David F. Wiemer - Publications, H-index & Citations

David F. Wiemer

university of iowa

44H指数

338论文数

6.3K被引数

收录论文 108

发表时间

Incorporation of an alpha-hydroxy substituent modulates activity of triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors 引入一个α-羟基取代基调节了三唑双膦酸盐基法尼基焦磷酸合酶抑制剂的活性

Bioorganic & Medicinal Chemistry

IF3

2026-03-15

OAAI

Md. Ayub Ali; Dan Feng; Staci L. Haney; David F. Wiemer; Sarah A. Holstein

Benzoic Acid Derivatives Improve Plasma Stability of Diester Butyrophilin Ligand Prodrugs 苯甲酸衍生物改善二酯类但酪蛋白配体前药的血浆稳定性

Journal of Medicinal Chemistry

IF6.8

2026-02-12

OAAI

Parker A. Kintigh; Umed Singh; Girija Pawge; Sidra Bashir; Chia-Hung Christine Hsiao; Andrew J. Wiemer; David F. Wiemer

Synthesis and evaluation of triazole-containing aryl/acyloxy prodrugs of a BTN3A1 ligand

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-04-01

PREAI

Singh, Umed; Pawge, Girija; Kintigh, Parker A.; Sarno, Joseph P.; Rani, Sarita; Hsiao, Chia-Hung Christine; Wiemer, Andrew J.; Wiemer, David F.

Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2025-02-01

PREAI

Ali, Md. Ayub; Maalouf, Mona A.; Feng, Dan; Rashid, Mamunur; Gehrke, Nathaniel R.; Chhonker, Yashpal S.; Murry, Daryl J.; Wiemer, David F.; Holstein, Sarah A.

Enhanced Plasma Stability and Potency of Aryl/Acyloxy Prodrugs of a BTN3A1 Ligand

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-09-25

PREAI

Singh, Umed; Pawge, Girija; Rani, Sarita; Hsiao, Chia-Hung Christine; Wiemer, David F.; Wiemer, Andrew J.

Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-11-07

OAAI

Singh, Umed; Pawge, Girija; Rani, Sarita; Hsiao, Chia-Hung Christine; Wiemer, Andrew J.; Wiemer, David F.

Synthesis and Metabolism of BTN3A1 Ligands: Studies on Diene Modifications to the Phosphoantigen Scaffold

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2022-01-27

OAAI

Harmon, Nyema M.; Poe, Michael M.; Huang, Xueting; Singh, Rohit; Foust, Benjamin J.; Hsiao, Chia-Hung Christine; Wiemer, David F.; Wiemer, Andrew J.

Synthesis of a Coumarin-Based Analogue of Schweinfurthin F

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2021-10-29

OAAI

Schroeder, Chloe M.; Dey, Patrick N.; Beutler, John A.; Wiemer, David F.

Impact of α-modifications on the activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-08-01

OAAI

Fairweather, Alisa E. R.; Goetz, Daniel B.; Schroeder, Chloe M.; Bhuiyan, Nazmul H.; Varney, Michelle L.; Wiemer, David F.; Holstein, Sarah A.

Synthesis and Metabolism of BTN3A1 Ligands: Studies on Modifications of the Allylic Alcohol

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2020-12-04

OAAI

Lentini, Nicholas A.; Schroeder, Chloe M.; Harmon, Nyema M.; Huang, Xueting; Schladetsch, Megan A.; Foust, Benjamin J.; Poe, Michael M.; Hsiao, Chia-Hung Christine; Wiemer, Andrew J.; Wiemer, David F.

Potent double prodrug forms of synthetic phosphoantigens

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-10-01

OAAI

Harmon, Nyema M.; Huang, Xueting; Schladetsch, Megan A.; Hsiao, Chia-Hung Christine; Wiemer, Andrew J.; Wiemer, David F.

Amides as bioisosteres of triazole-based geranylgeranyl diphosphate synthase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-08-01

OAAI

Goetz, Daniel B.; Varney, Michelle L.; Wiemer, David F.; Holstein, Sarah A.