Filomena Fezza - Publications, H-index & Citations

Filomena Fezza

University of Rome Tor Vergata

46H指数

102论文数

1.1W被引数

收录论文 54

发表时间

Fatty acid amide hydrolase (FAAH) inhibitor design and preclinical studies: lessons learned from BIA 10–2474 and the challenges ahead 脂肪酸酰胺水解酶（FAAH）抑制剂的设计与临床前研究：从BIA 10–2474中吸取的教训及面临的挑战

Expert Opinion on Drug Discovery

IF4.9

2026-08-19

OAAI

Alessia Catalano; Filomena Fezza; Andrea Duranti; Maria Maddalena Cavalluzzi; Giovanni Lentini; Giuseppe Felice Mangiatordi; Marco Bruno Luigi Rocchi; Mauro Maccarrone

Lipid Composition Drives Mutant Huntingtin Dimerization and Membrane Association: Insights from Computational Simulations 脂质组成驱动突变亨廷蛋白二聚化和膜结合：计算模拟的见解

Molecules

IF4.6

2026-06-05

OAAI

Catalin Nicoara; Emanuele Criscuolo; Angela De Cristofaro; Filomena Fezza; Mauro Maccarrone

FAAH Modulators from Natural Sources: A Collection of New Potential Drugs 天然来源的FAAH调节剂：新潜在药物的集合

CELLS

IF5.2

2025-04-05

OAAI

Nicoara, Catalin; Fezza, Filomena; Maccarrone, Mauro

Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1 FDA批准的针对大麻素受体CB1的化合物的计算和实验药物再利用

PHARMACEUTICALS

IF4.8

2023-12-02

OAAI

Criscuolo, Emanuele; De Sciscio, Maria Laura; De Cristofaro, Angela; Nicoara, Catalin; Maccarrone, Mauro; Fezza, Filomena

Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437

ACS CHEMICAL BIOLOGY

IF3.8

2022-04-28

OAAI

Gagestein, Berend; Stevens, Anna F.; Fazio, Domenico; Florea, Bogdan, I; van der Wel, Tom; Bakker, Alexander T.; Fezza, Filomena; den Dulk, Hans; Overkleeft, Herman S.; Maccarrone, Mauro; van der Stelt, Mario

Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents

ACS CHEMICAL NEUROSCIENCE

IF3.9

2021-04-23

OAAI

Grillo, Alessandro; Fezza, Filomena; Chemi, Giulia; Colangeli, Roberto; Brogi, Simone; Fazio, Domenico; Federico, Stefano; Papa, Alessandro; Relitti, Nicola; Di Maio, Roberto; Giorgi, Gianluca; Lamponi, Stefania; Valoti, Massimo; Gorelli, Beatrice; Saponara, Simona; Benedusi, Mascia; Pecorelli, Alessandra; Minetti, Patrizia; Valacchi, Giuseppe; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra; Maccarrone, Mauro; Di Giovanni, Giuseppe

In Silico and In Vitro Analysis of Major Cannabis-Derived Compounds as Fatty Acid Amide Hydrolase Inhibitors

MOLECULES

IF4.6

2020-12-24

OAAI

Criscuolo, Emanuele; De Sciscio, Maria Laura; Fezza, Filomena; Maccarrone, Mauro

Characterization of Endocannabinoid System and Interleukin Profiles in Ovine AEC: Cannabinoid Receptors Type-1 and Type-2 as Key Effectors of Pro-Inflammatory Response

CELLS

IF5.2

2020-04-18

OAAI

Greco, Luana; Russo, Valentina; Rapino, Cinzia; Di Germanio, Clara; Fezza, Filomena; Bernabo, Nicola; Berardinelli, Paolo; Peserico, Alessia; Fazio, Domenico; Maccarrone, Mauro; Mattioli, Mauro; Barboni, Barbara

Advances in the discovery of fatty acid amide hydrolase inhibitors: what does the future hold?

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2020-04-15

PREAI

Fazio, Domenico; Criscuolo, Emanuele; Piccoli, Alessandra; Barboni, Barbara; Fezza, Filomena; Maccarrone, Mauro

The endocannabinoid hydrolase FAAH is an allosteric enzyme (vol 10, 2292, 2020)

SCIENTIFIC REPORTS

IF3.9

2020-03-31

OAAI

Dainese, Enrico; Oddi, Sergio; Simonetti, Monica; Sabatucci, Annalaura; Angelucci, Clotilde B.; Ballone, Alice; Dufrusine, Beatrice; Fezza, Filomena; De Fabritiis, Gianni; Maccarrone, Mauro

The endocannabinoid hydrolase FAAH is an allosteric enzyme

SCIENTIFIC REPORTS

IF3.9

2020-02-10

OAAI

Dainese, Enrico; Oddi, Sergio; Simonetti, Monica; Sabatucci, Annalaura; Angelucci, Clotilde B.; Ballone, Alice; Dufrusine, Beatrice; Fezza, Filomena; De Fabritiis, Gianni; Maccarrone, Mauro

Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-12-01

OAAI

Grillo, Alessandro; Chemi, Giulia; Brogi, Simone; Brindisi, Margherita; Relitti, Nicola; Fezza, Filomena; Fazio, Domenico; Castelletti, Laura; Perdona, Elisabetta; Wong, Andrea; Lamponi, Stefania; Pecorelli, Alessandra; Benedusi, Mascia; Fantacci, Manuela; Valoti, Massimo; Valacchi, Giuseppe; Micheli, Fabrizio; Novellino, Ettore; Campiani, Giuseppe; Butini, Stefania; Maccarrone, Mauro; Gemma, Sandra

Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2017-05-01

PREAI

Oddi, Sergio; Stepniewski, Tomasz Maciej; Totaro, Antonio; Selent, Jana; Scipioni, Lucia; Dufrusine, Beatrice; Fezza, Filomena; Dainese, Enrico; Maccarrone, Mauro

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

NATURE COMMUNICATIONS

IF15.7

2017-01-03

282

OAAI

Soethoudt, Marjolein; Grether, Uwe; Fingerle, Juergen; Grim, Travis W.; Fezza, Filomena; de Petrocellis, Luciano; Ullmer, Christoph; Rothenhausler, Benno; Perret, Camille; van Gils, Noortje; Finlay, David; MacDonald, Christa; Chicca, Andrea; Gens, Marianela Dalghi; Stuart, Jordyn; de Vries, Henk; Mastrangelo, Nicolina; Xia, Lizi; Alachouzos, Georgios; Baggelaar, Marc P.; Martella, Andrea; Mock, Elliot D.; Deng, Hui; Heitman, Laura H.; Connor, Mark; Di Marzo, Vincenzo; Gertsch, Jurg; Lichtman, Aron H.; Maccarrone, Mauro; Pacher, Pal; Glass, Michelle; van der Stelt, Mario

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS

SCIENTIFIC REPORTS

IF3.9

2016-06-17

OAAI

Bilgin, Mesut; Born, Petra; Fezza, Filomena; Heimes, Michael; Mastrangelo, Nicolina; Wagner, Nicolai; Schultz, Carsten; Maccarrone, Mauro; Eaton, Suzanne; Nadler, Andre; Wilm, Matthias; Shevchenko, Andrej

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2016-01-15

OAAI

Mukhopadhyay, Partha; Baggelaar, Marc; Erdelyi, Katalin; Cao, Zongxian; Cinar, Resat; Fezza, Filomena; Ignatowska-Janlowska, Bogna; Wilkerson, Jenny; van Gils, Noortje; Hansen, Thomas; Ruben, Marc; Soethoudt, Marjolein; Heitman, Laura; Kunos, George; Maccarrone, Mauro; Lichtman, Aron; Pacher, Pal; Van der Stelt, Mario

Endocannabinoids, Related Compounds and Their Metabolic Routes

MOLECULES

IF4.6

2014-10-24

148

OAAI

Fezza, Filomena; Bari, Monica; Florio, Rita; Talamonti, Emanuela; Feole, Monica; Maccarrone, Mauro

Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor

ATHEROSCLEROSIS

IF5.7

2014-03-01

PREAI

Chiurchiu, Valerio; Lanuti, Mirko; Catanzaro, Giuseppina; Fezza, Filomena; Rapino, Cinzia; Maccarrone, Mauro

Activation of type-2 cannabinoid receptor inhibits neuroprotective and antiinflammatory actions of glucocorticoid receptor α: when one is better than two

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2013-01-08

OAAI

Bisicchia, Elisa; Chiurchiu, Valerio; Viscomi, Maria Teresa; Latini, Laura; Fezza, Filomena; Battistini, Luca; Maccarrone, Mauro; Molinari, Marco

Rat and human fatty acid amide hydrolases: Overt similarities and hidden differences

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2012-11-01

PREAI

Di Venere, Almerinda; Dainese, Enrico; Fezza, Filomena; Angelucci, Beatrice Clotilde; Rosato, Nicola; Cravatt, Benjamin F.; Finazzi-Agro, Alessandro; Mei, Giampiero; Maccarrone, Mauro

研究方向