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J

Julia Mantaj

franklin-wilkins building
H指数:12
被引数:653
浏览量:0

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Synthesis, SAR and Biophysical Mechanism of Action of Cyclopropabenzindole-Pyridinobenzodiazepine (CBI-PDD) Guanine-Adenine DNA Cross-Linking Agents

环丙烷苯并吲哚-吡啶苯并二氮杂-CBI-PDD鸟嘌呤-腺嘌呤DNA交联剂的合成、构效关系及生物物理作用机制

European Journal of Medicinal Chemistry
IF5.9
2025-09-260
PRE
George Procopiou; Paul J.M. Jackson; Daniella di Mascio; Jennifer L. Auer; Paolo Andriollo; Ilona Pysz-Hosey; Julia Mantaj; Khondaker Miraz Rahman; Keith R. Fox; David E. Thurston
Cow Milk and Intestinal Epithelial Cell-Derived Extracellular Vesicles as Systems for Enhancing Oral Drug Delivery
PHARMACEUTICS
IF5.5
2020-03-04101
OAAI
Carobolante, Greta; Mantaj, Julia; Ferrari, Enrico; Vllasaliu, Driton
Delivery of Nanoparticles across the Intestinal Epithelium via the Transferrin Transport Pathway
PHARMACEUTICS
IF5.5
2019-06-2637
OAAI
Yong, Jing M.; Mantaj, Julia; Cheng, Yiyi; Vllasaliu, Driton
Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics
PHARMACEUTICS
IF5.5
2019-03-1936
OAAI
Aprodu, Andreea; Mantaj, Julia; Raimi-Abraham, Bahijja; Vllasaliu, Driton
Ascorbyl Palmitate Hydrogel for Local, Intestinal Delivery of Macromolecules
PHARMACEUTICS
IF5.5
2018-10-1516
OAAI
Zhai, Jinyi; Mantaj, Julia; Vllasaliu, Driton
Pyridinobenzodiazepines (PDDs): A new class of sequence-selective DNA mono-alkylating ADC payloads with low hydrophobicity
CANCER RESEARCH
IF16.6
2018-07-013
PRE
Veillard, Nicolas; Andriollo, Paolo; Mantaj, Julia; Fox, Keith R.; Rahman, K. Miraz; Procopiou, George; Cascio, Francesco; Corcoran, David B.; Pysz, Ilona; Cooper, Patricia A.; Shnyder, Steven D.; Ju, Yawen; Tan, Edwin; Schopperle, William M.; Jackson, Paul J.; Thurston, David E.
Further evidence that the DNA-interactive Pyrrolobenzodiazepine (PBD) Dimer SJG-136 works through a transcription factor inhibition mechanism
CANCER RESEARCH
IF16.6
2017-07-010
PRE
Mantaj, Julia; Jackson, Paul J.; Thurston, David E.; Rahman, Khondaker Miraz
From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs)
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2016-11-15220
OAAI
Mantaj, Julia; Jackson, Paul J. M.; Rahman, Khondaker M.; Thurston, David E.
Covalent bonding of a C8-conjugated pyrrolobenzodiazepine (PBD) monomer and dimer to a terminal guanine residue of DNA duplex and hairpin fragments
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Mantaj, Julia; Jackson, Paul J. M.; Jackson, Khondaker Miraz; Thurston, David E.
In silico design, synthesis and evaluation of a new family of Cl-substituted pyrrolobenzodiazepines (PBDs)
CANCER RESEARCH
IF16.6
2016-07-151
PRE
Jackson, Paul J. M.; Procopiou, George; Veillard, Nicolas; Mantaj, Julia; Rahman, K. Miraz; Thurston, David E.
Effect of the PBD dimer SJG-136 on expression of STAT3 dependent genes
CANCER RESEARCH
IF16.6
2015-08-012
PRE
Mantaj, Julia; Thurston, David E.; Rahman, Khondaker M.
Interaction of SJG-136 with cognate sequences of oncogenic transcription factors
EUROPEAN JOURNAL OF CANCER
IF7.1
2014-11-010
PREAI
Mantaj, J.; Jackson, P. J.; Thurston, D. E.; Rahman, K. M.
C8-linked pyrrolobenzodiazepine (pbd)-benzofused conjugates with low-picomolar in vitro cytotoxicity
CANCER RESEARCH
IF16.6
2014-10-010
PRE
Mantaj, Julia; Jackson, Paul J. M.; Pepper, Chris; Thurston, David E.; Rahman, Khondaker M.

研究方向

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D
David E. Thurston
H 指数:45论文数:341被引数:7,111
K
Khondaker Miraz Rahman
H 指数:33论文数:272被引数:4,525
P
Paul J. Jackson
H 指数:32论文数:170被引数:3,917
D
Driton Vllasaliu
H 指数:30论文数:79被引数:3,240
G
George Procopiou
H 指数:4论文数:23被引数:82
P
Paolo Andriollo
H 指数:4论文数:66被引数:92
K
Keith R. Fox
H 指数:44论文数:252被引数:6,955
N
Nicolas Veillard
H 指数:4论文数:19被引数:110
C
Chris Pepper
H 指数:50论文数:305被引数:6,966
E
Edwin C.K. Tan
H 指数:29论文数:155被引数:4,293