Ian B. Seiple - Publications, H-index & Citations

Ian B. Seiple

University of California - San Francisco

29H指数

114论文数

4.9K被引数

收录论文 34

发表时间

Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome 基于结构的A族链阳性菌素设计及其与核糖体新生肽链出口通道结合的合成

European Journal of Medicinal Chemistry

IF5.9

2026-05-09

PREAI

Isabel J. Lee; Qi Li; Tushar Raskar; Jenna Pellegrino; Andrew K. Ecker; Sara Y. Howard; James S. Fraser; Ian B. Seiple

Initial leads to combat streptogramin resistance generated from X-ray fragment screening against VatD 通过针对VatD的X射线片段筛选获得的初始先导化合物，用于对抗链阳菌素耐药性。

Structure

IF4.3

2025-09-12

PREAI

Pooja Asthana; Sonya Lee; Christian M. MacDonald; Ian B. Seiple; James S. Fraser

Hybrid Antibiotics Targeting the Bacterial Ribosome 靶向细菌核糖体的杂合抗生素

ACS CENTRAL SCIENCE

IF10.4

2025-09-01

PREAI

Yeon, Seul Ki; Pellegrino, Jenna; Raskar, Tushar; Tran, Minh L. N.; Dandan, Mohamad; Guerin, Francois; Einsiedler, Manuel; Cattoir, Vincent; Fraser, James S.; Seiple, Ian B.

A Convergent Approach to Resorcinolic Macrolides to Expand Structural Diversity 一种收敛性合成策略用于扩大间苯二酚大环内酯的结构多样性

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2025-05-15

PREAI

Lombera, Jesus M. Madrigal; Feng, Xi; Shu, Xiaokun; Seiple, Ian B.

Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

ELIFE

IF0

2024-06-17

OAAI

Diaz, Roberto Efrain; Ecker, Andrew K.; Correy, Galen J.; Asthana, Pooja; Young, Iris D.; Faust, Bryan; Thompson, Michael C.; Seiple, Ian B.; Van Dyken, Steven; Locksley, Richard M.; Fraser, James S.

Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice

NATURE BIOTECHNOLOGY

IF41.7

2022-07-25

OAAI

Tolani, Bhairavi; Celli, Anna; Yao, Yanmin; Tan, Yong Zi; Fetter, Richard; Liem, Christina R.; de Smith, Adam J.; Vasanthakumar, Thamiya; Bisignano, Paola; Cotton, Adam D.; Seiple, Ian B.; Rubinstein, John L.; Jost, Marco; Weissman, Jonathan S.

Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-05-17

OAAI

Prasad, Neha K.; Seiple, Ian B.; Cirz, Ryan T.; Rosenberg, Oren S.

Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins

ACS CHEMICAL BIOLOGY

IF3.8

2022-04-28

PREAI

Gramespacher, Josef A.; Cotton, Adam D.; Burroughs, Paul W. W.; Seiple, Ian B.; Wells, James A.

Examining Gender Imbalance in Chemistry Authorship

ACS CHEMICAL BIOLOGY

IF3.8

2021-09-15

OAAI

Cotton, Adam D.; Seiple, Ian B.

Biotin as a Reactive Handle to Selectively Label Proteins and DNA with Small Molecules

ACS CHEMICAL BIOLOGY

IF3.8

2021-08-19

PREAI

Cotton, Adam D.; Wells, James A.; Seiple, Ian B.

Label-retention expansion microscopy

JOURNAL OF CELL BIOLOGY

IF6.4

2021-07-06

OAAI

Shi, Xiaoyu; Li, Qi; Dai, Zhipeng; Tran, Arthur A.; Feng, Siyu; Ramirez, Alejandro D.; Lin, Zixi; Wang, Xiaomeng; Chow, Tracy T.; Chen, Jiapei; Kumar, Dhivya; McColloch, Andrew R.; Reiter, Jeremy F.; Huang, Eric J.; Seiple, Ian B.; Huang, Bo

Polarized endosome dynamics engage cytoplasmic Par-3 that recruits dynein during asymmetric cell division

SCIENCE ADVANCES

IF12.5

2021-06-11

OAAI

Zhao, Xiang; Garcia, Jason Q.; Tong, Kai; Chen, Xingye; Yang, Bin; Li, Qi; Dai, Zhipeng; Shi, Xiaoyu; Seiple, Ian B.; Huang, Bo; Guo, Su

Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2021-04-01

OAAI

Cai, Lingchao; Seiple, Ian B.; Li, Qi