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S

Sainitin Donakonda

technical university of munich
H指数:16
被引数:1,658
浏览量:0

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Single-cell systems network and machine learning dissection of ferroptosis in recurrent glioblastoma highlights astrocytic ZFP36 as a therapeutic hub for network medicine repurposing

单细胞系统网络和机器学习方法对复发胶质母细胞瘤中铁死亡的分析，突出了星形胶质细胞中的ZFP36作为网络医学药物重定位的疗法枢纽。

European Journal of Cancer
IF7.1
2026-02-170
OAAI
Mahima Kishinani; Manoj Girish; Swati Sinha; Sainitin Donakonda
Drug repurposing identifies novel Wee1 kinase inhibitors for triple negative breast cancer therapeutics

药物重定位确定了用于三阴性乳腺癌治疗的新型Wee1激酶抑制剂

European Journal of Medicinal Chemistry
IF5.9
2025-11-060
PRE
Jisha Pillai U; Prabhjot Singh; Meenu Maan; Manju Nidagodu Jayakumar; Sainitin Donakonda; Eldhose Iype; Mainak Dutta
Two-layered immune escape in AML is overcome by Fcγ receptor activation and inhibition of PGE2 signaling in NK cells

AML中的两层免疫逃逸被NK细胞中Fcγ受体的激活和PGE2信号通路的抑制所克服。

BLOOD
IF23.1
2025-01-211
OA
Rothfuss, Charlotte; Baumann, Tobias; Donakonda, Sainitin; Brauchle, Bettina; Marcinek, Anetta; Urban, Christian; Mergner, Julia; Pedde, Anna-Marie; Hirschberger, Anna; Krupka, Christina; Neumann, Anne-Sophie; Haenel, Gerulf; Merten, Camilla; Oellinger, Rupert; Hecker, Judith S.; Bauer, Tanja; Schmid, Christian; Goetze, Katharina S.; Altomonte, Jennifer; Buecklein, Veit; Jacobs, Roland; Rad, Roland; Dawid, Corina; Simeoni, Luca; Schraven, Burkhart; Pichlmair, Andreas; Subklewe, Marion; Knolle, Percy A.; Boettcher, Jan P.; Hoechst, Bastian
Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity
CELL REPORTS
IF6.9
2024-11-010
OAAI
Pedde, Anna-Marie; Kim, Hyunu; Donakonda, Sainitin; Baumann, Tobias; Bayerl, Felix; Meiser, Philippa; Hirschberger, Anna; Klement, Christine; Grassmann, Simon; Oellinger, Rupert; Hueser, Norbert; Hartmann, Daniel; Laschinger, Melanie; Trapani, Joseph A.; Zippelius, Alfred; Bald, Tobias; Wiedemann, Gabriela M.; Rad, Roland; Sun, Joseph C.; Hoechst, Bastian; Boettcher, Jan P.
Comprehensive in-silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small molecular inhibitors for the treatment of Cholangiocarcinoma (vol 166, 107572, 2023)
COMPUTERS IN BIOLOGY AND MEDICINE
IF6.3
2024-01-010
OAAI
Jayakumar, Manju Nidagodu; Muhammad, Jibran Sualeh; Dutta, Mainak; Donakonda, Sainitin
Comprehensive In silico analysis of chaperones identifies CRYAB and P4HA2 as potential therapeutic targets and their small-molecule inhibitors for the treatment of cholangiocarcinoma
COMPUTERS IN BIOLOGY AND MEDICINE
IF6.3
2023-11-010
PRE
Jayakumar, Manju Nidagodu; Muhammad, Jibran Sualeh; Dutta, Mainak; Donakonda, Sainitin
Characterization of tumor microenvironment in glioblastoma multiforme identifies ITGB2 as a key immune and stromal related regulator in glial cell types
COMPUTERS IN BIOLOGY AND MEDICINE
IF6.3
2023-10-018
PRE
Krishna, A. V. S. Sai; Ramu, Alagammai; Hariharan, Srimathangi; Sinha, Swati; Donakonda, Sainitin
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

肿瘤来源的前列腺素E2程序cDC1功能障碍损害肿瘤内组织的抗癌T细胞反应

IMMUNITY
IF26.3
2023-06-0162
OA
Bayerl, Felix; Meiser, Philippa; Donakonda, Sainitin; Hirschberger, Anna; Lacher, Sebastian B.; Pedde, Anna-Marie; Hermann, Chris D.; Elewaut, Anais; Knolle, Moritz; Ramsauer, Lukas; Rudolph, Thomas J.; Grassmann, Simon; Oellinger, Rupert; Kirchhammer, Nicole; Trefny, Marcel; Anton, Martina; Wohlleber, Dirk; Hoechst, Bastian; Zaremba, Anne; Krueger, Achim; Rad, Roland; Obenauf, Anna C.; Schadendorf, Dirk; Zippelius, Alfred; Buchholz, Veit R.; Schraml, Barbara U.; Boettcher, Jan P.
mrhl RNA, a Long Noncoding RNA, Negatively Regulates Wnt Signaling through Its Protein Partner Ddx5/p68 in Mouse Spermatogonial Cells
MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-20119
OA
Arun, Gayatri; Akhade, Vijay Suresh; Donakonda, Sainitin; Rao, Manchanahalli R. Satyanarayana
IL-6-induced FOXO1 activity determines the dynamics of metabolism in CD8 T cells cross-primed by liver sinusoidal endothelial cells

IL-6-induced FOXO1活性决定了由肝窦内皮细胞交叉引发的CD8 T细胞的代谢动力学

CELL REPORTS
IF6.9
2022-02-0112
OA
Dudek, Michael; Lohr, Kerstin; Donakonda, Sainitin; Baumann, Tobias; Lu, Max; Hegenbarth, Silke; Duebbel, Lena; Eberhagen, Carola; Michailidou, Savvoula; Yassin, Abdallah; Prinz, Marco; Popper, Bastian; Rose-John, Stefan; Zischka, Hans; Knolle, Percy A.
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells

XIAP通过促进Paneth和树突状细胞的先天免疫反应来抑制TNF驱动的肠道炎症和生态失调

SCIENCE IMMUNOLOGY
IF16.3
2021-11-2620
OA
Wahida, Adam; Mueller, Madeleine; Hiergeist, Andreas; Popper, Bastian; Steiger, Katja; Branca, Caterina; Tschurtschenthaler, Markus; Engleitner, Thomas; Donakonda, Sainitin; De Coninck, Jordy; Oellinger, Rupert; Pfautsch, Marie K.; Mueller, Nicole; Silva, Miguel; Usluer, Sinem; Orberg, Erik Thiele; Boettcher, Jan P.; Pfarr, Nicole; Anton, Martina; Slotta-Huspenina, Julia B.; Nerlich, Andreas G.; Madl, Tobias; Basic, Marijana; Bleich, Andre; Berx, Geert; Ruland, Jurgen; Knolle, Percy A.; Rad, Roland; Adolph, Timon E.; Vandenabeele, Peter; Kanegane, Hirokazu; Gessner, Andre; Jost, Philipp J.; Yabal, Monica
Differential expression of gut miRNAs in idiopathic Parkinson's disease
PARKINSONISM & RELATED DISORDERS
IF3.4
2021-07-019
PRE
Kurz, Anna; Kumar, Rohit; Northoff, Bernd H.; Wenk, Catharina; Schirra, Joerg; Donakonda, Sainitin; Hoeglinger, Guenter U.; Schwarz, Johannes; Rozanski, Verena; Huebner, Rainer; Botzel, Kai; Holdt, Lesca Miriam; Koeglsperger, Thomas
Linear B-Cell Epitopes in Human Norovirus GII.4 Capsid Protein Elicit Blockade Antibodies
VACCINES
IF3.4
2021-01-148
OAAI
Moeini, Hassan; Afridi, Suliman Qadir; Donakonda, Sainitin; Knolle, Percy A.; Protzer, Ulrike; Hoffmann, Dieter
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes

在病毒感染的肝细胞中，TNF受体信号传导后，降低的线粒体弹性使得非典型诱导凋亡

JOURNAL OF HEPATOLOGY
IF33
2020-12-0112
PREAI
Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Klaeger, Susan; Kuester, Bernhard; Wettmarshausen, Jennifer; Mueller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hueser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Kroenke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwaelder, Mathias; Knolle, Percy A.; Wohlleber, Dirk
Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal
NATURE IMMUNOLOGY
IF27.6
2020-04-23171
PREAI
Baumann, Tobias; Dunkel, Andreas; Schmid, Christian; Schmitt, Sabine; Hiltensperger, Michael; Lohr, Kerstin; Laketa, Vibor; Donakonda, Sainitin; Ahting, Uwe; Lorenz-Depiereux, Bettina; Heil, Jan E.; Schredelseker, Johann; Simeoni, Luca; Fecher, Caroline; Koerber, Nina; Bauer, Tanja; Hueser, Norbert; Hartmann, Daniel; Laschinger, Melanie; Eyerich, Kilian; Eyerich, Stefanie; Anton, Martina; Streeter, Matthew; Wang, Tina; Schraven, Burkhart; Spiegel, David; Assaad, Farhah; Misgeld, Thomas; Zischka, Hans; Murray, Peter J.; Heine, Annkristin; Heikenwaelder, Mathias; Korn, Thomas; Dawid, Corinna; Hofmann, Thomas; Knolle, Percy A.; Hoechst, Bastian
FOXO1-activitiy controls effector function of CXCR6+CD8+T-cells and prevents liver immune pathology during viral hepatitis and non-alcoholic steatohepatitis
JOURNAL OF HEPATOLOGY
IF33
2019-04-010
PREAI
Dudek, Michael; Pfister, Dominik; Kallin, Nina; Wohlleber, Dirk; Sainitin, Donakonda; Heikenwaelder, Mathias; Knolle, Percy A.
Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-02-2075
OAAI
Matthias, Julia; Maul, Julia; Noster, Rebecca; Meinl, Hanna; Chao, Ying-Yin; Gerstenberg, Heiko; Jeschke, Florian; Gasparoni, Gilles; Welle, Anna; Walter, Joern; Nordstroem, Karl; Eberhardt, Klaus; Renisch, Dennis; Donakonda, Sainitin; Knolle, Percy; Soll, Dominik; Grabbe, Stephan; Garzorz-Stark, Natalie; Eyerich, Kilian; Biedermann, Tilo; Baumjohann, Dirk; Zielinski, Christina E.
Genome wide chromatin occupancy of mrhl RNA and its role in gene regulation in mouse spermatogonial cells
RNA BIOLOGY
IF3.4
2015-01-1328
OAAI
Akhade, Vijay Suresh; Arun, Gayatri; Donakonda, Sainitin; Rao, Manchanahalli R. Satyanarayana
Identification of Genomic Targets of Transcription Factor Aebp1 and its role in Survival of Glioma Cells
MOLECULAR CANCER RESEARCH
IF4.7
2012-08-1537
OAAI
Ladha, Jayashree; Sinha, Swati; Bhat, Vasudeva; Donakonda, Sainitin; Rao, Satyanarayana M. R.
Glioblastoma-Specific Protein Interaction Network Identifies PP1A and CSK21 as Connecting Molecules between Cell Cycle-Associated Genes
CANCER RESEARCH
IF16.6
2010-08-1422
OAAI
Ladha, Jayashree; Donakonda, Sainitin; Agrawal, Shipra; Thota, Balaram; Srividya, Mallavarapu R.; Sridevi, Sambandam; Arivazhagan, Arimappamagan; Thennarasu, Kandavel; Balasubramaniam, Anandh; Chandramouli, Bangalore A.; Hegde, Alangar Sattiyaranjandas; Kondaiah, Paturu; Somasundaram, Kumaravel; Santosh, Vani; Rao, Satyanarayana M. R.

研究方向

暂未获取到该数据
P
Percy A. Knolle
H 指数:85论文数:472被引数:2.7万
R
Roland Rad
H 指数:69论文数:428被引数:2.0万
R
Rupert Öllinger
H 指数:35论文数:184被引数:4,624
T
Tobias Baumann
H 指数:29论文数:186被引数:2,655
J
Jan P. Böttcher
H 指数:31论文数:78被引数:7,881
B
Bastian Höchst
H 指数:17论文数:41被引数:1,832
D
Daniel Hartmann
H 指数:55论文数:417被引数:1.0万
H
Hans Zischka
H 指数:51论文数:193被引数:1.0万
M
Mathias Heikenwälder
H 指数:106论文数:648被引数:4.5万
M
Martina Anton
H 指数:41论文数:120被引数:6,576