Jonathan M. Levy - Publications, H-index & Citations

Jonathan M. Levy

MIT and Harvard

24H指数

52论文数

1.0W被引数

收录论文 23

发表时间

In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder 体内碱基编辑纠正Zellweger谱系障碍小鼠模型的肝脏病理生理学和过氧化物酶体功能障碍

Nature Biomedical Engineering

IF26.6

2026-04-14

OAAI

Xin D. Gao; Maximiliano Presa; Jordyn E. Duby; Jennifer Ryan; Pierre-Alexandre Piec; Alvin Hsu; Samagya Banskota; Allen Yujie Jiang; Lingxiao Chen; Gregory A. Newby; Erminia Di Pietro; Jonathan M. Levy; Bradford H. Steele; Sarah Lecordier; Fangfei Qin; Ann B. Moser; Jun Xie; Guangping Gao; Nancy E. Braverman; Aamir R. Zuberi; Joseph G. Hacia; Cathleen M. Lutz; David R. Liu

Systematic empirical evaluation of individual base editing targets: Validating therapeutic in USH2A and of methods 对单个碱基编辑目标的系统性实证评估：验证在USH2A中的治疗方法和有效性

MOLECULAR THERAPY

IF12

2025-01-01

OAAI

Tachida, Yuki; Manian, Kannan, V; Butcher, Rossano; Levy, Jonathan M.; Pendse, Nachiket; Hennessey, Erin; Liu, David R.; Pierce, Eric A.; Liu, Qin; Comander, Jason

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput 以翻译后修饰为中心的碱基编辑器筛选以评估高通量的磷酸化位点功能

NATURE METHODS

IF32.1

2024-04-29

PREAI

Kennedy, Patrick H.; Sheikh, Amin Alborzian Deh; Balakar, Matthew; Jones, Alexander C.; Olive, Meagan E.; Hegde, Mudra; Matias, Maria I.; Pirete, Natan; Burt, Rajan; Levy, Jonathan; Little, Tamia; Hogan, Patrick G.; Liu, David R.; Doench, John G.; Newton, Alexandra C.; Gottschalk, Rachel A.; de Boer, Carl G.; Alarcon, Suzie; Newby, Gregory A.; Myers, Samuel A.

Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F

MOLECULAR THERAPY

IF12

2023-08-01

PREAI

Peters, Cole W.; Hanlon, Killian S.; Ivanchenko, Maryna; Zinn, Eric; Linarte, Elizabeth F.; Li, Yaqiao; Levy, Jonathan M.; Liu, David R.; Kleinstiver, Benjamin P.; Indzhykulian, Artur A.; Corey, David P.

Efficient prime editing in mouse brain, liver and heart with dual AAVs

NATURE BIOTECHNOLOGY

IF41.7

2023-05-04

OAAI

Davis, Jessie R.; Banskota, Samagya; Levy, Jonathan M.; Newby, Gregory A.; Wang, Xiao; Anzalone, Andrew V.; Nelson, Andrew T.; Chen, Peter J.; Hennes, Andrew D.; An, Meirui; Roh, Heejin; Randolph, Peyton B.; Musunuru, Kiran; Liu, David R.

Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors (Jul, 10.1038/s41551-022-00911-4, 2022)利用编码紧凑腺嘌呤碱基编辑器的大小优化的基因组，通过单个腺相关病毒进行有效的体内碱基编辑 (7月，10.1038/s41551-022-00911-4，2022)

NATURE BIOMEDICAL ENGINEERING

IF26.6

2022-08-05

OAAI

Davis, Jessie R.; Wang, Xiao; Witte, Isaac P.; Huang, Tony P.; Levy, Jonathan M.; Raguram, Aditya; Banskota, Samagya; Seidah, Nabil G.; Musunuru, Kiran; Liu, David R.

Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors 通过具有大小优化的编码紧凑腺嘌呤碱基编辑器的单个腺相关病毒进行有效的体内碱基编辑

NATURE BIOMEDICAL ENGINEERING

IF26.6

2022-07-28

104

OAAI

Davis, Jessie R.; Wang, Xiao; Witte, Isaac P.; Huang, Tony P.; Levy, Jonathan M.; Raguram, Aditya; Banskota, Samagya; Seidah, Nabil G.; Musunuru, Kiran; Liu, David R.

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing 通过双素数编辑对大DNA序列进行可编程的删除，替换，整合和反转

NATURE BIOTECHNOLOGY

IF41.7

2021-12-09

302

OAAI

Anzalone, Andrew, V; Gao, Xin D.; Podracky, Christopher J.; Nelson, Andrew T.; Koblan, Luke W.; Raguram, Aditya; Levy, Jonathan M.; Mercer, Jaron A. M.; Liu, David R.

In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2020-06-03

128

OAAI

Yeh, Wei-Hsi; Shubina-Oleinik, Olga; Levy, Jonathan M.; Pan, Bifeng; Newby, Gregory A.; Wornow, Michael; Burt, Rachel; Chen, Jonathan C.; Holt, Jeffrey R.; Liu, David R.

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses 通过腺相关病毒对小鼠的大脑，肝脏，视网膜，心脏和骨骼肌进行胞嘧啶和腺嘌呤碱基编辑

NATURE BIOMEDICAL ENGINEERING

IF26.6

2020-01-14

356

OAAI

Levy, Jonathan M.; Yeh, Wei-Hsi; Pendse, Nachiket; Davis, Jessie R.; Hennessey, Erin; Butcher, Rossano; Koblan, Luke W.; Comander, Jason; Liu, Qin; Liu, David R.

Continuous evolution of base editors with expanded target compatibility and improved activity (vol 37, pg 1070, 2019)

NATURE BIOTECHNOLOGY

IF41.7

2019-08-12

OAAI

Thuronyi, Benjamin W.; Koblan, Luke W.; Levy, Jonathan M.; Yeh, Wei-Hsi; Zheng, Christine; Newby, Gregory A.; Wilson, Christopher; Bhaumik, Mantu; Shubina-Oleinik, Olga; Holt, Jeffrey R.; Liu, David R.

Continuous evolution of base editors with expanded target compatibility and improved activity

NATURE BIOTECHNOLOGY

IF41.7

2019-07-22

269

OAAI

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction 通过表达优化和祖先重建来改善胞苷和腺嘌呤碱基编辑器

NATURE BIOTECHNOLOGY

IF41.7

2018-10-01

704

OAAI

Koblan, Luke W.; Doman, Jordan L.; Wilson, Christopher; Levy, Jonathan M.; Tay, Tristan; Newby, Gregory A.; Maianti, Juan Pablo; Raguram, Aditya; Liu, David R.

A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry

NATURE COMMUNICATIONS

IF15.7

2018-01-23

OAAI

Ullman, Julie C.; Yang, Jing; Sullivan, Michael; Bendor, Jacob; Levy, Jonathan; Pham, Ellen; Silm, Katlin; Seifikar, Helia; Sohal, Vikaas S.; Nicoll, Roger A.; Edwards, Robert H.

Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2 突触稳态需要GluA2的膜近端羧基尾

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-11-27

OAAI

Esselmann, Samantha G. Ancona; Diaz-Alonso, Javier; Levy, Jonathan M.; Bemben, Michael A.; Nicoll, Roger A.

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-06-19

OAAI

Diaz-Alonso, Javier; Sun, Yujiao J.; Granger, Adam J.; Levy, Jonathan M.; Blankenship, Sabine M.; Nicoll, Roger A.

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions

NATURE BIOTECHNOLOGY

IF41.7

2017-02-13

753

OAAI

Kim, Y. Bill; Komor, Alexis C.; Levy, Jonathan M.; Packer, Michael S.; Zhao, Kevin T.; Liu, David R.

PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-11-24

242

OAAI

Chen, Xiaobing; Levy, Jonathan M.; Hou, Austin; Winters, Christine; Azzam, Rita; Sousa, Alioscka A.; Leapman, Richard D.; Nicoll, Roger A.; Reese, Thomas S.

Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss

NEURON

IF15

2015-08-01

OAAI

Levy, Jonathan M.; Chen, Xiaobing; Reese, Thomas S.; Nicoll, Roger A.

piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning

DEVELOPMENTAL CELL

IF8.7

2008-02-01

223

OAAI

Schuldiner, Oren; Berdnik, Daniela; Levy, Jonathan Ma; Wu, Joy S.; Luginbuhl, David; Camille Gontang, Allison; Luo, Liqun

研究方向