Oscar P. J. van Linden

Faculty of Science

5H指数

11论文数

523被引数

收录论文 7

发表时间

Combined cellular and biochemical profiling of Bruton’s tyrosine kinase inhibitor nemtabrutinib reveals potential application in MAPK-driven cancers 联合细胞和生物化学分析表明，Bruton’s tyrosine kinase抑制剂nemtabrutinib在MAPK驱动的癌症中具有潜在应用价值。

Frontiers in Oncology

IF3.3

2025-10-22

OAAI

Daphne J. F. Kluitmans; Janneke J. T. M. Melis; Esmee van den Bossche; Jacob Ytsma; Jeroen A. D. M. de Roos; Oscar P. J. van Linden; Yvonne Grobben; Jeffrey J. Kooijman; Guido J. R. Zaman†

Design and synthesis of photoswitchable desloratadine ligands for histamine H1 receptor photopharmacology 光控去氯雷他定配体的设计与合成及其在组胺H1受体光药理学中的应用

RSC Med. Chem.

IF3.6

2025-08-14

OAAI

Lars Binkhorst; Ivana Josimovic; Daan de Vetten; Tyrone Nijman; Niels Hauwert; Sufyan Ahmad; Oscar P.J. van Linden; Iwan de Esch; Henry Vischer; Maikel Wijtmans; Rob Leurs

From recipe to research: introducing undergraduate students to the nature o science using a hybrid practical course centred on drug discovery for neglected diseases

DRUG DISCOVERY TODAY

IF7.5

2021-06-01

OAAI

Wijtmans, Maikel; Edink, Ewald; van Linden, Oscar P. J.; Zheng, Yang; Blaazer, Antoni R.; Siderius, Marco; van Muijlwijk-Koezen, Jacqueline E.

KLIFS: a structural kinase-ligand interaction database

NUCLEIC ACIDS RESEARCH

IF13.1

2015-10-22

167

OAAI

Kooistra, Albert J.; Kanev, Georgi K.; van Linden, Oscar P. J.; Leurs, Rob; de Esch, Iwan J. P.; de Graaf, Chris

KLIFS: A Knowledge-Based Structural Database To Navigate Kinase-Ligand Interaction Space

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-09-20

252

PREAI

van Linden, Oscar P. J.; Kooistra, Albert J.; Leurs, Rob; de Esch, Lwan J. P.; de Graaf, Chris

Regiochemistry of the Condensation of 2-Aroyl-cyclohexanones and 2-Cyanoacetamide: 13C-Labeling Studies and Semiempirical MO Calculations

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2012-08-16

PREAI

van Linden, Oscar P. J.; Wijtmans, Maikel; Roumen, Luc; Rotteveel, Lonneke; Leurs, Rob; de Esch, Iwan. J. P.

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2012-01-01

PREAI

van Linden, Oscar P. J.; Farenc, Carine; Zoutman, Willem H.; Hameetman, Liesbeth; Wijtmans, Maikel; Leurs, Rob; Tensen, Cornelis P.; Siegal, Gregg; de Esch, Iwan J. P.

研究方向