未登录

C

Chafen Lu

Harvard University

H指数:40

被引数:5,312

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20190

OAAI

Monomeric prefusion structure of an extremophile gamete fusogen and stepwise formation of the postfusion trimeric state

NATURE COMMUNICATIONS

IF15.7

2022-07-133

OAAI

Von Willebrand factor A1 domain stability and affinity for GPIbα are differentially regulated by its O-glycosylated N- and C-linker

血管性血友病因子A1结构域的稳定性和对gpib α 的亲和力受其O-糖基化N-和C-接头的差异调节

IF0

2022-05-093

OA

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

IF0

2021-12-2310

OA

Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP

IF0

2020-07-1013

OAAI

Fusion surface structure, function, and dynamics of gamete fusogen HAP2

IF0

2018-10-0327

OA

Prodomain-growth factor swapping in the structure of pro-TGF-1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-02-0133

OAAI

High integrin αVβ6 affinity reached by hybrid domain deletion slows ligand-binding on-rate

通过杂合结构域缺失达到的高整合素 αVβ6亲和力减慢了配体结合速率

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-01-2918

OAAI

Atypical interactions of integrin αVβ8 with pro-TGF-β1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-05-0838

OAAI

Conformational equilibria and intrinsic affinities define integrin activation

构象平衡和内在亲和力定义了整合素的激活

IF8.3

2017-01-25119

OAAI

Relating conformation to function in integrin α5β1

整合素 α5β1中构象与功能的关系

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-06-17124

OAAI

Structural determinants of integrin β-subunit specificity for latent TGF-β

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2014-11-10124

OAAI

Shape change in the receptor for gliding motility in Plasmodium sporozoites

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-12-1163

OAAI

Mechanisms for Kinase-mediated Dimerization of the Epidermal Growth Factor Receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-11-0166

OAAI

Unexpected fold in the circumsporozoite protein target of malaria vaccines

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-04-3095

OAAI

GARP regulates the bioavailability and activation of TGFβ

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2012-03-15179

OAAI

A pH-regulated dimeric bouquet in the structure of von Willebrand factor

von Willebrand因子结构中的pH调节二聚体花束

IF8.3

2011-08-19102

OA

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2011-08-07110

OA

Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-06-09183

OAAI

Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2

CELLULAR SIGNALLING

IF3.7

2006-12-0165

PREAI