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H

Hiroyuki Konno

menofia university

55H指数
654论文数
1.6W被引数
收录论文 125
发表时间
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Multitarget anti-inflammatory celecoxib-based hybrids: Design, synthesis, and mechanistic evaluation of COX-2/5-LOX/sEH modulation with liposomal formulation, ADMET profiling, and molecular dynamics studies基于塞来昔布的多靶点抗炎杂合体：脂质体制剂、ADMET表征及分子动力学研究对COX-2/5-LOX/sEH调节的设计、合成与机制评价
errJournal of Molecular Structure
IF4.7
err2026-08-01
err0
PREAI
errSoltan, Osama M.; Abdelrahman, Kamal S.; Ouf, Abdelsalam Mohamed Abdelsalam; Amin, Mohammed M.; Abdelbaset, Mahmoud S.; Hegazy, Mohamed E.; El-Rashedy, Ahmed A.; Hamdi, Abdelrahman; Elafify, Mohamed S.; Ueda, Motoki; Asayama, Shoichiro; Narumi, Atsushi; Konno, Hiroyuki; Bass, Amr K. A.
err分享
err收藏
Design, Synthesis, and Biological Evaluation of Tetrahydroindazole-Based Sulfonamides as Potential Multi-Target Anti-Inflammatory Agents基于四氢吲唑的磺酰胺类化合物的设计、合成及生物活性评价：作为潜在的多靶点抗炎药物
errPharmaceuticals
IF4.8
err2026-05-29
err0
errOAAI
errMohammed A. I. Elbastawesy; Ahmed H. Abdelhafez; Abdullah Yahya Abdullah Alzahrani; Bandar A. Alyami; Hanyu Ling; Mahmoud S. Abdelbaset; Ahmed A. Gaber; Bahaa G. M. Youssif; Stefan Brase; Hiroyuki Konno
err分享
err收藏
Design and development of 1,5-diarylpyrazole-based multitarget-directed ligands as dual COX-2/HDAC6 inhibitors for Alzheimer’s disease therapy: Molecular dynamics and experimental insights基于1,5-二芳基吡唑的双靶点导向配体作为COX-2/HDAC6双重抑制剂的阿尔茨海默病疗法：分子动力学与实验见解
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-03-02
err0
PREAI
errKamal S. Abdelrahman; Osama M. Soltan; Hend E. Abo Mansour; Amany E. Nofal; Eman A. Eissa; Heba Rady Salem; Marwa M. Mahfouz; Samar A. El-Adawy; Ghada S.A. Ewies; Abdelrahman Hamdi; Mostafa M. Elbadawi; Ahmed H.A. Abusabaa; Ahmed A. El-Rashedy; Hiroyuki Konno; Amr K.A. Bass
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err收藏
Structural revision of burkholdine-1215, a cyclic octapeptide isolated from Burkholderia从Burkholderia中分离得到的环状八肽burkholdine-1215的结构修订。
errNatural Product Research
IF1.6
err2025-12-01
err0
PREAI
errKainuma, Rin; Sasaki, Sota; Yano, Shigekazu; Konno, Hiroyuki
err分享
err收藏
Design, synthesis, and biological evaluation of novel 1,5-diarylpyrazole carboxamides with dual inhibition of EGFR and COX-2 for the treatment of cancer and inflammatory diseases新型1,5-二芳基吡唑甲酰胺的设计、合成及其对EGFR和COX-2的双靶点抑制生物活性评价，用于癌症和炎症性疾病的治疗
errBioorganic & Medicinal Chemistry Letters
IF2.2
err2025-09-20
err0
PREAI
errOsama M. Soltan; Salah A. Abdel-Aziz; Kamal S. Abdelrahman; Atsushi Narumi; Mohamed Abdel-Aziz; Mai E. Shoman; Hiroyuki Konno
err分享
err收藏
Microwave-Assisted Oxidation with Catalyzed by N-Hydroxyphtalimide Derivatives微波辅助的N-羟基邻苯二甲酰亚胺衍生物催化的氧化反应
errCHEMISTRYSELECT
IF2
err2025-09-08
err0
errOAAI
errLing, Hanyu; Sano, Hinata; Doi, Kazuma; Konno, Hiroyuki
err分享
err收藏
Crystal structure of GH71 α-1,3-glucanase Agn1p from Schizosaccharomyces pombe: an enzyme regulating cell division in fission yeast来自裂殖酵母Schizosaccharomyces pombe的GH71 α-1,3-葡聚糖酶Agn1p的晶体结构：一种调控裂殖酵母细胞分裂的酶
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2025-06-01
err0
PREAI
errHoraguchi, Yui; Saitoh, Honoka; Konno, Hiroyuki; Makabe, Koki; Yano, Shigekazu
err分享
err收藏
Antifungal activity of GH64 (3-1,3-glucanase from the gram-negative bacterium Flavobacterium johnsoniaeGH64（来自革兰氏阴性菌Flavobacterium johnsoniae的3-1,3-葡聚糖酶）的抗真菌活性
errBIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
IF3.8
err2025-06-01
err0
PREAI
errWatanabe, Aoi; Yokomichi, Moe; Suyotha, Wasana; Takahata, Yasuyuki; Konno, Hiroyuki; Makabe, Koki; Yano, Shigekazu
err分享
err收藏
Therapeutic effect of curcumin derivative GT863 on prion-infected mice
errSCIENTIFIC REPORTS
IF3.9
err2025-02-14
err0
errOAAI
errTeruya, Kenta; Oguma, Ayumi; Okuda, Michiaki; Iwabuchi, Sara; Konno, Hiroyuki; Arai, Hiroyuki; Kudo, Yukitsuka; Sugimoto, Hachiro; Doh-ura, Katsumi
err分享
err收藏
Secretoglobin 3A2 peptides have therapeutic potential for allergic airway inflammation
errLIFE SCIENCES
IF5.1
err2024-12-01
err0
PREAI
errKurotani, Reiko; Sato, Yui; Okawara, Ayaka; Fukuda, Nichika; Hada, Kengo; Sakahara, Satoshi; Takakura, Kei; Abe, Hiroyuki; Konno, Hiroyuki; Kimura, Shioko
err分享
err收藏
Redesign of a thioflavin-T-binding protein with a flat β-sheet to evaluate a thioflavin-T-derived photocatalyst with enhanced affinity重新设计具有平坦 β-折叠的硫磺素T结合蛋白，以评估具有增强亲和力的硫磺素T衍生的光催化剂
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2024-06-01
err1
PREAI
errMiura, Yuina; Namioka, Sae; Iwai, Atsushi; Yoshida, Norio; Konno, Hiroyuki; Sohma, Youhei; Kanai, Motomu; Makabe, Koki
err分享
err收藏
SpyTag Peptide with Alkoxyl Aspartic Acids for pH-Dependent Activation of the SpyCatcher/Tag System
errBIOCONJUGATE CHEMISTRY
IF3.9
err2024-04-26
err1
PREAI
errChe, Sonji; Konno, Hiroyuki; Makabe, Koki
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err收藏
Synthesis and Structural Revision of the Cyclic Hexapeptide Dimers Antatollamides A and B
errORGANIC LETTERS
IF5
err2024-04-17
err2
PREAI
errLi, Yitong; Takamatsu, Keigo; Aota, Taichi; Konno, Hiroyuki
err分享
err收藏
α-1,3-Glucanase from the gram-negative bacterium Flavobacterium sp. EK-14 hydrolyzes fungal cell wall α-1,3-glucan
errSCIENTIFIC REPORTS
IF3.9
err2023-12-05
err2
errOAAI
errTakahashi, Masaki; Yano, Shigekazu; Horaguchi, Yui; Otsuka, Yuitsu; Suyotha, Wasana; Makabe, Koki; Konno, Hiroyuki; Kokeguchi, Susumu
err分享
err收藏
Development and Assessment of 1,5-Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK-2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation
errMOLECULES
IF4.6
err2023-09-08
err3
errOAAI
errAbdelrahman, Kamal S.; Hassan, Heba A.; Abdel-Aziz, Salah A.; Marzouk, Adel A.; Shams, Raef; Osawa, Keima; Abdel-Aziz, Mohamed; Konno, Hiroyuki
err分享
err收藏
Structure-Activity Relationship Study of N-Hydroxyphtalimide Derivatives for the Detection of Amines during Fmoc-Solid-Phase Peptide SynthesisN-羟基邻苯二甲酰亚胺衍生物在Fmoc-固相肽合成过程中用于胺检测的构效关系研究
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2023-01-19
err4
PREAI
errTakamatsu, Keigo; Suzuki, Rio; Matsunaga, Amane; Katagiri, Hiroshi; Konno, Hiroyuki
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err收藏
Synthesis and Configuration Confirmation of the ATHOD Fatty Amino Acid Residue in the Burkholdines
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2022-07-19
err2
PREAI
errKadowaki, Toma; Kainuma, Rin; Kato, Seiya; Konno, Hiroyuki
err分享
err收藏
The Hydrophobicity and Antifungal Potentiation of Burkholdine Analogues
errMOLECULES
IF4.6
err2022-02-10
err3
errOAAI
errKonno, Hiroyuki; Sasaki, Mio; Sano, Hinata; Osawa, Keima; Nosaka, Kazuto; Yano, Shigekazu
err分享
err收藏
Artificial intelligence-based classification of peripheral blood nucleated cells using label-free imaging flow cytometry
errLAB ON A CHIP
IF5.4
err2022-01-01
err6
PREAI
errHirotsu, Amane; Kikuchi, Hirotoshi; Yamada, Hidenao; Ozaki, Yusuke; Haneda, Ryoma; Kawata, Sanshiro; Murakami, Tomohiro; Matsumoto, Tomohiro; Hiramatsu, Yoshihiro; Kamiya, Kinji; Yamashita, Daisuke; Fujimori, Yuki; Ueda, Yukio; Okazaki, Shigetoshi; Kitagawa, Masatoshi; Konno, Hiroyuki; Takeuchi, Hiroya
err分享
err收藏
Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2021-12-01
err75
PREAI
errSoltan, Osama M.; Shoman, Mai E.; Abdel-Aziz, Salah A.; Narumi, Atsushi; Konno, Hiroyuki; Abdel-Aziz, Mohamed
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Motomu Kanai
H 指数: 97 · 论文数: 727
K
Keiichi I. Nakayama
H 指数: 95 · 论文数: 558
T
Takeshi Fujita
H 指数: 90 · 论文数: 709
M
Marcus Conrad
H 指数: 89 · 论文数: 259
Y
Yuko Kitagawa
H 指数: 88 · 论文数: 1.9K
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