未登录Translational and clinical development of therapeutic siRNA and ASOs: current industry practices, perspectives, and recommendations治疗性siRNA和ASOs的转化与临床开发：当前行业实践、观点和建议
Christensen, Jesper Kammersgaard; Colletti, Nicholas; Hooshfar, Shirin; Jiang, Rongrong(Rosa); Kuo, Carol; Lindmark, Bosse; Lumen, Annie; Youssef, Amir S.; Albertolle, Matthew; Aluri, Krishna C.; Chen, Linzhi; Chen, Jingxian; Chopda, Girish; Chua, Xien Yu; Morais, Pedro; Dubois, Barent; Gibbons, Francis (Frank); Gudey, Shyam Kumar; Gupta, Swati; Hood, Steve; Humphreys, Sara; Husser, Christophe; Huth, Felix; Jani, Darshana; Jian, Wenying; Kakuda, Thomas; Kurz, Jeffrey; Linnebjerg, Helle; Liu, Jing; Lohmann, Sabine; Niu, Tao; Root, Katharina; Singla, Sumeet; Tang, Chenxiao; Veluri, Ravikanth; Zhang, Guangnong (Sunny); Zhang, Steven; Jawa, Vibha .png)
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收藏Design, synthesis and preclinical evaluation of bio-conjugated amylinomimetic peptides as long-acting amylin receptor agonists长效胰淀素受体激动剂生物偶联拟淀粉肽的设计、合成及临床前评价Patch, Raymond J.; Zhang, Rui; Edavettal, Suzanne; Macielag, Mark J.; Eckardt, Annette J.; Li, Jiali; Rives, Marie-Laure; Edwards, Wilson; Hinke, Simon A.; Qiu, Xi; Jian, Wenying; Libiger, Ondrej; Zheng, Songmao; Jeyaseelan, Jey; Liang, Yin; Rangwala, Shamina M.; Leonard, James N.; Hornby, Pamela 分享 收藏 分享 收藏 Amino acids are sensitive glucagon receptor-specific biomarkers for glucagon-like peptide-1 receptor/glucagon receptor dual agonists氨基酸是胰高血糖素样肽-1受体/胰高血糖素受体双重激动剂的敏感的胰高血糖素受体特异性生物标志物Li, Wenyu; Kirchner, Thomas; Ho, George; Bonilla, Fany; D'Aquino, Katharine; Littrell, James; Zhang, Rui; Jian, Wenying; Qiu, Xi; Zheng, Songmao; Gao, Bin; Wong, Peggy; Leonard, James N.; Camacho, Raul C. 分享 收藏 Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry PerspectiveKellie, John F.; Tran, John C.; Jian, Wenying; Jones, Barry; Mehl, John T.; Ge, Ying; Henion, Jack; Bateman, Kevin P. 分享 收藏 Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activityCamacho, Raul C.; You, Seohee; D'Aquino, Katharine E.; Li, Wenyu; Wang, Yuanping; Gunnet, Joseph; Littrell, James; Qi, Jian Shen; Kang, Lijuan; Jian, Wenying; MacDonald, Mary; Tat, Timothy; Steiner, Derek; Zhang, Yue-Mei; Lanter, James; Patch, Raymond; Zhang, Rui; Li, Jiali; Edavettal, Suzanne; Edwards, Wilson; Dinh, Thai; Wang, Li Ying; Connor, Judy; Hunter, Michael; Chi, Ellen; Swanson, Ronald V.; Leonard, James N.; Case, Martin A. 分享 收藏 A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman PrimatesRangwala, Shamina M.; D'Aquino, Katharine; Zhang, Yue-Mei; Bader, Lindsay; Edwards, Wilson; Zheng, Songmao; Eckardt, Annette; Lacombe, Ann; Pick, Rebecca; Moreno, Veronica; Kang, Lijuan; Jian, Wenying; Arnoult, Eric; Case, Martin; Jenkinson, Celia; Chi, Ellen; Swanson, Ronald, V; Kievit, Paul; Grove, Kevin; Macielag, Mark; Erion, Mark D.; SinhaRoy, Ranabir; Leonard, James N. 分享 收藏 Cholesterol 7 Alpha-Hydroxylase (CYP7A1) Activity and 7-Alpha-Hydroxy-4-Cholesten-3-One (C4) Are Not Translatable Biomarkers of Glucagon Receptor (GCGR) ActivationCamacho, Raul; Li, Wenyu; Kirchner, Thomas; Zhang, Rui; Bonilla, Fany; Jian, Wenying; Gao, Bin; Sinharoy, Ranabir; Leonard, James; Connolly, Thomas 分享 收藏 LC/MS/MS Bioanalysis of Protein-Drug Conjugates-The Importance of Incorporating Succinimide Hydrolysis ProductsShi, Chuan; Goldberg, Shalom; Lin, Tricia; Dudkin, Vadim; Widdison, Wayne; Harris, Luke; Wilhelm, Sharon; Jmeian, Yazen; Davis, Darryl; O'Neil, Karyn; Weng, Naidong; Jian, Wenying 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Tissue distribution and tumor uptake of novel folate receptor targeted epothilone, BMS-745493 in CD2F1 mice after systemic administrationGan, Jinping; Wang, Lifei; Shen, Hong; Jian, Wenying; Menard, Krista; Hong, Yang; Yuan, Tian; Zhang, Duxi; Bonacorsi, Samuel; Lee, Francis 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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