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R

Ranjitha Uppala

university of michigan system
H指数:17
被引数:1,851

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Multi-cytokine based TWAS for seven inflammatory skin disorders identify candidate causal genes in keratinocytes

基于多细胞因子法的转录组加权关联分析在七种炎症性皮肤疾病中识别角蛋白细胞中的候选因果基因

Journal of Allergy and Clinical Immunology
IF11.2
2026-05-260
OAAI
Haihan Zhang; Matthew T. Patrick; Mrinal K. Sarkar; Rachael Bogle; Qinmengge Li; Ranjitha Uppala; Bethany E. Perez White; Lynn Petukhova; Nick Dand; Philip E. Stuart; Angela M. Christiano; Michael A. Simpson; Jonathan N. Barker; Stephan Weidinger; Robert L. Modlin; Regina C. Betz; Dinesh Khanna; John Varga; J. Michelle Kahlenberg; Kevin He
Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis

整合全基因组关联研究、数量性状基因座和角质形成细胞功能实验揭示了特应性皮炎的分子机制

NATURE COMMUNICATIONS
IF15.7
2025-04-010
OA
Oliva, Meritxell; Sarkar, Mrinal K.; March, Michael E.; Saeidian, Amir Hossein; Mentch, Frank D.; Hsieh, Chen-Lin; Tang, Fanying; Uppala, Ranjitha; Patrick, Matthew T.; Li, Qinmengge; Bogle, Rachael; Kahlenberg, J. Michelle; Watson, Deborah; Glessner, Joseph T.; Youssefian, Leila; Vahidnezhad, Hassan; Tsoi, Lam C.; Gudjonsson, Johann E.; Smith, Kathleen M.; Riley-Gillis, Bridget
Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling
JCI INSIGHT
IF6.1
2024-03-123
OAAI
Jiang, Yanyun; Gruszka, Dennis; Zeng, Chang; Swindell, William R.; Gaskill, Christa; Sorensen, Christian; Brown, Whitney; Gangwar, Roopesh Singh; Tsoi, Lam C.; Webster, Joshua; Siguroardottir, Sigrun Laufey; Sarkar, Mrinal K.; Uppala, Ranjitha; Kidder, Austin; Xing, Xianying; Plazyo, Olesya; Xing, Enze; Billi, Allison C.; Maverakis, Emanual; Kahlenberg, J. Michelle; Gudjonsson, Johann E.; Ward, Nicole L.
Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes
JCI INSIGHT
IF6.1
2022-08-2216
OAAI
Merleev, Alexander A.; Le, Stephanie T.; Alexanian, Claire; Toussi, Atrin; Xie, Yixuan; Marusina, Alina, I; Watkins, Steven M.; Patel, Forum; Billi, Allison C.; Wiedemann, Julie; Izumiya, Yoshihiro; Kumar, Ashish; Uppala, Ranjitha; Kahlenberg, J. Michelle; Liu, Fu-Tong; Adamopoulos, Iannis E.; Wang, Elizabeth A.; Ma, Chelsea; Cheng, Michelle Y.; Xiong, Halani; Kirane, Amanda; Luxardi, Guillaume; Andersen, Bogi; Tsoi, Lam C.; Lebrilla, Carlito B.; Gudjonsson, Johann E.; Maverakis, Emanual
Noninvasive Tape-Stripping with High-Resolution RNA Profiling Effectively Captures a Preinflammatory State in Nonlesional Psoriatic Skin
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2022-06-0112
OAAI
Tsoi, Lam C.; Xing, Xianying; Xing, Enze; Wasikowski, Rachael; Shao, Shuai; Zeng, Chang; Plazyo, Olesya; Kirma, Joseph; Jiang, Yanyung; Billi, Allison C.; Sarkar, Mrinal K.; Turnier, Jessica L.; Uppala, Ranjitha; Smith, Kathleen M.; Helfrich, Yolanda; Voorhees, John J.; Maverakis, Emanual; Modlin, Robert L.; Kahlenberg, J. Michelle; Scott, Victoria E.; Gudjonsson, Johann E.
Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
IF11.2
2022-02-0110
OAAI
Tsoi, Lam C.; Patrick, Matthew T.; Shuai, Shao; Sarkar, Mrinal K.; Chi, Sunyi; Ruffino, Bethany; Billi, Allison C.; Xing, Xianying; Uppala, Ranjitha; Zang, Cheng; Fullmer, Joseph; He, Zhi; Maverakis, Emanual; Mehta, Nehal N.; White, Bethany E. Perez; Getsios, Spiro; Helfrich, Yolanda; Voorhees, John J.; Kahlenberg, J. Michelle; Weidinger, Stephan; Gudjonsson, Johann E.
IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses

IRAK2在促进表皮炎症反应的前馈放大中具有关键作用

JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2021-10-0111
OAAI
Shao, Shuai; Tsoi, Lam C.; Swindell, William R.; Chen, Jiaoling; Uppala, Ranjitha; Billi, Allison C.; Xing, Xianying; Zeng, Chang; Sarkar, Mrinal K.; Wasikowski, Rachael; Jiang, Yanyun; Kirma, Joseph; Sun, Jingru; Plazyo, Olesya; Wang, Gang; Harms, Paul W.; Voorhees, John J.; Ward, Nicole L.; Ma, Feiyang; Pellegrini, Matteo; Merleev, Alexander; White, Bethany E. Perez; Modlin, Robert L.; Andersen, Bogi; Maverakis, Emanual; Weidinger, Stephan; Kahlenberg, J. Michelle; Gudjonsson, Johann E.
KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2020-05-1138
OA
Billi, Allison C.; Ludwig, Jessica E.; Fritz, Yi; Rozic, Richard; Swindell, William R.; Tsoi, Lam C.; Gruzska, Dennis; Abdollahi-Roodsaz, Shahla; Xing, Xianying; Diaconu, Doina; Uppala, Ranjitha; Camhi, Maya, I; Klenotic, Philip A.; Sarkar, Mrinal K.; Husni, M. Elaine; Scher, Jose U.; McDonald, Christine; Kahlenberg, J. Michelle; Midura, Ronald J.; Gudjonsson, Johann E.; Ward, Nicole L.
Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
IF11.2
2020-05-01136
OAAI
Tsoi, Lam C.; Rodriguez, Elke; Stoelzl, Dora; Wehkamp, Ulrike; Sun, Jingru; Gerdes, Sascha; Sarkar, Mrinal K.; Huebenthal, Matthias; Zeng, Chang; Uppala, Ranjitha; Xing, Xianying; Thielking, Frederieke; Billi, Allison C.; Swindell, William R.; Shefler, Alanna; Chen, Jiahan; Patrick, Matthew T.; Harms, Paul W.; Kahlenberg, J. Michelle; White, Bethany E. Perez; Maverakis, Emanual; Gudjonsson, Johann E.; Weidinger, Stephan
IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2019-09-25102
OAAI
Shao, Shuai; Tsoi, Lam C.; Sarkar, Mrinal K.; Xing, Xianying; Xue, Ke; Uppala, Ranjitha; Berthier, Celine C.; Zeng, Chang; Patrick, Matthew; Billi, Allison C.; Fullmer, Joseph; Beamer, Maria A.; Perez-White, Bethany; Getsios, Spiro; Schuler, Andrew; Voorhees, John J.; Choi, Sung; Harms, Paul; Kahlenberg, J. Michelle; Gudjonsson, Johann E.
Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis
JOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
2019-07-01324
OAAI
Tsoi, Lam C.; Rodriguez, Elke; Degenhardt, Frauke; Baurecht, Hansjoerg; Wehkamp, Ulrike; Volks, Natalie; Szymczak, Silke; Swindell, William R.; Sarkar, Mrinal K.; Raja, Kalpana; Shao, Shuai; Patrick, Matthew; Gao, Yilin; Uppala, Ranjitha; White, Bethany E. Perez; Getsios, Spiro; Harms, Paul W.; Maverakis, Emanual; Elder, James T.; Franke, Andre; Gudjonsson, Johann E.; Weidinger, Stephan
The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity
JCI INSIGHT
IF6.1
2019-04-1850
OA
Billi, Allison C.; Gharaee-Kermani, Mehrnaz; Fullmer, Joseph; Tsoi, Lam C.; Hill, Brett D.; Gruszka, Dennis; Ludwig, Jessica; Xing, Xianying; Estadt, Shannon; Wolf, Sonya J.; Rizvi, Syed Monem; Berthier, Celine C.; Hodgin, Jeffrey B.; Reamer, Maria A.; Sarkar, Mrinal K.; Liang, Yun; Uppala, Ranjitha; Shao, Shuai; Zeng, Chang; Harms, Paul W.; Verhaegen, Monique E.; Voorhees, John J.; Wen, Fei; Ward, Nicole L.; Dlugosz, Andrzej A.; Kahlenberg, J. Michelle; Gudjonsson, Johann E.

研究方向

暂未获取到该数据
J
Jóhann E. Guðjónsson
H 指数:80论文数:597被引数:2.7万
L
Lam C. Tsoi
H 指数:63论文数:414被引数:1.3万
M
Mrinal K. Sarkar
H 指数:35论文数:117被引数:4,145
J
J. Michelle Kahlenberg
H 指数:50论文数:243被引数:8,514
X
Xianying Xing
H 指数:44论文数:163被引数:6,069
A
Allison C. Billi
H 指数:33论文数:166被引数:4,208
M
Matthew T. Patrick
H 指数:26论文数:115被引数:2,961
E
Emanual Maverakis
H 指数:54论文数:481被引数:1.2万
B
Bethany E. Perez White
H 指数:20论文数:113被引数:2,640
P
Paul W. Harms
H 指数:52论文数:312被引数:9,331