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收藏分享 收藏 Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid口服生物利用且位点选择性的基于大环海洋二萜类化合物的共价STING抑制剂
Niu, Guang-Hao; Hsiao, Wan-Chi; Lee, Po-Hsun; Zheng, Li-Guo; Yang, Yu-Shao; Huang, Wei-Cheng; Hsieh, Chih-Chien; Chiu, Tai-Yu; Wang, Jing-Ya; Chen, Ching-Ping; Huang, Chen-Lung; You, May-Su; Kuo, Yi-Ping; Wang, Chien-Ming; Wen, Zhi-Hong; Yu, Guann-Yi; Chen, Chiung-Tong; Chi, Ya-Hui; Tung, Chun-Wei; Hsu, Shu-Ching; Yeh, Teng-Kuang; Sung, Ping-Jyun; Zhang, Mingzi M.; Tsou, Lun Kelvin 分享 收藏 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin (vol 215,115688,2023)Yang, Cheng-Wei; Hsu, Hsing-Yu; Lee, Yue-Zhi; Jan, Jia-Tsrong; Chang, Sui-Yuan; Lin, Yi-Ling; Yang, Ruey-Bing; Chao, Tai-Ling; Liang, Jian-Jong; Lin, Shu-Jing; Liao, Chun-Che; Chang, Chih-Shin; Sytwu, Huey-Kang; Hung, Ming-Shiu; Chen, Chiung-Tong; Lee, Shiow-Ju 分享 收藏 分享 收藏 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesiaHuang, Yi-Han; Lin, Shu-Yu; Ou, Li-Chin; Huang, Wei-Cheng; Chao, Po-Kuan; Chang, Yung-Chiao; Chang, Hsiao-Fu; Lee, Pin-Tse; Yeh, Teng-Kuang; Kuo, Yu-Hsien; Tien, Ya-Wen; Xi, Jing-Hua; Tao, Pao-Luh; Chen, Pin-Yuan; Chuang, Jian-Ying; Shih, Chuan; Chen, Chiung-Tong; Tung, Chun-Wei; Loh, Horace H.; Ueng, Shau-Hua; Yeh, Shiu-Hwa 分享 收藏 Discovery of a Long Half-Life AURKA Inhibitor to Treat MYC-Amplified Solid Tumors as a Monotherapy and in Combination with EverolimusChang, Chun-Ping; Yeh, Teng-Kuang; Chen, Chiung-Tong; Wang, Wan-Ping; Chen, Yen-Ting; Tsai, Chia-Hua; Chen, Yan-Fu; Ke, Yi-Yu; Wang, Jing-Ya; Chen, Ching-Ping; Hsieh, Tsung-Chih; Wu, Mine-Hsine; Huang, Chen-Lung; Chen, Ya-Ping; Zhuang, Hong; Chi, Ya-Hui 分享 收藏 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimusChi, Ya-Hui; Chang, Chun-Ping; Yeh, Teng-Kuang; Chen, Chiung-Tong; Wang, Wan-Ping; Chen, Yen-Ting; Tsai, Chia-Hua; Chen, Yan-Fu; Ke, Yi-Yu; Wang, Jing-Ya; Chen, Ching-Ping; Hsieh, Tsung-Chih; Wu, Mine-Hsine; Huang, Chen-Lung; Chen, Ya-Ping; Zhuang, Hong 分享 收藏 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin天然岩藻多糖通过靶向病毒刺突蛋白和宿主细胞弗林蛋白酶抑制冠状病毒Yang, Cheng-Wei; Hsu, Hsing-Yu; Lee, Yue-Zhi; Jan, Jia-Tsrong; Chang, Sui-Yuan; Lin, Yi-Ling; Yang, Ruey-Bing; Chao, Tai-Ling; Liang, Jian-Jong; Lin, Shu-Jing; Liao, Chun-Che; Chang, Chih-Shin; Sytwu, Huey-Kang; Hung, Ming-Shiu; Chen, Chiung-Tong; Lee, Shiow-Ju 分享 收藏 Targeting mycamplified cancers with a novel prodrug inhibiting aurora A kinaseChi, Ya-Hui; Chang, Chun-Ping; Yeh, Teng-Kuang; Wang, Wan-Ping; Chen, Yen-Ting; Tsai, Chia-Hua; Chen, Yan-Fu; Ke, Yi-Yu; Wang, Jing-Ya; Chen, Ching-Ping; Hsieh, Tsung-Chih; Wu, Mine-Hsine; Chen, Chiung-Tong 分享 收藏 Development of Furanopyrimidine-Based Orally Active Third- Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung CancerLi, Mu -Chun; Coumar, Mohane Selvaraj; Lin, Shu-Yu; Lin, Yih-Shyan; Huang, Guan-Lin; Chen, Chun-Hwa; Lien, Tzu-Wen; Wu, Yi-Wen; Chen, Yen-Ting; Chen, Ching-Ping; Huang, Yu-Chen; Yeh, Kai-Chia; Yang, Chen -Ming; Kalita, Bikashita; Pan, Shiow-Lin; Hsu, Tsu-An; Yeh, Teng-Kuang; Chen, Chiung-Tong; Hsieh, Hsing-Pang 分享 收藏 Lee et al. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics (vol 14, 1511, 2022)Lee, Yue-Zhi; Hsu, Hsing-Yu; Yang, Cheng-Wei; Lin, Yi-Ling; Chang, Sui-Yuan; Yang, Ruey-Bing; Liang, Jian-Jong; Chao, Tai-Ling; Liao, Chun-Che; Kao, Han-Chieh; Chang, Jang-Yang; Sytwu, Huey-Kang; Chen, Chiung-Tong; Lee, Shiow-Ju 分享 收藏 Omicron-specific mRNA vaccine induced cross-protective immunity against ancestral SARS-CoV-2 infection with low neutralizing antibodiesOmicron特异性mRNA疫苗诱导低中和抗体对祖先SARS-CoV-2感染的交叉保护性免疫Shen, Kuan-Yin; Yang, Chung-Hsiang; Chen, Chiung-Tong; Ho, Hui-Min; Chiu, Fang-Feng; Huang, Chiung-Yi; Liao, Hung-Chun; Hsu, Chia-Wei; Yu, Guann-Yi; Liao, Ching-Len; Chen, Hsin-Wei; Huang, Ming-Hsi; Liu, Shih-Jen 分享 收藏 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipationKuppusamy, Ramajayam; Hsu, Ying-Ting; Ke, Yi-Yu; Chang, Po-Wei; Chang, Yung-Chiao; Chang, Hsiao-Fu; Wang, Pei-Chen; Lin, Yu-Hao; Huang, Yu-Chen; Yeh, Teng-Kuang; Chuang, Jian-Ying; Loh, Horace H.; Shih, Chuan; Chen, Chiung-Tong; Yeh, Shiu-Hwa; Ueng, Shau-Hua 分享 收藏 Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis用于检测包裹性腹膜硬化的腹膜流出物MicroRNA谱Wu, Kun-Lin; Chou, Che-Yi; Chang, Hui-Yin; Wu, Chih-Hsun; Li, An-Lun; Chen, Chien-Lung; Tsai, Jen-Chieh; Chen, Yi-Fan; Chen, Chiung-Tong; Tseng, Chin-Chung; Chen, Jin-Bor; Wang, I-Kuan; Hsu, Yu-Juei; Lin, Shih-Hua; Huang, Chiu-Ching; Ma, Nianhan 分享 收藏 Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid ConjugateLo, Chen-Fu; Chiu, Tai-Yu; Liu, Yu-Tzu; Pan, Pei-Yun; Liu, Kuan-Liang; Hsu, Chia-Yu; Fang, Ming-Yu; Huang, Yu-Chen; Yeh, Teng-Kuang; Hsu, Tsu-An; Chen, Chiung-Tong; Huang, Li-Rung; Tsou, Lun Kelvin 分享 收藏 The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33bLee, Yue-Zhi; Hsu, Hsing-Yu; Yang, Cheng-Wei; Lin, Yi-Ling; Chang, Sui-Yuan; Yang, Ruey-Bing; Liang, Jian-Jong; Chao, Tai-Ling; Liao, Chun-Che; Kao, Han-Chieh; Chang, Jang-Yang; Sytwu, Huey-Kang; Chen, Chiung-Tong; Lee, Shiow-Ju 分享 收藏 Synthesis and Evaluation of Small Molecule Drug Conjugates Harnessing Thioester-Linked Maytansinoids利用硫酯连接的美登素类小分子药物缀合物的合成与评价Lo, Chen-Fu; Chiu, Tai-Yu; Liu, Yu-Tzu; Huang, Li-Rung; Yeh, Teng-Kuang; Huang, Kuan-Hsun; Liu, Kuan-Liang; Hsu, Chia-Yu; Fang, Ming-Yu; Huang, Yu-Chen; Hsu, Tsu-An; Chen, Chiung-Tong; Tsou, Lun Kelvin 分享 收藏 A Noninvasive Gut-to-Brain Oral Drug Delivery System for Treating Brain Tumors (vol 33, 2100701, 2021)Miao, Yang-Bao; Chen, Kuan-Hung; Chen, Chiung-Tong; Mi, Fwu-Long; Lin, Yu-Jung; Chang, Yen; Chiang, Chi-Shiun; Wang, Jui-To; Lin, Kun-Ju; Sung, Hsing-Wen 分享 收藏 Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection弗林蛋白酶和TMPRSS2抗性尖峰诱导强大的体液和细胞免疫，以抵抗SARS-CoV-2致死性感染Lin, Jhe-Jhih; Tien, Chih-Feng; Kuo, Yi-Ping; Lin, En-Ju; Tsai, Wei-Hsiang; Chen, Ming-Yu; Tsai, Pei-Ju; Su, Yu-Wen; Pathak, Nikhil; Yang, Jinn-Moon; Yu, Chia-Yi; Chuang, Zih-Shiuan; Wu, Han-Chieh; Tsai, Wan-Ting; Dai, Shih-Syong; Liao, Hung-Chun; Chai, Kit Man; Su, Yu-Siang; Chuang, Tsung-Hsien; Liu, Shih-Jen; Chen, Hsin-Wei; Dou, Horng-Yunn; Chen, Feng-Jui; Chen, Chiung-Tong; Liao, Chin-Len; Yu, Guann-Yi 分享 收藏 
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