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A
Anup Ramachandran
University of Kansas Medical Center
57
H指数
202
论文数
1.3W
被引数
0
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96
发表时间
发表时间
IF
被引数
Differentiating hepatic and renal toxicity reveals CYP-independent mechanisms of acetaminophen-induced acute kidney injury
区分肝脏和肾脏毒性揭示了对乙酰氨基酚诱导急性肾损伤的CYP非依赖性机制
Toxicology
IF
4.6
2026-08-22
0
OA
AI
Yasaman Etemadi; Timothy A. Fields; Anup Ramachandran; Hartmut Jaeschke
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Imaging Bioactive Lipid Isomers in Acetaminophen-Induced Liver Injury using Nano-DESI Tandem Mass Spectrometry
利用纳米DESI串联质谱技术成像对乙酰氨基酚诱导的肝损伤中的生物活性脂质异构体
Journal of Lipid Research
IF
4.1
2026-02-10
0
OA
AI
Miranda R. Weigand; Jepthe Yao Akakpo; Emerson Hernly; Syeda Nazifa Wali; Aiming Zheng; Anup Ramachandran; Hartmut Jaeschke; Julia Laskin
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Differential Effects on Acetaminophen-induced Nephrotoxicity and Liver Injury Following Modulation of Glutathione Resynthesis
谷胱甘肽再合成调控对对乙酰氨基酚诱导的肾毒性和肝损伤的差异性影响
Food and Chemical Toxicology
IF
3.5
2025-12-09
0
OA
AI
Yasaman Etemadi; Jephte Y. Akakpo; Timothy A. Fields; Anup Ramachandran; Hartmut Jaeschke
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Comments on: “Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury”
评论:“Formoterol,一种临床批准的药物,通过抑制脂质过氧化来抑制 ferroptosis,并减轻 APAP 诱导的急性肝损伤”
Chemico-Biological Interactions
IF
5.4
2025-11-04
0
PRE
AI
Hartmut Jaeschke; Anup Ramachandran
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The endothelial growth factor angiopoietin-2 is an accurate prognostic biomarker in patients with acetaminophen-induced acute liver failure
内皮生长因子血管生成素-2是乙酰氨基酚诱导的急性肝衰竭患者中一个准确的预后生物标志物。
TOXICOLOGICAL SCIENCES
IF
4.1
2025-10-01
1
PRE
AI
Umbaugh, David S.; Nguyen, Nga T.; Curry, Steven C.; Rule, Jody A.; Lee, William M.; Ramachandran, Anup; Jaeschke, Hartmut
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Can Acetaminophen be Used as a Chemotherapeutic Agent in the Kidney?
阿司匹林能否作为肾部的化疗药物使用?
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
IF
2.8
2025-10-01
0
PRE
AI
Jaeschke, Hartmut; Akakpo, Jephte Y.; Ramachandran, Anup
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Influence of C57BL/6 Sub-Strain on the Innate Immune Response and Liver Recovery Following Acetaminophen-Induced Liver Injury
C57BL/6亚系对乙酰氨基酚诱导的肝损伤后固有免疫反应和肝脏恢复的影响
Journal of Biochemical and Molecular Toxicology
IF
2.8
2025-08-18
0
PRE
AI
Giselle Sanchez-Guerrero; Diego K. Chavez; Hartmut Jaeschke; Anup Ramachandran
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Platelets mediate neutrophil infiltration and exacerbate liver injury and sinusoidal endothelial cell damage after a severe acetaminophen overdose in mice
血小板介导中性粒细胞浸润,并加剧小鼠严重对乙酰氨基酚过量后的肝损伤和窦状内皮细胞损伤。
Archives of Toxicology
IF
6.9
2025-08-16
0
PRE
AI
Olamide B. Adelusi; Caitlin Schneider; Caylie McKimens; James P. Luyendyk; Anup Ramachandran; Hartmut Jaeschke
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Iron supplementation switches mode of cell death to ferroptosis during acetaminophen-induced liver injury in mice rendering it resistant to N-acetylcysteine
铁补充剂在乙酰氨基酚诱导的小鼠肝损伤过程中,将细胞死亡模式转变为铁死亡,使其对N-乙酰半胱氨酸产生抵抗。
Toxicology
IF
4.6
2025-06-18
0
OA
AI
Olamide B. Adelusi; Aparna Venkatraman; Jephte Y. Akakpo; Anup Ramachandran; Hartmut Jaeschke
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4-Methylpyrazole-mediated inhibition of cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity
4-甲基吡唑介导的细胞色素P450 2E1抑制保护肾上皮细胞,但不保护膀胱癌细胞,免受顺铂毒性影响。
TOXICOLOGICAL SCIENCES
IF
4.1
2025-05-05
0
PRE
AI
Akakpo, Jephte Y.; Abbott, Erika; Woolbright, Benjamin L.; Ramachandran, Anup; Schnellmann, Rick G.; Wallace, Darren P.; Taylor, John A.
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The Endothelial Growth Factor Angiopoeitin-2 is a Prognostic Biomarker in Patients with Acetaminophen-Induced Acute Liver Failure
内皮生长因子血管生成素-2是乙酰氨基酚诱导的急性肝衰竭患者的预后生物标志物
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF
3.8
2025-03-01
0
PRE
AI
Umbaugh, David; Nguyen, Nga; Curry, Steven; Rule, Jody; Lee, William; Ramachandran, Anup; Jaeschke, Hartmut
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Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity
TOXICOLOGICAL SCIENCES
IF
4.1
2025-02-22
0
PRE
AI
Sanchez-Guerrero, Giselle; Umbaugh, David S.; Smith, Sawyer H.; Akakpo, Jephte Y.; Jaeschke, Hartmut; Ramachandran, Anup
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Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models
TOXICOLOGICAL SCIENCES
IF
4.1
2024-12-27
1
PRE
AI
Jaeschke, Hartmut; Ramachandran, Anup
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Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure
BIOCHEMICAL PHARMACOLOGY
IF
5.6
2024-10-01
7
OA
AI
Ramachandran, Anup; Akakpo, Jephte Y.; Curry, Steven C.; Rumack, Barry H.; Jaeschke, Hartmut
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Effect of ferroptosis inhibitors in a murine model of acetaminophen-induced liver injury
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
IF
2.8
2024-07-31
3
PRE
AI
Adelusi, Olamide B.; Etemadi, Yasaman; Akakpo, Jephte Y.; Ramachandran, Anup; Jaeschke, Hartmut
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The p21+ perinecrotic hepatocytes produce the chemokine CXCL14 after a severe acetaminophen overdose promoting hepatocyte injury and delaying regeneration
TOXICOLOGY
IF
4.6
2024-05-01
1
OA
AI
Umbaugh, David S.; Nguyen, Nga T.; Smith, Sawyer H.; Ramachandran, Anup; Jaeschke, Hartmut
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The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice
血小板生成素模拟JNJ-26366821减轻对乙酰氨基酚诱导的小鼠肝损伤后的晚期损伤并加速肝脏恢复的开始
ARCHIVES OF TOXICOLOGY
IF
6.9
2024-03-29
0
PRE
AI
Adelusi, Olamide B.; Akakpo, Jephte Y.; Eichenbaum, Gary; Sadaff, Ejaz; Ramachandran, Anup; Jaeschke, Hartmut
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Comments on: Unveiling the therapeutic promise of natural products in alleviating drug-induced liver injury: Present advancements and future prospects
PHYTOTHERAPY RESEARCH
IF
6.3
2024-02-05
0
PRE
AI
Jaeschke, Hartmut; Ramachandran, Anup
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Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging
TOXICOLOGICAL SCIENCES
IF
4.1
2024-01-30
1
PRE
AI
Akakpo, Jephte Yao; Olivos, Hernando; Shrestha, Bindesh; Midey, Anthony; Jaeschke, Hartmut; Ramachandran, Anup
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Acetaminophen Hepatotoxicity: Paradigm for Understanding Mechanisms of Drug-Induced Liver Injury
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE
IF
34.5
2024-01-24
29
OA
AI
Jaeschke, Hartmut; Ramachandran, Anup
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研究方向
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合作学者
合作期刊
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