Edward P. Browne - Publications, H-index & Citations

Edward P. Browne

University of North Carolina at Chapel Hill

25H指数

131论文数

4.3K被引数

收录论文 38

发表时间

Empirical PK/PD Model for Differentiating Intrinsic Dosing Rules by Therapeutic Indication With Relevance for HIV-1 Latency Reversal 基于治疗适应症的内在给药规则区分的经验性药代动力学/药效学模型，与HIV-1潜伏期逆转的相关性

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2026-09-30

OAAI

Lauren A. R. Tompkins; Amanda Poliseno; Airlie Ward; Edward P. Browne; Cassandra Gilbert; Craig Sykes; Angela D. M. Kashuba; Mackenzie L. Cottrell

Single-cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes 单细胞表征揭示胃肠道HIV储库的异质性细胞表型

Journal of Clinical Investigation

IF13.6

2026-02-16

PREAI

Peterson, Jackson J.; Chandel, Shipra; James, Katherine; Bennett, Elizabeth S.; Wu, Vincent; White, Cory H.; Allard, Brigitte; Clohosey, Matthew; Whitaker, Taylor; Baker, Caroline; Pedersen, Susan; Peery, Anne F.; Gay, Cynthia L.; Betts, Michael R.; Margolis, David M.; Archin, Nancie M.; Browne, Edward P.

Customizable mRNA Lipid Nanoparticles for Transfection of Primary Human T Cells 可定制的mRNA脂质纳米颗粒用于原代人T细胞的转染

ACS NANO

IF16

2025-11-01

PREAI

Vankeulen-Miller, Rachel; Huff, Julia; Narasipura, Eshan A.; Browne, Edward P.; Fenton, Owen S.

The role of Vpr in a primary CD4+T-cell model of HIV-1 latency 3672

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Lewis, Catherine; Margolis, David; Patrick Browne, Edward

SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation SARS-CoV-2感染诱导促纤维化和促血栓性泡沫细胞形成

Nature Microbiology

IF19.4

2025-08-22

PREAI

Diana M. Battaglia; Claire E. Post; Wenbo Yao; Angela Wahl; Lisa E. Gralinski; Hongwei Liu; Hong Dang; Victoria J. Madden; Kristen K. White; Sarah R. Leist; Kenneth H. Dinnion; Gabriela De la Cruz; Bentley R. Midkiff; Heather M. Froggatt; Kendra Gully; Mark Zweigart; J. Rachel Reader; Katherine J. Olstad; Jeffrey I. Everitt; Koen K. A. Van Rompay; Kristina De Paris; Eniko Sajti; Raymond J. Pickles; Edward P. Browne; Corbin D. Jones; Richard C. Boucher; Ralph S. Baric; J. Victor Garcia

A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency

PLOS PATHOGENS

IF4.9

2025-04-01

OAAI

Ashokkumar, Manickam; Hafer, Terry L.; Felton, Abby; Archin, Nancie M.; Margolis, David M.; Emerman, Michael; Browne, Edward P.

Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir

MBIO

IF4.7

2024-09-11

OAAI

Ling, Lijun; Kim, Manse; Soper, Andrew; Kovarova, Martina; Spagnuolo, Rae Ann; Begum, Nurjahan; Kirchherr, Jennifer; Archin, Nancie; Battaglia, Diana; Cleveland, Dave; Wahl, Angela; Margolis, David M.; Browne, Edward P.; Garcia, J. Victor

The histone methyltransferase SETD2 regulates HIV expression and latency

PLOS PATHOGENS

IF4.9

2024-06-07

OAAI

Bussey-Sutton, Cameron R.; Ward, Airlie; Fox, Joshua A.; Turner, Anne-Marie W.; Peterson, Jackson J.; Emery, Ann; Longoria, Arturo R.; Gomez-Martinez, Ismael; Jones, Corbin; Hepperla, Austin; Margolis, David M.; Strahl, Brian D.; Browne, Edward P.

THE ROLE OF THE VIRAL PROTEIN VPR IN THE EPIGENETIC REGULATION OF HIV-1 LATENCY

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

PREAI

Lewis, Catherine; Browne, Edward

A novel high-throughput microwell outgrowth assay for HIV-infected cells

JOURNAL OF VIROLOGY

IF3.8

2024-03-19

OAAI

Fenton, Anthony D.; Archin, Nancie; Turner, Anne-Marie; Joseph, Sarah; Moeser, Matthew; Margolis, David M.; Browne, Edward P.

Azetidines Kill Multidrug-Resistant Mycobacterium tuberculosis without Detectable Resistance by Blocking Mycolate Assembly Azetidines通过阻断Mycolate组装杀死多药耐药结核分枝杆菌而没有可检测的耐药性

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-02-08

OAAI

Cui, Yixin; Lanne, Alice; Peng, Xudan; Browne, Edward; Bhatt, Apoorva; Coltman, Nicholas J.; Craven, Philip; Cox, Liam R.; Cundy, Nicholas J.; Dale, Katie; Feula, Antonio; Frampton, Jon; Fung, Martin; Morton, Michael; Goff, Aaron; Salih, Mariwan; Lang, Xingfen; Li, Xingjian; Moon, Chris; Pascoe, Jordan; Portman, Vanessa; Press, Cara; Schulz-Utermoehl, Timothy; Lee, Suki; Tortorella, Micky D.; Tu, Zhengchao; Underwood, Zoe E.; Wang, Changwei; Yoshizawa, Akina; Zhang, Tianyu; Waddell, Simon J.; Bacon, Joanna; Alderwick, Luke; Fossey, John S.; Neagoie, Cleopatra

A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells 组蛋白去乙酰化酶网络调节HIV感染细胞中的表观遗传重编程和病毒沉默

CELL CHEMICAL BIOLOGY

IF7.2

2023-12-01

OAAI

Peterson, Jackson J.; Lewis, Catherine A.; Burgos, Samuel D.; Manickam, Ashokkumar; Xu, Yinyan; Rowley, Allison A.; Clutton, Genevieve; Richardson, Brian; Zou, Fei; Simon, Jeremy M.; Margolis, David M.; Goonetilleke, Nilu; Browne, Edward P.

Impact of Cannabis Use on Immune Cell Populations and the Viral Reservoir in People With HIV on Suppressive Antiretroviral Therapy

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2023-08-22

OAAI

Falcinelli, Shane D.; Cooper-Volkheimer, Alicia D.; Semenova, Lesia; Wu, Ethan; Richardson, Alexander; Ashokkumar, Manickam; Margolis, David M.; Archin, Nancie M.; Rudin, Cynthia D.; Murdoch, David; Browne, Edward P.

New Concepts in Therapeutic Manipulation of HIV-1 Transcription and Latency: Latency Reversal versus Latency Prevention

VIRUSES-BASEL

IF3.5

2023-07-31

OAAI

Lewis, Catherine A.; Margolis, David M.; Browne, Edward P.

Automated microarray platform for single-cell sorting and collection of lymphocytes following HIV reactivation

BIOENGINEERING & TRANSLATIONAL MEDICINE

IF5.7

2023-06-21

OAAI

Cortes-Llanos, Belen; Jain, Vaibhav; Cooper-Volkheimer, Alicia; Browne, Edward P. P.; Murdoch, David M. M.; Allbritton, Nancy L. L.

A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency

PLOS PATHOGENS

IF4.9

2023-01-27

OAAI

Hsieh, Emily; Janssens, Derek H. A.; Paddison, Patrick J. E.; Browne, Edward P. A.; Henikoff, Steve E.; OhAinle, Molly A.; Emerman, Michael E.

Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization

COMMUNICATIONS BIOLOGY

IF5.1

2022-07-19

OAAI

Huang, Haiyang; Wang, Yingfan; Rudin, Cynthia; Browne, Edward P.

Crotonate sensitizes IAPi in the disruption of latent HIV by modulating the ncNF-κB signaling pathway at the step of p100 cleavage into p52 巴豆酸盐通过在p100裂解为p52的步骤中调节ncnf-κb信号通路，使IAPi在潜伏HIV的破坏中敏感。

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Jiang, Guochun; Li, Dajiang; Falcinelli, Shane D.; Wong, Lilly M.; Tang, Yuyang; Browne, Edward P.; Archin, Nancie M.; Margolis, David M.

Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo 联合非规范nf-κb激动和靶向BET溴结构域抑制逆转HIV体外潜伏期

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-04-15

OAAI

Falcinelli, Shane D.; Peterson, Jackson J.; Turner, Anne-Marie W.; Irlbeck, David; Read, Jenna; Raines, Samuel L. M.; James, Katherine S.; Sutton, Cameron; Sanchez, Anthony; Emery, Ann; Sampey, Gavin; Ferris, Robert; Allard, Brigitte; Ghofrani, Simon; Kirchherr, Jennifer L.; Baker, Caroline; Kuruc, JoAnn D.; Gay, Cynthia L.; James, Lindsey I.; Wu, Guoxin; Zuck, Paul; Rioja, Inmaculada; Furze, Rebecca C.; Prinjha, Rab K.; Howell, Bonnie J.; Swanstrom, Ronald; Browne, Edward P.; Strahl, Brian D.; Dunham, Richard M.; Archin, Nancie M.; Margolis, David M.

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

PLOS PATHOGENS

IF4.9

2021-02-26

OAAI

Jefferys, Stuart R.; Burgos, Samuel D.; Peterson, Jackson J.; Selitsky, Sara R.; Turner, Anne-Marie; James, Lindsey I.; Tsai, Yi-Hsuan; Coffey, Alisha R.; Margolis, David M.; Parker, Joel; Browne, Edward P.

研究方向