宋

宋肖玲 (Xiaoling Song)

Yale University

H指数:37

被引数:6,218

个人简介

任职于上海科技大学免疫化学研究所，任研究助理教授。2011年4月至2015年2月在美国耶鲁大学医学院耶鲁综合癌症中心从事博士后研究。2004年至2010年在美国爱荷华州立大学分子生物化学、生物物理与分子生物学系遗传学专业攻读博士学位。

教育背景

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工作经历

暂无内容

荣誉奖项

暂无内容

Amiloride synergizes with EGFR PROTACs and inhibitors to overcome therapeutic resistance in NSCLC

Amiloride与EGFR PROTACs和抑制剂协同作用，以克服NSCLC中的治疗耐药性。

Bioorganic Chemistry

IF4.7

2025-06-040

PRE

The 2023 National Proficiency Test for molecular detection of shrimp infectious myonecrosis virus (IMNV) in China

AQUACULTURE

IF3.9

2025-02-010

PRE

Association between sleep regularity and arterial stiffness among middle-age adults in Southwestern China

中国西南地区中年人睡眠规律与动脉僵硬度的关系

BMC PUBLIC HEALTH

IF3.6

2024-09-170

OAAI

TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer

CANCER LETTERS

IF10.1

2024-06-013

PRE

National proficiency test for molecular detection of white spot syndrome virus in China, 2021

AQUACULTURE

IF3.9

2023-08-010

PRE

Utilization of macrocyclic peptides to target protein-protein interactions in cancer

FRONTIERS IN ONCOLOGY

IF3.3

2022-11-178

OAAI

rhG-CSF is associated with an increased risk of metastasis in NSCLC patients following postoperative chemotherapy

BMC CANCER

IF3.4

2022-07-076

OAAI

Modified FOLFIRINOX for unresectable locally advanced or metastatic gallbladder cancer, a comparison with GEMOX regimen

HEPATOBILIARY SURGERY AND NUTRITION

IF7.8

2021-08-0120

Discovery of a Brigatinib Degrader SIAIS164018 with Destroying Metastasis-Related Oncoproteins and a Reshuffling Kinome Profile

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-06-1726

PREAI

Two novel strategies to overcome the resistance to ALK tyrosine kinase inhibitor drugs: Macrocyclic inhibitors and proteolysis-targeting chimeras

MEDCOMM

IF10.7

2021-06-1738

OAAI

Effective degradation of EGFRL858R+T790M mutant proteins by CRBN-based PROTACs through both proteosome and autophagy/lysosome degradation systems

基于CRBN的protac通过蛋白体和自噬/溶酶体降解系统有效降解EGFRL858R T790M突变蛋白

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-06-0174

PREAI

Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

基于结构的发现SIAIS001作为由阿来替尼构建的口服生物利用度ALK降解剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-05-0133

PREAI

Combretastatin A4-derived payloads for antibody-drug conjugates

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-04-0112

PREAI

Spotlight on a novel bactericidal mechanism and a novel SXT/R391-like integrative and conjugative element, carrying multiple antibiotic resistance genes, in Pseudoalteromonas flavipulchra strain CDM8

MICROBIOLOGICAL RESEARCH

IF6.9

2021-01-0112

OAAI

Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance

开发布格替尼降解剂 (SIAIS117) 作为ALK阳性癌症耐药性的潜在治疗方法

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-05-0167

PREAI

Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis (vol 117, pg 7851, 2020)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-04-200

OAAI

Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-2031

OAAI

The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma

CLINICAL CANCER RESEARCH

IF10.2

2019-11-0143

OAAI

Liensinine induces gallbladder cancer apoptosis and G2/M arrest by inhibiting ZFX-induced PI3K/AKT pathway

莲心碱通过抑制ZFX诱导的PI3K/AKT通路诱导胆囊癌细胞凋亡和G2/M期阻滞

ACTA BIOCHIMICA ET BIOPHYSICA SINICA

IF3.4

2019-05-1034

PREAI

Pseudoalteromonas probiotics as potential biocontrol agents improve the survival of Penaeus vannamei challenged with acute hepatopancreatic necrosis disease (AHPND)-causing Vibrio parahaemolyticus

假交替单胞菌益生菌作为潜在的生物防治剂，可改善因引起副溶血性弧菌的急性肝胰腺坏死病 (AHPND) 引起的南美白对虾的存活率

AQUACULTURE

IF3.9

2018-09-0189

PREAI

宋肖玲 (Xiaoling Song)

个人简介

教育背景

工作经历

荣誉奖项

研究方向