

2025-04-01

OAAI

Ramaotsoa, G. Valerie; Strydom, Ian; Panayides, Jenny-Lee; Riley, Darren

The synthesis of bupropion hydrochloride under greener and safer conditions utilizing flow technologies

REACTION CHEMISTRY & ENGINEERING

IF3.1

2024-01-01

OAAI

van Wyk, Lorinda T.; Neyt, Nicole C.; Jugmohan, Jaimee; Panayides, Jenny-Lee; Riley, Darren L.

The role of silicon in drug discovery: a review

RSC MEDICINAL CHEMISTRY

IF3.6

2024-01-01

OAAI

Panayides, Jenny-Lee; Riley, Darren Lyall; Hasenmaile, Felix; van Otterlo, Willem A. L.

Discovery of Novel Acetylcholinesterase Inhibitors by Virtual Screening, In Vitro Screening, and Molecular Dynamics Simulations

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2022-02-10

PREAI

van der Westhuizen, C. Johan; Stander, Andre; Riley, Darren L.; Panayides, Jenny-Lee

A Molecular-Wide and Electron Density-Based Approach in Exploring Chemical Reactivity and Explicit Dimethyl Sulfoxide (DMSO) Solvent Molecule Effects in the Proline Catalyzed Aldol Reaction

MOLECULES

IF4.6

2022-01-31

OAAI

Cukrowski, Ignacy; Dhimba, George; Riley, Darren L.

Design and testing of an ozonolysis reactor module with on-the-fly ozone degassing under flow conditions

REACTION CHEMISTRY & ENGINEERING

IF3.1

2022-01-01

OAAI

Neyt, Nicole C.; van der Westhuizen, C. Johan; Panayides, Jenny-Lee; Riley, Darren L.

Assessing a sustainable manufacturing route to lapatinib

REACTION CHEMISTRY & ENGINEERING

IF3.1

2022-01-01

OAAI

Stark, Roderick T.; Pye, Dominic R.; Chen, Wenyi; Newton, Oliver J.; Deadman, Benjamin J.; Miller, Philip W.; Panayides, Jenny-Lee; Riley, Darren L.; Hellgardt, Klaus; Hii, King Kuok (Mimi)

Use of open-source software platform to develop dashboards for control and automation of flow chemistry equipment

DIGITAL DISCOVERY

IF5.6

2022-01-01

OAAI

van der Westhuizen, C. Johan; du Toit, Jurie; Neyt, Nicole; Riley, Darren; Panayides, Jenny-Lee

Rapid formation of 2-lithio-1-(triphenylmethyl)imidazole and substitution reactions in flow

REACTION CHEMISTRY & ENGINEERING

IF3.1

2021-01-01

OAAI

Wang, Simeng; Panayides, Jenny-Lee; Riley, Darren; Tighe, Christopher J.; Hellgardt, Klaus; Hii, King Kuok (Mimi); Miller, Philip W.

Application of reactor engineering concepts in continuous flow chemistry: a review

REACTION CHEMISTRY & ENGINEERING

IF3.1

2021-01-01

OAAI

Neyt, Nicole C.; Riley, Darren L.

Improved batch and flow syntheses of the nonsteroidal anti-inflammatory COX-2 inhibitor celecoxib

REACTION CHEMISTRY & ENGINEERING

IF3.1

2021-01-01

OAAI

Scholtz, Chantal; Riley, Darren L.

Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease 新型N-苄基哌啶甲酰胺衍生物作为潜在的胆碱酯酶抑制剂，用于治疗阿尔茨海默氏病

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-10-01

PREAI

van Greunen, Divan G.; van der Westhuizen, C. Johan; Cordier, Werner; Nell, Margo; Stander, Andre; Steenkamp, Vanessa; Panayides, Jenny-Lee; Riley, Darren L.

Landscape and opportunities for active pharmaceutical ingredient manufacturing in developing African economies 发展中非洲经济体中活性药物成分制造的前景和机遇

REACTION CHEMISTRY & ENGINEERING

IF3.1

2019-01-01

PREAI

Riley, Darren L.; Strydom, Ian; Chikwamba, Rachel; Panayides, Jenny-Lee

Immobilized tetrakis(triphenylphosphine)palladium(0) for Suzuki-Miyaura coupling reactions under flow conditions (Publication with Expression of Concern. See APR, 2025)

REACTION CHEMISTRY & ENGINEERING

IF3.1

2019-01-01

PREAI

Ramaotsoa, G. Valerie; Strydom, Ian; Panayides, Jenny-Lee; Riley, Darren