Zsolt Sebestyén - Publications, H-index & Citations

Zsolt Sebestyén

university utrecht

27H指数

95论文数

2.6K被引数

收录论文 40

发表时间

Author Correction: Engineering anti-BCMA CAR T cells for enhancing myeloma killing efficacy via apoptosis regulation 作者更正：通过凋亡调控增强骨髓瘤杀伤效果的BCMA CAR T细胞工程

Nature Communications

IF15.7

2026-04-13

OAAI

Thomas Kimman; Marta Cuenca; Ralph G. Tieland; Dedeke Rockx-Brouwer; Jasmijn Janssen; Benjamin Motais; Anne Slomp; Corine Pleijte; Sabine Heijhuurs; Angelo D. Meringa; Wendy Boschloo; Douwe M. T. Bosma; Sanne Kroos; Vania lo Presti; Joost P. G. Sluijter; Stefan Nierkens; Niels Bovenschen; Jürgen Kuball; Alain van Mil; Monique C. Minnema; Zsolt Sebestyén; Victor Peperzak

Current capacity and gaps in viral vector manufacturing: a survey of centers associated with CTIWP of EBMT, NXTGEN-hightech, DARE-NL, T2EVOLVE, and GoCART coalition 病毒载体生产方面的当前产能与差距：对EBMT、NXTGEN-hightech、DARE-NL、T2EVOLVE和GoCART联盟相关中心的调查

Bone Marrow Transplantation

IF5.2

2025-12-17

PREAI

Ganesh Ramesh; Zsolt Sebestyen; Anil Kumar Deshantri; Simone Punt; Emma Martinez Sanchez; Jesus Fernandez-Sojo; Sergi Querol; Michael Hudecek; Carmen Sanges; Ruud Das; Aiko Ballardini; Cristina Eguizabal; Dirk Geerts; Ardeshir Ghavamzadeh; Virginia Escamilla Gómez; Manel Juan; Thomas Stauffer Larsen; Petr Lesný; Daniel Lysák; Mirko Müller; Unai Perpiñá; Sofieke de Wilde; Florent Malard; Jorinde Hoogenboom; Jarl Mooyaart; Annalisa Ruggeri; Trudy Straetemans; Jurgen Kuball

A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma 一项纵向单细胞图谱研究，用于预测多发性骨髓瘤中BCMA靶向CAR T细胞疗法后的结局和毒性。

Cancer Cell

IF44.5

2025-12-04

OAAI

Michael Rade; David Fandrei; Markus Kreuz; Sabine Seiffert; Anja Grahnert; Maik Friedrich; Thomas Wiemers; Patrick Born; Luise Fischer; Heike Weidner; Lorenz C. Hofbauer; Ronny Baber; Song Yau Wang; Enrica Bach; Sandra Hoffmann; Jonathan Scolnick; Mirco Friedrich; Farid Keramati; Peter Brazda; Zsolt Sebestyen

Unleashing Vδ2+ γδTILs in Glioblastoma: Overcoming the Maze of Tumor Evasion 在胶质母细胞瘤中释放Vδ2+ γδTILs：克服肿瘤逃逸的迷宫

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Nicolasen, Mara J. T.; Gatti, Lucrezia C. D. E.; Brazda, Peter; Botas, Marta; Celades, Laia Gasull; Zawal, Daniel; Cleven, Astrid; Sebestyen, Zsolt; Robe, Pierre A.; Beringer, Dennis X.; Kuball, Jurgen

Modeling Pediatric DMG in Human BrOs (Brainstem-regionalized Organoids) Dissects Tumour-Microglia-Immune Crosstalk and CAR T Cell Dysfunction 在人类脑干区域性类器官（Human BrOs）中模拟儿童弥漫性中脑胶质瘤（Pediatric DMG），解析了肿瘤-小胶质细胞-免疫互作以及CAR T细胞功能障碍。

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Bessler, Nils; Wezenaar, Amber K. L.; Ariese, Hendrikus C. R.; Honhoff, Celina; Wehrens, Ellen J.; Dommann, Noelle; Moreno, Cristian Ruiz; Van Den Broek, Thijs; Collot, Raphael V. U.; Kloosterman, Daan J.; Keramati, Farid; Roosen, Mieke; De Blank, Sam; Van Vliet, Esmee; Roman, Mario Barrera; Gatti, Lucrezia C. D. E.; Erturk, Ali; Kuball, Jurgen; Sebestyen, Zsolt; Kool, Marcel; Patrizi, Sara; Miele, Evelina; Kunkele, Annette; Kranendonk, Mariette E. G.; Cornel, Annelisa M.; Nierkens, Stefan; Mayer, Christian; Stunnenberg, Hendrik G.; Alemany, Anna; Alieva, Maria; Rios, Anne C.

Design specifications for biomedical virtual twins in engineered adoptive cellular immunotherapies 工程化嵌合细胞免疫疗法中生物医学虚拟双胞胎的设计规范

npj Digital Medicine

IF15.1

2025-08-01

OAAI

Ulrike Weirauch; Markus Kreuz; Colin Birkenbihl; Miriam Alb; Maria Quaranta; Laurence Calzone; Sophia Orozco-Ruiz; Stefanie Binder; Luise Fischer; Solène Clavreul; Morine Maguri; Maximilian Ferle; Michael Rade; Guillaume Azarias; Jay R. Hydren; Jakub Jamarik; Daniel Schwarz; Zsolt Sebestyen; Jurgen Kuball; Georg Popp; Chloé Antoine; Manon Knockaert; Clara T. Schoeder; David Fandrei; Carmen Sanges; Vaclovas Radvilas; Nico Gagelmann; Markus Rückert; Olaf Penack; Stephan Fricke; Andreas Schmidt; Carol Ward; Carl Steinbeisser; Jean-Marc Van Gyseghem; Anna Niarakis; Laurent Garderet; Michael Hudecek; Thomas Neumuth; Uwe Platzbecker; Ulrike Köhl; Regina Demlova; Andreas Kremer; Stefan Franke; Holger Fröhlich; Maximilian Merz; Kristin Reiche

Mapping T cell dynamics to molecular profiles through behavior-guided transcriptomics 通过行为引导转录组学将T细胞动态映射到分子谱中

NATURE PROTOCOLS

IF16

2025-02-10

PREAI

Wezenaar, A. K. L.; Pandey, U.; Keramati, F.; Hernandez-Roca, M.; Brazda, P.; Roman, M. Barrera; Cleven, A.; Karaiskaki, F.; Aarts-Riemens, T.; de Blank, S.; Hernandez-Lopez, P.; Heijhuurs, S.; Alemany, A.; Kuball, J.; Sebestyen, Z.; Dekkers, J. F.; Stunnenberg, H. G.; Alieva, M.

Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2024-04-05

OAAI

Lo Presti, Vania; Meringa, Angelo; Dunnebach, Ester; van Velzen, Alice; Moreira, Aida Valera; Stam, Ronald W.; Kotecha, Rishi S.; Krippner-Heidenreich, Anja; Heidenreich, Olaf T.; Plantinga, Maud; Cornel, Annelisa; Sebestyen, Zsolt; Kuball, Jurgen; van Til, Niek P.; Nierkens, S.

BEHAV3D: a 3D live imaging platform for comprehensive analysis of engineered T cell behavior and tumor response BEHAV3D: 一个3D实时成像平台，用于工程T细胞行为和肿瘤反应的综合分析

NATURE PROTOCOLS

IF16

2024-03-19

PREAI

Alieva, Maria; Roman, Mario Barrera; de Blank, Sam; Petcu, Diana; Zeeman, Amber L.; Dautzenberg, Noel M. M.; Cornel, Annelisa M.; van de Ven, Cesca; Pieters, Rob; den Boer, Monique L.; Nierkens, Stefan; Calkoen, Friso G. J.; Clevers, Hans; Kuball, Juergen; Sebestyen, Zsolt; Wehrens, Ellen J.; Dekkers, Johanna F.; Rios, Anne C.

Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells 癌症代谢组和应激抗原的双重靶向影响工程化T细胞的转录组异质性和功效

NATURE IMMUNOLOGY

IF27.6

2023-11-27

PREAI

Hernandez-Lopez, Patricia; van Diest, Eline; Brazda, Peter; Heijhuurs, Sabine; Meringa, Angelo; van Heyningen, Lauren Hoorens; Riillo, Caterina; Schwenzel, Caroline; Zintchenko, Marina; Johanna, Inez; Nicolasen, Mara J. T.; Cleven, Astrid; Kluiver, Thomas A.; Millen, Rosemary; Zheng, Jiali; Karaiskaki, Froso; Straetemans, Trudy; Clevers, Hans; de Bree, Remco; Stunnenberg, Hendrik G.; Peng, Weng Chuan; Roodhart, Jeanine; Minguet, Susana; Sebestyen, Zsolt; Beringer, Dennis X.; Kuball, Jurgen

Strategies to improve γδTCRs engineered T-cell therapies for the treatment of solid malignancies

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-06-27

OAAI

Meringa, A. D.; Hernandez-Lopez, P.; Cleven, A.; de Witte, M.; Straetemans, T.; Kuball, J.; Beringer, D. X.; Sebestyen, Z.

Serpin B9 controls tumor cell killing by CAR T cells Serpin B9通过CAR T细胞控制肿瘤细胞杀伤

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2023-03-17

OAAI

Kimman, Thomas; Slomp, Anne; Martens, Anne; Grabherr, Sarah; Li, Shuang; van Diest, Eline; Meeldijk, Jan; Kuball, Jurgen; Minnema, Monique C.; Eldering, Eric; Bovenschen, Niels; Sebestyen, Zsolt; Peperzak, Victor

Uncovering the mode of action of engineered T cells in patient cancer organoids 揭示工程改造的T细胞在患者癌症类器官中的作用方式

NATURE BIOTECHNOLOGY

IF41.7

2022-07-25

OAAI

Dekkers, Johanna F.; Alieva, Maria; Cleven, Astrid; Keramati, Farid; Wezenaar, Amber K. L.; van Vliet, Esmee J.; Puschhof, Jens; Brazda, Peter; Johanna, Inez; Meringa, Angelo D.; Rebel, Heggert G.; Buchholz, Maj-Britt; Roman, Mario Barrera; Zeeman, Amber L.; de Blank, Sam; Fasci, Domenico; Geurts, Maarten H.; Cornel, Annelisa M.; Driehuis, Else; Millen, Rosemary; Straetemans, Trudy; Nicolasen, Mara J. T.; Aarts-Riemens, Tineke; Ariese, Hendrikus C. R.; Johnson, Hannah R.; van Ineveld, Ravian L.; Karaiskaki, Froso; Kopper, Oded; Bar-Ephraim, Yotam E.; Kretzschmar, Kai; Eggermont, Alexander M. M.; Nierkens, Stefan; Wehrens, Ellen J.; Stunnenberg, Henk G.; Clevers, Hans; Kuball, Jurgen; Sebestyen, Zsolt; Rios, Anne C.

γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-07-07

OAAI

Vyborova, Anna; Janssen, Anke; Gatti, Lucrezia; Karaiskaki, Froso; Yonika, Austin; van Dooremalen, Sanne; Sanders, Jasper; Beringer, Dennis X.; Straetemans, Trudy; Sebestyen, Zsolt; Kuball, Juergen

The Role of γδ T Cells as a Line of Defense in Viral Infections after Allogeneic Stem Cell Transplantation: Opportunities and Challenges

VIRUSES-BASEL

IF3.5

2022-01-10

OAAI

Janssen, Anke; van Diest, Eline; Vyborova, Anna; Schrier, Lenneke; Bruns, Anke; Sebestyen, Zsolt; Straetemans, Trudy; de Witte, Moniek; Kuball, Juergen

Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-10-25

OAAI

Johanna, Inez; Hernandez-Lopez, Patricia; Heijhuurs, Sabine; Scheper, Wouter; Bongiovanni, Laura; de Bruin, Alain; Beringer, Dennis X.; Oostvogels, Rimke; Straetemans, Trudy; Sebestyen, Zsolt; Kuball, Juergen

γ9δ2T cell diversity and the receptor interface with tumor cells Γ9δ2t细胞多样性和与肿瘤细胞的受体界面

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2020-08-04

OAAI

Vyborova, Anna; Beringer, Dennis X.; Fasci, Domenico; Karaiskaki, Froso; van Diest, Eline; Kramer, Lovro; de Haas, Aram; Sanders, Jasper; Janssen, Anke; Straetemans, Trudy; Olive, Daniel; Leusen, Jeanette; Boutin, Lola; Nedellec, Steven; Schwartz, Samantha L.; Wester, Michael J.; Lidke, Keith A.; Scotet, Emmanuel; Lidke, Diane S.; Heck, Albert, Jr.; Sebestyen, Zsolt; Kuball, Jurgen

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

JOURNAL OF LEUKOCYTE BIOLOGY

IF3.1

2020-02-05

OAAI

Johanna, Inez; Hernandez-Lopez, Patricia; Heijhuurs, Sabine; Bongiovanni, Laura; de Bruin, Alain; Beringer, Dennis; van Dooremalen, Sanne; Shultz, Leonard D.; Ishikawa, Fumihiko; Sebestyen, Zsolt; Straetemans, Trudy; Kuball, Jurgen

TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product

MOLECULAR THERAPY

IF12

2020-02-01

OAAI

Straetemans, Trudy; Janssen, Anke; Jansen, Koen; Doorn, Ruud; Aarts, Tineke; van Muyden, Anna D. D.; Simonis, Marieke; Bergboer, Judith; de Witte, Moniek; Sebestyen, Zsolt; Kuball, Jurgen

Identification of a tumor-specific allo-HLA-restricted γδTCR

BLOOD ADVANCES

IF7.1

2019-10-04

OAAI

Kierkels, G. J. J.; Scheper, W.; Meringa, A. D.; Johanna, I; Beringer, D. X.; Janssen, A.; Schiffler, M.; Aarts-Riemens, T.; Kramer, L.; Straetemans, T.; Heijhuurs, S.; Leusen, J. H. W.; San Jose, E.; Fuchs, K.; Griffioen, M.; Falkenburg, J. H.; Bongiovanni, L.; de Bruin, A.; Vargas-Diaz, D.; Altelaar, M.; Heck, A. J. R.; Shultz, L. D.; Ishikawa, F.; Nishimura, M., I; Sebestyen, Z.; Kuball, J.

研究方向