Cynthia T. McMurray - Publications, H-index & Citations

Cynthia T. McMurray

lawrence berkeley national laboratory

51H指数

141论文数

9.5K被引数

收录论文 62

发表时间

Double strand breaks drive toxicity in a Huntington’s disease mouse model with or without somatic expansion 双链断裂在带有或不带有体细胞扩展的亨廷顿病小鼠模型中驱动毒性

Nature Communications

IF15.7

2026-05-06

OAAI

Aris A. Polyzos; Ana Cheong; Jung Hyun Yoo; Lana Blagec; Zachary D. Nagel; Cynthia T. McMurray

Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain

NATURE COMMUNICATIONS

IF15.7

2024-09-04

OAAI

Polyzos, Aris A.; Cheong, Ana; Yoo, Jung Hyun; Blagec, Lana; Toprani, Sneh M.; Nagel, Zachary D.; McMurray, Cynthia T.

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

494

OAAI

Trushina, E; Dyer, RB; Badger, JD; Ure, D; Eide, L; Tran, DD; Vrieze, BT; Legendre-Guillemin, V; McPherson, PS; Mandavilli, BS; Van Houten, B; Zeitlin, S; McNiven, M; Aebersold, R; Hayden, M; Parisi, JE; Seeberg, E; Dragatsis, I; Doyle, K; Bender, A; Chacko, C; McMurray, CT

Nuclease-deficient FEN-1 blocks rad51/BRCA1-mediated repair and causes trinucleotide repeat instability

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Spiro, C; McMurray, CT

An infrared spectral biomarker accurately predicts neurodegenerative disease class in the absence of overt symptoms

SCIENTIFIC REPORTS

IF3.9

2021-08-02

OAAI

Lovergne, Lila; Ghosh, Dhruba; Schuck, Renaud; Polyzos, Aris A.; Chen, Andrew D.; Martin, Michael C.; Barnard, Edward S.; Brown, James B.; McMurray, Cynthia T.

Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans

TOXICOLOGICAL SCIENCES

IF4.1

2019-08-19

OAAI

Sammi, Shreesh Raj; Foguth, Rachel M.; Nieves, Claudia Sofia; De Perre, Chloe; Wipf, Peter; McMurray, Cynthia T.; Lee, Linda S.; Cannon, Jason R.

Metabolic Reprogramming in Astrocytes Distinguishes Region-Specific Neuronal Susceptibility in Huntington Mice

CELL METABOLISM

IF30.9

2019-06-01

109

OAAI

Polyzos, Aris A.; Lee, Do Yup; Datta, Rupsa; Hauser, Meghan; Budworth, Helen; Holt, Amy; Mihalik, Stephanie; Goldschmidt, Pike; Frankel, Ken; Trego, Kelly; Bennett, Michael J.; Vockley, Jerry; Xu, Ke; Gratton, Enrico; McMurray, Cynthia T.

Folate deficiency drives mitotic missegregation of the human FRAXA locus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-03

OAAI

Bjerregaard, Victoria A.; Garribba, Lorenza; McMurray, Cynthia T.; Hickson, Ian D.; Liu, Ying

Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts

DNA REPAIR

IF2.7

2017-08-01

OAAI

Polyzos, Aris A.; McMurray, Cynthia T.

The chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's disease

MECHANISMS OF AGEING AND DEVELOPMENT

IF5.1

2017-01-01

OAAI

Polyzos, Aris A.; McMurray, Cynthia T.

Crosstalk between MSH2-MSH3 and pol β promotes trinucleotide repeat expansion during base excision repair

NATURE COMMUNICATIONS

IF15.7

2016-08-22

OAAI

Lai, Yanhao; Budworth, Helen; Beaver, Jill M.; Chan, Nelson L. S.; Zhang, Zunzhen; McMurray, Cynthia T.; Liu, Yuan

Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes

HUMAN MOLECULAR GENETICS

IF3.2

2016-02-21

OAAI

Polyzos, Aris; Holt, Amy; Brown, Christopher; Cosme, Celica; Wipf, Peter; Gomez-Marin, Alex; Castro, Mariadel R.; Ayala-Pena, Sylvette; McMurray, Cynthia T.

Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease

PLOS GENETICS

IF3.7

2015-08-06

145

OAAI

Budworth, Helen; Harris, Faye R.; Williams, Paul; Lee, Do Yup; Holt, Amy; Pahnke, Jens; Szczesny, Bartosz; Acevedo-Torres, Karina; Ayala-Pena, Sylvette; McMurray, Cynthia T.

Trinucleotide expansion in disease: Why is there a length threshold? (vol 26, pg 131, 2014)

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2015-02-01

PREAI

Lee, Do-Yup; McMurray, Cynthia T.

Trinucleotide expansion in disease: why is there a length threshold?

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2014-06-01

OAAI

Lee, Do-Yup; McMurray, Cynthia T.

Editorial overview: Molecular and genetic bases of disease: The double life of DNA

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2014-06-01

OAAI

McMurray, Cynthia T.; Vijg, Jan

Loss of caveolin-1 expression in knock-in mouse model of Huntington's disease suppresses pathophysiology in vivo

HUMAN MOLECULAR GENETICS

IF3.2

2013-09-10

OAAI

Trushina, Eugenia; Canaria, Christie A.; Lee, Do-Yup; McMurray, Cynthia T.

Bidirectional transcription of trinucleotide repeats: Roles for excision repair

DNA REPAIR

IF2.7

2013-08-01

OAAI

Budworth, Helen; McMurray, Cynthia T.

Comprehensive macromolecular conformations mapped by quantitative SAXS analyses

NATURE METHODS

IF32.1

2013-04-28

120

OAAI

Hura, Greg L.; Budworth, Helen; Dyer, Kevin N.; Rambo, Robert P.; Hammel, Michal; McMurray, Cynthia T.; Tainer, John A.

Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington's Disease

CELL REPORTS

IF6.9

2012-11-01

128

OAAI

Xun, Zhiyin; Rivera-Sanchez, Sulay; Ayala-Pena, Sylvette; Lim, James; Budworth, Helen; Skoda, Erin M.; Robbins, Paul D.; Niedernhofer, Laura J.; Wipf, Peter; McMurray, Cynthia T.

研究方向