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C

Carine Giovannangeli

inserm unité mixte de recherche 1154
H指数:39
被引数:4,973

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A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease

一种用于重写γ-球蛋白启动子并重新激活胎儿血红蛋白以治疗镰状细胞病的碱基编辑策略

Blood
IF23.1
2025-08-280
OAAI
Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression

Γ-珠蛋白顺式调节元件的碱基编辑介导的解剖,用于胎儿血红蛋白表达的治疗性再激活

2022-11-0434
OAAI
De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK plus ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells
2022-03-044
OAAI
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype
2020-02-14108
OAAI
Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models
2018-08-0123
PREAI
Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases
2016-03-01264
OAAI