Zhenzhen Zhan

Liaoning University

H指数:20

被引数:1,872

个人简介

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工作经历

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荣誉奖项

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RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

RNA结合蛋白RBM25靶向GTP酶Rab22a的mRNA稳定性以限制病毒进入和感染

Advanced Science

IF14.1

2026-06-160

Design, synthesis and biological evaluation of selective inhibitors against the L858R/T790M/C797S mutant EGFR kinase based on the scaffold of brigatinib

基于brigatinib骨架的设计、合成及选择性抑制L858R/T790M/C797S突变EGFR激酶的生物活性评价

European Journal of Medicinal Chemistry

IF5.9

2026-05-010

PRE

Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration

RBM22的恢复克服了心肌细胞增殖在心脏再生中的转录和表观遗传障碍

Nature Communications

IF15.7

2026-03-090

OAAI

Correction: Targeting KAT8 alleviates self-RNA-driven skin inflammation by modulating histone H4 lysine 16 acetylation in psoriasis

更正：靶向KAT8通过调节银屑病中组蛋白H4赖氨酸16的乙酰化，缓解自RNA驱动的皮肤炎症。

cell death & differentiation

IF0

2026-01-140

OAAI

Targeting KAT8 alleviates self-RNA-driven skin inflammation by modulating histone H4 lysine 16 acetylation in psoriasis

靶向KAT8通过调节银屑病中组蛋白H4赖氨酸16的乙酰化，缓解自RNA驱动的皮肤炎症。

cell death and differentiation

IF0

2025-07-210

PRE

Design, synthesis and biological evaluation of imine-containing inhibitors against the triple-mutant EGFR kinases based on the scaffold of osimertinib

基于osimertinib骨架的三突变EGFR激酶的亚胺类抑制剂的分子设计、合成及生物活性评价

BIOORGANIC CHEMISTRY

IF4.7

2025-06-010

PRE

Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis

磷酸酶PHLPP1是一种肺泡巨噬细胞内源的转录调控点，控制着肺纤维化。

CELL REPORTS

IF6.9

2025-03-010

OAAI

Establishment and validation of a predictive model of immune tolerance after pediatric liver transplantation: a multicenter cohort study

INTERNATIONAL JOURNAL OF SURGERY

IF10.1

2024-09-010

OAAI

Targeting NPM1 Epigenetically Promotes Postinfarction Cardiac Repair by Reprogramming Reparative Macrophage Metabolism

CIRCULATION

IF38.6

2024-06-189

OAAI

IRG1 prevents excessive inflammatory responses and cardiac dysfunction after myocardial injury

BIOCHEMICAL PHARMACOLOGY

IF5.6

2023-07-0115

PRE

Targeting KAT2A inhibits inflammatory macrophage activation and rheumatoid arthritis through epigenetic and metabolic reprogramming

靶向KAT2A通过表观遗传和代谢重编程抑制炎性巨噬细胞活化和类风湿关节炎

MEDCOMM

IF10.7

2023-06-1110

Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription

CELL DEATH AND DIFFERENTIATION

IF15.4

2023-03-1312

Murine neonatal cardiac B cells promote cardiomyocyte proliferation and heart regeneration

NPJ REGENERATIVE MEDICINE

IF6.5

2023-02-1116

Hair Derived Microneedle Patches for Both Diabetic Foot Ulcer Prevention and Healing

ACS BIOMATERIALS SCIENCE & ENGINEERING

IF5.5

2022-12-2311

PRE

Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2022-12-0818

OAAI

Single-cell transcriptome atlas reveals protective characteristics of COVID-19 mRNA vaccine

JOURNAL OF MEDICAL VIROLOGY

IF4.6

2022-10-017

PHLPP1 deficiency ameliorates cardiomyocyte death and cardiac dysfunction through inhibiting Mcl-1 degradation

CELLULAR SIGNALLING

IF3.7

2022-04-0110

PRE

Phosphatase PPM1L prevents excessive inflammatory responses and cardiac dysfunction after myocardial infarction by inhibiting IKKβ activation (vol 203, pg 1338, 2019)

JOURNAL OF IMMUNOLOGY

IF3.4

2020-03-010

OAAI

Phosphatase PPM1L Prevents Excessive Inflammatory Responses and Cardiac Dysfunction after Myocardial Infarction by Inhibiting IKKβ Activation

JOURNAL OF IMMUNOLOGY

IF3.4

2019-09-0110

OAAI

MicroRNA-21 prevents excessive inflammation and cardiac dysfunction after myocardial infarction through targeting KBTBD7

CELL DEATH & DISEASE

IF9.6

2018-07-10140

OAAI

Zhenzhen Zhan

个人简介

教育背景

工作经历

荣誉奖项

研究方向