Alejandro Reyes - Publications, H-index & Citations

Alejandro Reyes

novartis biomedical research

29H指数

115论文数

9.8K被引数

收录论文 24

发表时间

Specificity and exon target space of splicing modifying compounds 剪接修饰化合物的特异性及其外显子靶标空间

Nature Communications

IF15.7

2026-07-04

OAAI

Felina Lenkeit; Judith Knehr; Marc Altorfer; Andrea Byrnes; Wenjing Li; Jack Hsiao; Connie Wu; Priti Gaitonde; Philip R. Skaanderup; Steve Mullin; Elizaveta Solovyeva; Michal Pikusa; Andrew T. Krueger; Johannes Ottl; Caroline Gubser Keller; Christian Kolter; Ulrike Naumann; Philipp Ottis; Alejandro Reyes

The transcription factor ZNF469 regulates collagen production in liver fibrosis 转录因子ZNF469调控肝纤维化中的胶原蛋白产生

JCI INSIGHT

IF6.1

2025-02-25

OAAI

Steinhauser, Sebastian; Estoppey, David; Buehler, Dennis P.; Xiong, Yanhua; Pizzato, Nicolas; Rietsch, Amandine; Wu, Fabian; Leroy, Nelly; Wunderlin, Tiffany; Claerr, Isabelle; Tropberger, Philipp; Muller, Miriam; Vissieres, Alexandra; Davison, Lindsay M.; Farber-Eger, Eric; Wells, Quinn S.; Sheng, Quanhu; Bergling, Sebastian; Wild, Sophia; Moulin, Pierre; Liang, Jiancong; English, Wayne J.; Williams, Brandon; Knehr, Judith; Altorfer, Marc; Reyes, Alejandro; Voshol, Johannes; Mickanin, Craig; Hoepfner, Dominic; Nigsch, Florian; Frederiksen, Mathias; Flynn, Charles R.; Fodor, Barna D.; Brown, Jonathan D.; Kolter, Christian

An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion

NATURE COMMUNICATIONS

IF15.7

2022-03-03

OAAI

Keller, Caroline Gubser; Shin, Youngah; Monteys, Alex Mas; Renaud, Nicole; Beibel, Martin; Teider, Natalia; Peters, Thomas; Faller, Thomas; St-Cyr, Sophie; Knehr, Judith; Roma, Guglielmo; Reyes, Alejandro; Hild, Marc; Lukashev, Dmitriy; Theil, Diethilde; Dales, Natalie; Cha, Jang-Ho; Borowsky, Beth; Dolmetsch, Ricardo; Davidson, Beverly L.; Sivasankaran, Rajeev

Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization

BIOPHYSICAL JOURNAL

IF3.1

2020-11-01

OAAI

Qi, Yifeng; Reyes, Alejandro; Johnstone, Sarah E.; Aryee, Martin J.; Bernstein, Bradley E.; Zhang, Bin

A practical guide to methods controlling false discoveries in computational biology 控制计算生物学中错误发现的方法的实用指南

GENOME BIOLOGY

IF9.4

2019-06-04

251

OAAI

Korthauer, Keegan; Kimes, Patrick K.; Duvallet, Claire; Reyes, Alejandro; Subramanian, Ayshwarya; Teng, Mingxiang; Shukla, Chinmay; Alm, Eric J.; Hicks, Stephanie C.

Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2019-05-01

PREAI

Pena, Eduardo; Roa, Francisco J.; Inostroza, Eveling; Sotomayor, Kirsty; Gonzalez, Mauricio; Gutierrez-Castro, Francisco A.; Maurin, Michelle; Sweet, Karen; Labrousse, Claire; Gatica, Marcell; Aylwin, Carlos F.; Mendoza, Pamela; Maldonado, Mafalda; Delgado, Carolina; Madariaga, Jaime; Panes, Jessica; Silva-Grecchi, Tiare; Concha, Ilona I.; Moraga-Cid, Gustavo; Reyes, Alejandro M.; Munoz-Montesino, Carola; Carlos Vera, Juan; Rivas, Coralia, I

CTCF-Mediated Chromatin Loops between Promoter and Gene Body Regulate Alternative Splicing across Individuals

CELL SYSTEMS

IF7.7

2017-12-01

OAAI

Ruiz-Velasco, Mariana; Kumar, Manjeet; Lai, Mang Ching; Bhat, Pooja; Solis-Pinson, Ana Belen; Reyes, Alejandro; Kleinsorg, Stefan; Noh, Kyung-Min; Gibson, Toby J.; Zaugg, Judith B.

Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues

NUCLEIC ACIDS RESEARCH

IF13.1

2017-11-30

180

OAAI

Reyes, Alejandro; Huber, Wolfgang

Supervised Event Coding From Text Written in Spanish: Introducing Eventus ID

computer science review

IF2.7

2016-01-08

PREAI

Osorio, Javier; Reyes, Alejandro

E2f3 in tumor macrophages promotes lung metastasis

ONCOGENE

IF7.3

2015-11-09

OAAI

Trikha, P.; Sharma, N.; Pena, C.; Reyes, A.; Pecot, T.; Khurshid, S.; Rawahneh, M.; Moffitt, J.; Stephens, J. A.; Fernandez, S. A.; Ostrowski, M. C.; Leone, G.

Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells

NATURE IMMUNOLOGY

IF27.6

2015-08-03

132

OAAI

Brennecke, Philip; Reyes, Alejandro; Pinto, Sheena; Rattay, Kristin; Nguyen, Michelle; Kuechlert, Rita; Huber, Wolfgang; Kyewski, Bruno; Steinmetz, Lars M.

Cis-regulatory elements involved in species-specific transcriptional regulation of the SVCT1 gene in rat and human hepatoma cells

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2015-08-01

PREAI

Munoz, Alejandra; Villagran, Marcelo; Guzman, Paula; Soliz, Carlos; Gatica, Marcell; Aylwin, Carlos; Sweet, Karen; Maldonado, Mafalda; Escobar, Elizabeth; Reyes, Alejandro M.; Toledo, Jorge R.; Sanchez, Oliberto; Onate, Sergio A.; Carlos Vera, Juan; Rivas, Coralia I.

Orchestrating high-throughput genomic analysis with Bioconductor 使用Bioconductor协调高通量基因组分析

NATURE METHODS

IF32.1

2015-01-29

2.5K

OAAI

Huber, Wolfgang; Carey, Vincent J.; Gentleman, Robert; Anders, Simon; Carlson, Marc; Carvalho, Benilton S.; Bravo, Hector Corrada; Davis, Sean; Gatto, Laurent; Girke, Thomas; Gottardo, Raphael; Hahne, Florian; Hansen, Kasper D.; Irizarry, Rafael A.; Lawrence, Michael; Love, Michael I.; MacDonald, James; Obenchain, Valerie; Oles, Andrzej K.; Pages, Herve; Reyes, Alejandro; Shannon, Paul; Smyth, Gordon K.; Tenenbaum, Dan; Waldron, Levi; Morgan, Martin

Transcriptome-wide Profiling and Posttranscriptional Analysis of Hematopoietic Stem/Progenitor Cell Differentiation toward Myeloid Commitment

STEM CELL REPORTS

IF5.1

2014-11-01

OAAI

Klimmeck, Daniel; Cabezas-Wallscheid, Nina; Reyes, Alejandro; von Paleske, Lisa; Renders, Simon; Hansson, Jenny; Krijgsveld, Jeroen; Huber, Wolfgang; Trumpp, Andreas

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

CELL STEM CELL

IF20.4

2014-10-01

437

OAAI

Cabezas-Wallscheid, Nina; Klimmeck, Daniel; Hansson, Jenny; Lipka, Daniel B.; Reyes, Alejandro; Wang, Qi; Weichenhan, Dieter; Lier, Amelie; von Paleske, Lisa; Renders, Simon; Wuensche, Peer; Zeisberger, Petra; Brocks, David; Gu, Lei; Herrmann, Carl; Haas, Simon; Essers, Marieke A. G.; Brors, Benedikt; Eils, Roland; Huber, Wolfgang; Milsom, Michael D.; Plass, Christoph; Krijgsveld, Jeroen; Trumpp, Andreas

Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2014-05-01

PREAI

Munoz-Montesino, Carola; Roa, Francisco J.; Pena, Eduardo; Gonzalez, Mauricio; Sotomayor, Kirsty; Inostroza, Eveling; Munoz, Carolina A.; Gonzalez, Ivan; Maldonado, Mafalda; Soliz, Carlos; Reyes, Alejandro M.; Vera, Juan Carlos; Rivas, Coralia I.

Drift and conservation of differential exon usage across tissues in primate species

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-09-03

OAAI

Reyes, Alejandro; Anders, Simon; Weatheritt, Robert J.; Gibson, Toby J.; Steinmetz, Lars M.; Huber, Wolfgang

Treatment of symptomatic congenital cytomegalovirus infection beyond the neonatal period

JOURNAL OF CLINICAL VIROLOGY

IF3.4

2012-09-01

PREAI

del Rosal, Teresa; Baquero-Artigao, Fernando; Blazquez, Daniel; Noguera-Julian, Antoni; Moreno-Perez, David; Reyes, Alejandro; Vilas, Javier

Detecting differential usage of exons from RNA-seq data 从rna-seq数据中检测外显子的差异使用

GENOME RESEARCH

IF5.5

2012-06-21

1.3K

OAAI

Anders, Simon; Reyes, Alejandro; Huber, Wolfgang

Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2012-05-01

PREAI

Mardones, Lorena; Zuniga, Felipe A.; Villagran, Marcelo; Sotomayor, Kirsty; Mendoza, Pamela; Escobar, David; Gonzalez, Mauricio; Ormazabal, Valeska; Maldonado, Mafalda; Onate, Gloria; Angulo, Constanza; Concha, Ilona I.; Reyes, Alejandro M.; Carcamo, Juan G.; Barra, Valeria; Carlos Vera, Juan; Rivas, Coralia I.

研究方向