未登录 Global Health Priority Box-Proactive Pandemic Preparedness Adam, Anna; Besson, Dominique; Bryant, Rob; Rees, Sarah; Willis, Paul A.; Burrows, Jeremy N.; van Huisjduijnen, Rob Hooft; Laleu, Benoit; Norton, Larry; Canan, Stacie; Hawryluk, Natalie; Robinson, Dale; Palmer, Mike; Samby, Kirandeep Kaur 分享 收藏
The Pandemic Response Box Accelerating Drug Discovery Efforts after Disease Outbreaks Samby, Kirandeep; Besson, Dominique; Dutta, Anirban; Patra, Buddhadev; Doy, Angelique; Glossop, Paul; Mills, James; Whitlock, Gavin; van Huijsduijnen, Rob Hooft; Monaco, Alessandra; Bilbe, Graeme; Mowbray, Charles; Perry, Benjamin; Adam, Anna; Wells, Timothy N. C.; Willis, Paul A. 分享 收藏
An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials Tse, Edwin G.; Aithani, Laksh; Anderson, Mark; Cardoso-Silva, Jonathan; Cincilla, Giovanni; Conduit, Gareth J.; Galushka, Mykola; Guan, Davy; Hallyburton, Irene; Irwin, Benedict W. J.; Kirk, Kiaran; Lehane, Adele M.; Lindblom, Julia C. R.; Lui, Raymond; Matthews, Slade; McCulloch, James; Motion, Alice; Ng, Ho Leung; Oeren, Mario; Robertson, Murray N.; Spadavecchio, Vito; Tatsis, Vasileios A.; van Hoorn, Willem P.; Wade, Alexander D.; Whitehead, Thomas M.; Willis, Paul; Todd, Matthew H. 分享 收藏
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Substituted Aminoacetamides as Novel Leads for Malaria Treatment Norcross, Neil R.; Wilson, Caroline; Baragana, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cozar, Cristina; Sanz, Laura M.; Javier Gamo, Francisco; Avery, Vicky M.; Frearson, Julie A.; Gray, David W.; Fairlamb, Alan H.; Winzeler, Elizabeth A.; Waterson, David; Campbell, Simon F.; Willis, Paul A.; Read, Kevin D.; Gilbert, Ian H. 分享 收藏
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies Neelarapu, Raghupathi; Maignan, Jordany R.; Lichorowic, Cynthia L.; Monastyrskyi, Andrii; Mutka, Tina S.; LaCrue, Alexis N.; Blake, Lynn D.; Casandra, Debora; Mashkouri, Sherwin; Burrows, Jeremy N.; Willis, Paul A.; Kyle, Dennis E.; Manetsch, Roman 分享 收藏
Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol Abla, Nada; Bashyam, Sridevi; Charman, Susan A.; Greco, Beatrice; Hewitt, Philip; Belen Jimenez-Diaz, Maria; Katneni, Kasiram; Kubas, Holger; Picard, Didier; Sambandan, Yuvaraj; Sanz, Laura; Smith, Dennis; Wang, Tai; Willis, Paul; Wittlin, Sergio; Spangenberg, Thomas 分享 收藏
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold (vol 60, pg 6880, 2017) Sandoval, Elena; Lafuente-Monasterio, Maria Jose; Almela, Maria J.; Castaneda, Pablo; Diaz, Maria Belen Jimenez; Martinez-Martinez, Maria S.; Vidal, Jaume; Angulo-Barturen, Inigo; Bamborough, Paul; Burrows, Jeremy; Cammack, Nicholas; Chaparro, Maria J.; Coteron, Jose M.; de Cozar, Cristina; Crespo, Benigno; Diaz, Beatriz; Drewes, Gerard; Fernandez, Esther; Ferrer-Bazaga, Santiago; Fraile, Maria Teresa; Gamo, Francisco J.; Ghidelli-Disse, Sonja; Gomez, Ruben; Haselden, John; Huss, Sophie; Leon, Maria Luisa; de Mercado, Jaime; Macdonald, Simon J. F.; Hernando, Jose Ignacio Martin; Prats, Sara; Puente, Margarita; Rodriguez, Anne; de la Rosa, Juan C.; Rueda, Lourdes; Selenski, Carolyn; Willis, Paul; Wilson, David M.; Witty, Michael; Calderon, Felix 分享 收藏
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold Sandoval, Elena; Jose Lafuente-Monasterio, Maria; Almela, Maria J.; Castaneda, Pablo; Jimenez Diaz, Maria Belen; Martinez-Martinez, Maria S.; Vidal, Jaume; Angulo-Barturen, Inigo; Bamborough, Paul; Burrows, Jeremy; Cammack, Nicholas; Chaparro, Maria J.; Coteron, Jose M.; de Cozar, Cristina; Crespo, Benigno; Diaz, Beatriz; Drewes, Gerard; Fernandez, Esther; Ferrer-Bazaga, Santiago; Teresa Fraile, Maria; Gamo, Francisco J.; Ghidelli-Disse, Sonja; Gomez, Ruben; Haselden, John; Huss, Sophie; Luisa Leon, Maria; de Mercado, Jaime; Macdonald, Simon J. F.; Martin Hernando, Jose Ignacio; Prats, Sara; Puente, Margarita; Rodriguez, Anne; de la Rosa, Juan C.; Rueda, Lourdes; Selenski, Carolyn; Willis, Paul; Wilson, David M.; Witty, Michael; Calderon, Felix 分享 收藏
Susceptibility Testing of Medically Important Parasites Bayih, Abebe Genetu; Debnath, Anjan; Mitre, Edward; Huston, Christopher D.; Laleu, Benoit; Leroy, Didier; Blasco, Benjamin; Campo, Brice; Wells, Timothy N. C.; Willis, Paul A.; Sjo, Peter; Van Voorhis, Wesley C.; Pillai, Dylan R. 分享 收藏
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans Krake, Susann H.; Martinez, Pablo David G.; McLaren, Jenna; Ryan, Eileen; Chen, Gong; White, Karen; Charman, Susan A.; Campbell, Simon; Willis, Paul; Dias, Luiz Carlos 分享 收藏
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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles 开源药物发现: 源自Tres Cantos芳基吡咯的高效抗疟化合物 Williamson, Alice E.; Ylioja, Paul M.; Robertson, Murray N.; Antonova-Koch, Yevgeniya; Avery, Vicky; Baell, Jonathan B.; Batchu, Harikrishna; Batra, Sanjay; Burrows, Jeremy N.; Bhattacharyya, Soumya; Calderon, Felix; Charman, Susan A.; Clark, Julie; Crespo, Benigno; Dean, Matin; Debbert, Stefan L.; Delves, Michael; Dennis, Adelaide S. M.; Deroose, Frederik; Duffy, Sandra; Fletcher, Sabine; Giaever, Guri; Hallyburton, Irene; Gamo, Francisco-Javier; Gebbia, Marinella; Guy, R. Kiplin; Hungerford, Zoe; Kirk, Kiaran; Lafuente-Monasterio, Maria J.; Lee, Anna; Meister, Stephan; Nislow, Corey; Overington, John P.; Papadatos, George; Patiny, Luc; Pham, James; Ralph, Stuart A.; Ruecker, Andrea; Ryan, Eileen; Southan, Christopher; Srivastava, Kumkum; Swain, Chris; Tarnowski, Matthew J.; Thomson, Patrick; Turner, Peter; Wallace, Iain M.; Wells, Timothy N. C.; White, Karen; White, Laura; Willis, Paul; Winzeler, Elizabeth A.; Wittlin, Sergio; Todd, Matthew H. 分享 收藏
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy Baragana, Beatriz; Norcross, Neil R.; Wilson, Caroline; Porzelle, Achim; Hallyburton, Irene; Grimaldi, Raffaella; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; Simeons, Frederick R. C.; Wyatt, Paul G.; Delves, Michael J.; Meister, Stephan; Duffy, Sandra; Avery, Vicky M.; Winzeler, Elizabeth A.; Sinden, Robert E.; Wittlin, Sergio; Frearson, Julie A.; Gray, David W.; Fairlamb, Alan H.; Waterson, David; Campbell, Simon F.; Willis, Paul; Read, Kevin D.; Gilbert, Ian H. 分享 收藏
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Van Voorhis, Wesley C.; Adams, John H.; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H.; Alano, Pietro; Alday, Aintzane; Resto, Yesmalie Aleman; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T.; Avery, Simon V.; Avery, Vicky M.; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Juergen; Boucher, Lauren E.; Boyom, Fabrice F.; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R.; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Cassera, Maria Belen; Cheng, Ken Chih-Chien; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L.; Colon-Lopez, Daisy D.; Corbett, Yolanda; Crowther, Gregory J.; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L.; Du, Alan Y.; Duffy, Sandra; El-Sayed, Shimaa Abd El-Salam; Ferdig, Michael T.; Robledo, Jose A. Fernandez; Fidock, David A.; Florent, Isabelle; Fokou, Patrick V. T.; Galstian, Ani; Javier Gamo, Francisco; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M.; Guha, Rajarshi; Guiguemde, W. Armand; Gural, Nil; Guy, R. Kiplin; Hansen, Michael A. E.; Hanson, Kirsten K.; Hemphill, Andrew; van Huijsduijnen, Rob Hooft; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B.; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A.; Jadhav, Ajit; Jensen, Amornrat Naranuntarat; Jensen, Laran T.; Jiang, Rays H. Y.; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P.; Kyle, Dennis E.; Jose Lafuente, Maria; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M.; Li, Fengwu; Little, David; Liu, Liqiong; Llinas, Manuel; Loza, Maria I.; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R.; March, Sandra; McGowan, Sheena; Vera, Iset Medina; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N.; Misra, Raj N.; Moon, Seunghyun; Moore, John P.; Rodrigues da Costa, Francielly Morais; Mueller, Joachim; Muriana, Arantza; Hewitt, Stephen Nakazawa; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K.; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Ngoc Pham; Prats, Sarah; Plouffe, David M.; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J.; Rice, Christopher A.; Rizk, Mohamed Abdo; Ruecker, Andrea; St Onge, Robert; Ferreira, Rafaela Salgado; Samra, Jasmeet; Robinett, Natalie G.; Schlecht, Ulrich; Schmitt, Marjorie; Villela, Filipe Silva; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A.; Soldati, Thierry; Spitzmueller, Andreas; Stamm, Serge Maximilian; Sullivan, David J.; Sullivan, William; Suresh, Sundari; Suzuki, Brian M.; Suzuki, Yo; Swamidass, S. Joshua; Taramelli, Donatella; Tchokouaha, Lauve R. Y.; Theron, Anjo; Thomas, David; Tonissen, Kathryn F.; Townson, Simon; Tripathi, Abhai K.; Trofimov, Valentin; Udenze, Kenneth O.; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M.; Phat Voong Vinh; Hoan Vu; Watanabe, Nao-aki; Weatherby, Kate; White, Pamela M.; Wilks, Andrew F.; Winzeler, Elizabeth A.; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul H. A.; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoit; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A. 分享 收藏
ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity Maignan, Jordany R.; Lichorowic, Cynthia L.; Giarrusso, James; Blake, Lynn D.; Casandra, Debora; Mutka, Tina S.; LaCrue, Alexis N.; Burrows, Jeremy N.; Willis, Paul A.; Kyle, Dennis E.; Manetsch, Roman 分享 收藏
Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials Norcross, Neil R.; Baragana, Beatriz; Wilson, Caroline; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; Simeons, Frederick R. C.; Porzelle, Achim; Grimaldi, Raffaella; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M.; Meister, Stephan; Sanz, Laura; Jimenez-Diaz, Belen; Angulo-Barturen, Inigo; Ferrer, Santiago; Santos Martinez, Maria; Javier Gamo, Francisco; Frearson, Julie A.; Gray, David W.; Fairlamb, Alan H.; Winzeler, Elizabeth A.; Waterson, David; Campbell, Simon F.; Willis, Paul; Read, Kevin D.; Gilbert, Ian H. 分享 收藏
A broad analysis of resistance development in the malaria parasite Corey, Victoria C.; Lukens, Amanda K.; Istvan, Eva S.; Lee, Marcus C. S.; Franco, Virginia; Magistrado, Pamela; Coburn-Flynn, Olivia; Sakata-Kato, Tomoyo; Fuchs, Olivia; Gnadig, Nina F.; Goldgof, Greg; Linares, Maria; Gomez-Lorenzo, Maria G.; De Cozar, Cristina; Jose Lafuente-Monasterio, Maria; Prats, Sara; Meister, Stephan; Tanaseichuk, Olga; Wree, Melanie; Zhou, Yingyao; Willis, Paul A.; Gamo, Francisco-Javier; Goldberg, Daniel E.; Fidock, David A.; Wirth, Dyann F.; Winzeler, Elizabeth A. 分享 收藏
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