未登录 Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers Koishikawa, Tomoki; Fujiwara, Kaku; Taskar, Kunal; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Chu, Xiaoyan; Hirabayashi, Hideki; Mao, Jialin; Rockich, Kevin; Takashima, Tadayuki; Yamaura, Yoshiyuki; Lai, Yurong; Tomoda, Yukana; Kito, Tomoko; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki 分享 收藏
Membrane transporters in drug development and as determinants of precision medicine 药物开发中的膜转运蛋白和精准医学的决定因素 Galetin, Aleksandra; Brouwer, Kim L. R.; Tweedie, Donald; Yoshida, Kenta; Sjostedt, Noora; Aleksunes, Lauren; Chu, Xiaoyan; Evers, Raymond; Hafey, Michael J.; Lai, Yurong; Matsson, Par; Riselli, Andrew; Shen, Hong; Sparreboom, Alex; Varma, Manthena V. S.; Yang, Jia; Yang, Xinning; Yee, Sook Wah; Zamek-Gliszczynski, Maciej J.; Zhang, Lei; Giacomini, Kathleen M. 分享 收藏
Clinical assessment of gepotidacin (GSK2140944) as a victim and perpetrator of drug-drug interactions via CYP3A metabolism and transporters Barth, Aline; Perry, Caroline R.; Shabbir, Shaila; Zamek-Gliszczynski, Maciej J.; Thomas, Sebin; Dumont, Etienne F.; Brimhall, Darin B.; Nguyen, Dung; Srinivasan, Meenakshi; Swift, Brandon 分享 收藏
Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance Zamek-Gliszczynski, Maciej J.; Sangha, Vishal; Shen, Hong; Feng, Bo; Wittwer, Matthias B.; Varma, Manthena V. S.; Liang, Xiaomin; Sugiyama, Yuichi; Zhang, Lei; Bendayan, Reina 分享 收藏
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective Taskar, Kunal S.; Yang, Xinning; Neuhoff, Sibylle; Patel, Mitesh; Yoshida, Kenta; Paine, Mary F.; Brouwer, Kim L. R.; Chu, Xiaoyan; Sugiyama, Yuichi; Cook, Jack; Polli, Joseph W.; Hanna, Imad; Lai, Yurong; Zamek-Gliszczynski, Maciej 分享 收藏
Physiologically-based pharmacokinetic model-based translation of OATP1B-mediated drug-drug interactions from coproporphyrin I to probe drugs Mochizuki, Tatsuki; Aoki, Yasunori; Yoshikado, Takashi; Yoshida, Kenta; Lai, Yurong; Hirabayashi, Hideki; Yamaura, Yoshiyuki; Rockich, Kevin; Taskar, Kunal; Takashima, Tadayuki; Chu, Xiaoyan; Zamek-Gliszczynski, Maciej J.; Mao, Jialin; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki 分享 收藏
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions Mochizuki, Tatsuki; Zamek-Gliszczynski, Maciej J.; Yoshida, Kenta; Mao, Jialin; Taskar, Kunal; Hirabayashi, Hideki; Chu, Xiaoyan; Lai, Yurong; Takashima, Tadayuki; Rockich, Kevin; Yamaura, Yoshiyuki; Fujiwara, Kaku; Mizuno, Tadahaya; Maeda, Kazuya; Furihata, Kenichi; Sugiyama, Yuichi; Kusuhara, Hiroyuki 分享 收藏
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Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs Unger, Melissa S.; Schumacher, Lena; Enzlein, Thomas; Weigt, David; Zamek-Gliszczynski, Maciej J.; Schwab, Matthias; Nies, Anne T.; Drewes, Gerard; Schulz, Sandra; Reinhard, Friedrich B. M.; Hopf, Carsten 分享 收藏
Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications Zamek-Gliszczynski, Maciej J.; Patel, Mitesh; Yang, Xinning; Lutz, Justin D.; Chu, Xiaoyan; Brouwer, Kim L. R.; Lai, Yurong; Lee, Caroline A.; Neuhoff, Sibylle; Paine, Mary F.; Sugiyama, Yuichi; Taskar, Kunal S.; Galetin, Aleksandra 分享 收藏
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Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium Chu, Xiaoyan; Liao, Mingxiang; Shen, Hong; Yoshida, Kenta; Zur, Arik A.; Arya, Vikram; Galetin, Aleksandra; Giacomini, Kathleen M.; Hanna, Imad; Kusuhara, Hiroyuki; Lai, Yurong; Rodrigues, David; Sugiyama, Yuichi; Zamek-Gliszczynski, Maciej J.; Zhang, Lei 分享 收藏
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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance Zamek-Gliszczynski, Maciej J.; Taub, Mitchell E.; Chothe, Paresh P.; Chu, Xiaoyan; Giacomini, Kathleen M.; Kim, Richard B.; Ray, Adrian S.; Stocker, Sophie L.; Unadkat, Jashvant D.; Wittwer, Matthias B.; Xia, Cindy; Yee, Sook-Wah; Zhang, Lei; Zhang, Yan 分享 收藏
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ITC Commentary on Metformin Clinical Drug-Drug Interaction Study Design That Enables an Efficacy-and Safety-Based Dose Adjustment Decision Zamek-Gliszczynski, Maciej J.; Chu, Xiaoyan; Cook, Jack A.; Custodio, Joseph M.; Galetin, Aleksandra; Giacomini, Kathleen M.; Lee, Caroline A.; Paine, Mary F.; Ray, Adrian S.; Ware, Joseph A.; Wittwer, Matthias B.; Zhang, Lei 分享 收藏
Industry Perspective on Contemporary Protein-Binding Methodologies: Considerations for Regulatory Drug-Drug Interaction and Related Guidelines on Highly Bound Drugs 对当代蛋白质结合方法的行业观点: 监管药物-药物相互作用的考虑以及高结合药物的相关指南 Di, Li; Breen, Christopher; Chambers, Rob; Eckley, Sean T.; Fricke, Robert; Ghosh, Avijit; Harradine, Paul; Kalvass, J. Cory; Ho, Stacy; Lee, Caroline A.; Marathe, Punit; Perkins, Everett J.; Qian, Mark; Tse, Susanna; Yan, Zhengyin; Zamek-Gliszczynski, Maciej J. 分享 收藏
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Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin Nunez, D. J.; Yao, X.; Lin, J.; Walker, A.; Zuo, P.; Webster, L.; Krug-Gourley, S.; Zamek-Gliszczynski, M. J.; Gillmor, D. S.; Johnson, S. L. 分享 收藏
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