logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
P

Petar Pop-Damkov

AstraZeneca
H指数:9
被引数:813

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

The application of mechanistic absorption, distribution, metabolism and excretion studies and physiologically-based pharmacokinetic modeling in the discovery of the next-generation oral selective estrogen receptor degrader camizestrant to achieve an acceptable human pharmacokinetic profile

基于机制性的吸收、分布、代谢和排泄研究以及生理药代动力学模型的应用，在下一代口服选择性雌激素受体降解剂camizestrant的发现中，以实现可接受的人类药代动力学特征。

Drug Metabolism and Disposition
IF4
2025-06-190
OA
Eric T. Gangl; Roshini Markandu; Pradeep Sharma; Andy Sykes; Petar Pop-Damkov; Ujjal Sarkar; Linda Andersson; Pablo Morentin-Gutierrez; James S. Scott; Adrian J. Fretland; Teresa Klinowska; Dermot F. McGinnity
Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase

通过口服A-T突变酶抑制剂AZD1390（醛氧化酶底物）实现人脑暴露。

Drug Metabolism and Disposition
IF4
2025-06-030
PRE
Nicola Colclough; Alexandra L. Orton; Scott Martin; Martin Wild; Venkatesh Pilla Reddy; Eva Lenz; Roshini Markandu; Joanne Wilson; Chunling Fan; Julian Potter; David Dai; Christina Chan; Jennie Roberts; Aixiang Xue; Petar Pop-Damkov; Andy Sykes; Barry Jones; Thomas A. Hunt; Kurt G. Pike; Dermot F. McGinnity
Discovery of (2R,4R)-4-((S)-2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-11-210
PRE
Mlynarski, Scott N.; Aquila, Brian M.; Cantin, Susan; Cook, Steve; Doshi, Aatman; Finlay, M. Raymond V.; Gangl, Eric T.; Grebe, Tyler; Gu, Chungang; Kawatkar, Sameer P.; Petersen, Jens; Pop-Damkov, Petar; Schuller, Alwin G.; Shao, Wenlin; Shields, Jason D.; Simpson, Iain; Tavakoli, Siavash; Tentarelli, Sharon; Throner, Scott; Wang, Haixia; Wang, Jianyan; Wu, Dedong; Ye, Qing
Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-03-134
OA
Doshi, Aatman S.; Cantin, Susan; Hernandez, Marylens; Srinivasan, Srimathi; Tentarelli, Sharon; Griffin, Matthew; Wang, Yanjun; Pop-Damkov, Petar; Prickett, Laura B.; Kankkonen, Cecilia; Shen, Minhui; Martin, Maryann San; Wu, Song; Castaldi, M. Paola; Ghadially, Hormas; Varnes, Jeffrey; Gales, Sonya; Henry, David; Hoover, Clare; Mele, Deanna A.; Simpson, Iain; Gangl, Eric T.; Mlynarski, Scott N.; Finlay, M. Raymond V.; Drew, Lisa; Fawell, Stephen E.; Shao, Wenlin; Schuller, Alwin G.
Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy
COMMUNICATIONS BIOLOGY
IF5.1
2021-01-2567
OAAI
Patterson, Claire M.; Balachander, Srividya B.; Grant, Iain; Pop-Damkov, Petar; Kelly, Brian; McCoull, William; Parker, Jeremy; Giannis, Michael; Hill, Kathryn J.; Gibbons, Francis D.; Hennessy, Edward J.; Kemmitt, Paul; Harmer, Alexander R.; Gales, Sonya; Purbrick, Stuart; Redmond, Sean; Skinner, Matthew; Graham, Lorraine; Secrist, J. Paul; Schuller, Alwin G.; Wen, Shenghua; Adam, Ammar; Reimer, Corinne; Cidado, Justin; Wild, Martin; Gangl, Eric; Fawell, Stephen E.; Saeh, Jamal; Davies, Barry R.; Owen, David J.; Ashford, Marianne B.
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology (vol 97, pg 234, 2019)
NATURE BIOMEDICAL ENGINEERING
IF26.6
2020-02-125
OAAI
Chou, David B.; Frismantas, Viktoras; Milton, Yuka; David, Rhiannon; Pop-Damkov, Petar; Ferguson, Douglas; MacDonald, Alexander; Bolukbasi, Ozge Vargel; Joyce, Cailin E.; Teixeira, Liliana S. Moreira; Rech, Arianna; Jiang, Amanda; Calamari, Elizabeth; Jalili-Firoozinezhad, Sasan; Furlong, Brooke A.; O'Sullivan, Lucy R.; Ng, Carlos F.; Choe, Youngjae; Marquez, Susan; Myers, Kasiani C.; Weinberg, Olga K.; Hasserjian, Robert P.; Novak, Richard; Levy, Oren; Prantil-Baun, Rachelle; Novina, Carl D.; Shimamura, Akiko; Ewart, Lorna; Ingber, Donald E.
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology
NATURE BIOMEDICAL ENGINEERING
IF26.6
2020-01-27186
OAAI
Chou, David B.; Frismantas, Viktoras; Milton, Yuka; David, Rhiannon; Pop-Damkov, Petar; Ferguson, Douglas; MacDonald, Alexander; Bolukbasi, Ozge Vargel; Joyce, Cailin E.; Teixeira, Liliana S. Moreira; Rech, Arianna; Jiang, Amanda; Calamari, Elizabeth; Jalili-Firoozinezhad, Sasan; Furlong, Brooke A.; O'Sullivan, Lucy R.; Ng, Carlos F.; Choe, Youngjae; Marquez, Susan; Myers, Kasiani C.; Weinberg, Olga K.; Hasserjian, Robert P.; Novak, Richard; Levy, Oren; Prantil-Baun, Rachelle; Novina, Carl D.; Shimamura, Akiko; Ewart, Lorna; Ingber, Donald E.

研究方向

暂未获取到该数据
E
Eric T. Gangl
H 指数:22论文数:161被引数:2,091
A
Alwin G. Schuller
H 指数:37论文数:267被引数:5,361
S
Scott N. Mlynarski
H 指数:9论文数:75被引数:1,178
R
Roshini Markandu
H 指数:5论文数:16被引数:71
S
Sharon Tentarelli
H 指数:12论文数:74被引数:1,090
M
M. Raymond V. Finlay
H 指数:25论文数:133被引数:5,731
A
Andy Sykes
H 指数:11论文数:45被引数:370
D
Dermot F. McGinnity
H 指数:27论文数:69被引数:3,130
A
Aixiang Xue
H 指数:5论文数:22被引数:102
L
Lorna Ewart
H 指数:31论文数:114被引数:3,878